?-Tertiary Amines en Route to Natural Products

Dr. Abdul Hameed Dr. Abdul Hameed completed his PhD in Organic Chemistry from The University of Nottingham, UK. He worked in the area of natural products synthesis. He was a post-doc fellow in Max-Planck Institut für Polymerforschung, Germany in synthetic division headed by Prof. Dr. Klaus Müllen. There he worked on the functionalization of adenylyl cyclsase inhibitors via chemical methods to conjugate them with monoclonal antibody to study their biological potential in Regulatory T cells (Treg). His current research interests are including the development of novel methodologies, their utilization in natural products synthesis, the synthesis heterocyclic compound compounds to evaluate their biological potential. Dr. Mariya al-Rashida is a synthetic chemist and has expertise in the area of organic synthesis. She completed Ph.D. in chemistry from the Institute of Chemistry, University of the Punjab, Lahore, Pakistan in 2011. Her area of expertise is synthetic and computational medicinal chemistry. She is currently working towards the synthesis of metalloenzyme inhibitors (carbonic anhydrase, and ecto-nucleotidases). She is an Associate Professor and Chairperson of the Department of Chemistry, Forman Christian College (A Chartered University), Lahore, Pakistan. She has published more than 60 research articles with a cumulative Impact Factor > 150 in various peer review international journals. She has been the recipient of many awards including the prestigious CSP Gold Medal Award for Chemist Under 40. Muhammad Raza Shah is a full professor at the International Center for Chemical and Biological Sciences, HEJ Research Institute of Chemistry, University of Karachi, Pakistan. He is also the Head of the Center for Bioequivalence Studies and Clinical Research. He is a recipient of several awards, including the Tamgha-i-Imtiaz Award from the President of Pakistan, the Salam Prize, the Professor Atta ur Rahman Gold Medal, and the Dr M Raziuddin Siddiqi Prize, by the Pakistan Academy of Sciences, for scientists under 40 years of age, in the field of chemistry. Professor Shah has authored six books and edited four books, in addition to contributing over 350 peer-reviewed journal papers. One of his authored books was declared as best book of 2017 by the Government of Pakistan’s Higher Education Commission.

• 1. Introduction: α,α-Disubsituted α-Amino Acids2. Altemicidin3. Amathaspiramide(A-F)4. Kaitocephalin5. Lactacystin6. Salinosporamide7. Manzacidins (A, C)8. Sphingofungins (E, F) Synthesis9. ACPD ((1S,3R)-1-Aminocyclopentane-1,3-diarboxylic Acid)10. Miscellaneous alkaloids: (+)-LY35470, Piperidine based alkaloids and Tetrodotoxin11. Introduction: α,α-Disubsituted α-Amino Acids12. Altemicidin13. Amathaspiramide(A-F)14. Kaitocephalin15. Lactacystin16. Salinosporamide17. Manzacidins (A, C)18. Sphingofungins (E, F) Synthesis19. ACPD ((1S,3R)-1-Aminocyclopentane-1,3-diarboxylic Acid)20. Miscellaneous alkaloids: (+)-LY35470, Piperidine based alkaloids and Tetrodotoxin