"Overall, this is a wonderful resource for practicing physicians in internal medicine and cardiology. It is a great reference for diagnosing, treating, and managing heart failure patients in both inpatient and clinic settings." --Rohini Manaktala, D.O. (Ochsner Clinic Foundation) for Doody's Review Service

• Section 1 Basic Mechanisms of Heart Failure1. Molecular Basis for Heart Failure2. Cellular Basis for Heart Failure3. Cellular Basis for Myocardial Regeneration and Repair4. Myocardial Basis for Heart Failure: Role of Cardiac InterstitiumSection 2 Mechanisms of Disease Progression in Heart Failure5. Molecular Signaling Mechanisms of the Renin-Angiotensin System in Heart Failure6. Adrenergic Receptor Signaling in Heart Failure7. Role of Innate Immunity in Heart Failure8. Oxidative Stress in Heart Failure9. Natriuretic Peptides in HF10. Systolic Dysfunction in Heart Failure11. Alterations in Ventricular Function: Diastolic Heart Failure12. Alterations in Ventricular Structure: Role of Left Ventricular Remodeling and Reverse Remodeling in Heart Failure13. Alterations in the Sympathetic and Parasympathetic Nervous Systems in Heart Failure14. Alterations in the Peripheral Circulation in Heart Failure15. Alterations in Kidney Function Associated with Heart Failure16. Alterations in Skeletal Muscle in Heart Failure17. Alterations in Cardiac MetabolismSection 3 Etiological Basis for Heart Failure18. Epidemiology of Heart Failure19. Heart Failure as a Consequence of Ischemic Heart Disease20. Heart Failure as a Consequence of Dilated Cardiomyopathy21. The Restrictive and Infiltrative Cardiomyopathies and Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy22. Cardiac Amyloidosis23. Heart Failure as a Consequence of Hypertrophic Cardiomyopathy24. Heart Failure as a Consequence of Genetic Cardiomyopathy25. Heart Failure as a Consequence of Hypertension26. Heart Failure as a Consequence of Valvular Heart Disease27. Heart Failure as a Consequence of Congenital Heart Disease28. Heart Failure as a Consequence of Viral and Nonviral Myocarditis29. Heart Failure in the Developing World30. Heart Failure and Human Immunodeficiency VirusSection 4 Clinical Assessment of Heart Failure31. Clinical Evaluation of Heart Failure32. Cardiac Imaging in Heart Failure33. Biomarkers and Precision Medicine in Heart Failure34. Hemodynamics in Heart FailureSection 5 Therapy for Heart Failure35. Disease Prevention in Heart Failure36. Management of Acute Decompensated Heart FailureGuidelines37. Contemporary Medical Therapy for Heart Failure Patients with Reduced Ejection FractionGuidelines: Management of Heart Failure with a Reduced Ejection Fraction38. Management of Arrhythmias and Device Therapy in Heart FailureGuidelines39. Treatment of Heart Failure with Preserved Ejection FractionGuidelines40. Management of Heart Failure in Special Populations: Older Patients, Women, and Racial/Ethnic Minority Groups41. Gene and Stem-Cell Based Therapies in Heart Failure42. Neuromodulation in Heart Failure43. Pulmonary Hypertension44. Cardiac Transplantation45. Circulatory Assist Devices in Heart Failure46. Cardio-Oncology and Heart Failure47. Disease Management and Telemedicine in Heart Failure48. Management of Comorbidities in Heart Failure49. Quality and Outcomes in Heart Failure50. Decision Making and Palliative Care in Advanced Heart Failure