Nima Rezaei, MD, PhD, is Professor of Clinical Immunology and Allergy at Tehran University of Medical Sciences, where he also serves as Associate Dean of International Affairs for the School of Medicine and Director of the Global Academic Program. He is Deputy President of the Research Center for Immunodeficiencies and holds an affiliated research appointment in the Division of Clinical Immunology, Department of Laboratory Medicine, Karolinska Institutet, Sweden. He earned his MD from Tehran University of Medical Sciences and his PhD in Clinical Immunology and Human Genetics from the University of Sheffield, United Kingdom. His research addresses primary immunodeficiencies and translational immunology, with recent work extending into computational and AI-based approaches to immune profiling. He is the founder and President of the Universal Scientific Education and Research Network (USERN) and serves as co-editor of the Springer Nature series Advances in Experimental Medicine and Biology.

• 1. Introduction on therapeutic opportunities for autoimmunity2. Innate lymphoid cells as therapeutic targets in autoimmune diseases3. B regulatory cells in patients with autoimmune diseases: pathogenic significance, therapeutic potential4. Regulatory T cells in autoimmunity and potential therapeutic targets5. Application of IL-6 antagonists in autoimmune disorders6. The search for monomer interaction-based alternative TNFα therapies7. Generation of thymic cells from pluripotent stem cells for basic research and cell therapy8. The NLRP3 inflammasome pathway in autoimmune diseases: a chronotherapeutic perspective?9. Plasmocytes infiltrating autoimmune organs and their putative targeting10. Biological aging and autoimmunity11. Efficacy and safety of biologic treatment in autoimmune diseases12. Nutritional implications for the pathophysiology and treatment of autoimmune disorders13. Dysbiosis and probiotic applications in autoimmune diseases14. Precision medicine in managing chronic conditions with an immunological component15. New advanced therapy medicinal products in treatment of autoimmune diseases16. Targeting of autoimmune disorders through metal nanoformulation in overcoming the fences of conventional treatment approaches17. Immunomodulatory effects of parasites on autoimmunity18. Prediction of autoimmune diseases: from bench to bedside