Dr Khan obtained his medical degree in 1965 followed by postgraduate training in the UK and US. In 1973 he served on the faculty of Case Western Reserve University Cleveland, Ohio, and retired as a tenured full Professor of Medicine in 2012 to become Professor Emeritus of Medicine. He is Fellow of the Royal College of Physicians (FRCP), Master of American College of Physicians (MACP) and American College of Rheumatology (MACR), and a founding member of ASAS, SPARTAN, and GRAPPA devoted to research in AS and SpA. His awards include Distinguished Rheumatologist Award from ACR, Lifetime Achievement Awards from SPARTAN and Ohio Association of Rheumatologists, Spondylitis Association of America's award for "Lifetime of dedication and devotion to people with spondylitis", and their Greg Field Award given to "individuals with AS who have persevered and gone on to be of service to others". He has authored or co-authored seven books on AS-axSpA, over 50 book chapters, and over 250 journal articles.

Written for patients by a patient who is also a leading authority on spondyloarthritis, this book is an essential reference and reading for people living with axial spondyloarthritis — with ankylosing spondylitis as its prototype — and their caregivers who want to learn about the disease and how to manage it well.

• 1: What is ankylosing spondylitis? 2: What is axial spondyloarthritis? 3: What is the underlying cause? HLA-B27 and other disease predisposing genes 4: Disease prevalence 5: Early symptoms 6: Eye inflammation (acute anterior uveitis) 7: Other manifestations 8: Findings on clinical examination and laboratory tests 9: Radiology, MRI, and CT 10: Diagnosis of other forms of SpA and 'look-alikes' 11: Other causes of chronic back pain 12: Assessment of disease activity and functional impairment 13: Patient education 14: Exercise and physical therapy 15: Management: An Overview 16: Management: Patient's role 17: Management: Rheumatologist's role 18: NSAIDs and conventional DMARDs 19: Tumor Necrosis Factor Inhibitors 20: IL-17 and IL-23 inhibitors; and targeted synthetic DMARDs 21: Living with the disease and its socioeconomic impact 22: Fused (ankylosed) spine and risk of fractures 23: Surgical treatment 24: Nontraditional (complementary or alternative) therapy 25: Disease course and effect on lifespan 26: Illustrative case histories Appendix 1: Patient support groups and organizations Appendix 2: Glossary Appendix 3: List of abbreviations Appendix 4: References and further reading

Dr Khan obtained his medical degree in 1965 followed by postgraduate training in the UK and US. In 1973 he served on the faculty of Case Western Reserve University Cleveland, Ohio, and retired as a tenured full Professor of Medicine in 2012 to become Professor Emeritus of Medicine. He is Fellow of the Royal College of Physicians (FRCP), Master of American College of Physicians (MACP) and American College of Rheumatology (MACR), and a founding member of ASAS, SPARTAN, and GRAPPA devoted to research in AS and SpA. His awards include Distinguished Rheumatologist Award from ACR, Lifetime Achievement Awards from SPARTAN and Ohio Association of Rheumatologists, Spondylitis Association of America's award for "Lifetime of dedication and devotion to people with spondylitis", and their Greg Field Award given to "individuals with AS who have persevered and gone on to be of service to others". He has authored or co-authored seven books on AS-axSpA, over 50 book chapters, and over 250 journal articles.

Written for patients by a patient who is also a leading authority on spondyloarthritis, this book is an essential reference and reading for people living with axial spondyloarthritis — with ankylosing spondylitis as its prototype — and their caregivers who want to learn about the disease and how to manage it well.

• 1: What is ankylosing spondylitis? 2: What is axial spondyloarthritis? 3: What is the underlying cause? HLA-B27 and other disease predisposing genes 4: Disease prevalence 5: Early symptoms 6: Eye inflammation (acute anterior uveitis) 7: Other manifestations 8: Findings on clinical examination and laboratory tests 9: Radiology, MRI, and CT 10: Diagnosis of other forms of SpA and 'look-alikes' 11: Other causes of chronic back pain 12: Assessment of disease activity and functional impairment 13: Patient education 14: Exercise and physical therapy 15: Management: An Overview 16: Management: Patient's role 17: Management: Rheumatologist's role 18: NSAIDs and conventional DMARDs 19: Tumor Necrosis Factor Inhibitors 20: IL-17 and IL-23 inhibitors; and targeted synthetic DMARDs 21: Living with the disease and its socioeconomic impact 22: Fused (ankylosed) spine and risk of fractures 23: Surgical treatment 24: Nontraditional (complementary or alternative) therapy 25: Disease course and effect on lifespan 26: Illustrative case histories Appendix 1: Patient support groups and organizations Appendix 2: Glossary Appendix 3: List of abbreviations Appendix 4: References and further reading

Dr Khan obtained his medical degree in 1965 followed by postgraduate training in the UK and US. In 1973 he served on the faculty of Case Western Reserve University Cleveland, Ohio, and retired as a tenured full Professor of Medicine in 2012 to become Professor Emeritus of Medicine. He is Fellow of the Royal College of Physicians (FRCP), Master of American College of Physicians (MACP) and American College of Rheumatology (MACR), and a founding member of ASAS, SPARTAN, and GRAPPA devoted to research in AS and SpA. His awards include Distinguished Rheumatologist Award from ACR, Lifetime Achievement Awards from SPARTAN and Ohio Association of Rheumatologists, Spondylitis Association of America's award for "Lifetime of dedication and devotion to people with spondylitis", and their Greg Field Award given to "individuals with AS who have persevered and gone on to be of service to others". He has authored or co-authored seven books on AS-axSpA, over 50 book chapters, and over 250 journal articles.

Written for patients by a patient who is also a leading authority on spondyloarthritis, this book is an essential reference and reading for people living with axial spondyloarthritis — with ankylosing spondylitis as its prototype — and their caregivers who want to learn about the disease and how to manage it well.

• 1: What is ankylosing spondylitis? 2: What is axial spondyloarthritis? 3: What is the underlying cause? HLA-B27 and other disease predisposing genes 4: Disease prevalence 5: Early symptoms 6: Eye inflammation (acute anterior uveitis) 7: Other manifestations 8: Findings on clinical examination and laboratory tests 9: Radiology, MRI, and CT 10: Diagnosis of other forms of SpA and 'look-alikes' 11: Other causes of chronic back pain 12: Assessment of disease activity and functional impairment 13: Patient education 14: Exercise and physical therapy 15: Management: An Overview 16: Management: Patient's role 17: Management: Rheumatologist's role 18: NSAIDs and conventional DMARDs 19: Tumor Necrosis Factor Inhibitors 20: IL-17 and IL-23 inhibitors; and targeted synthetic DMARDs 21: Living with the disease and its socioeconomic impact 22: Fused (ankylosed) spine and risk of fractures 23: Surgical treatment 24: Nontraditional (complementary or alternative) therapy 25: Disease course and effect on lifespan 26: Illustrative case histories Appendix 1: Patient support groups and organizations Appendix 2: Glossary Appendix 3: List of abbreviations Appendix 4: References and further reading