"Wow - what a makeover of this renowned textbook of clinical chemistry and molecular diagnostics…. This edition continues its excellence in clinical chemistry and its foray in the past few editions into molecular diagnostics. These chapters are incredibly dense and fact filled; many might suffice as standalone expert treatises." -Reviewed by Valerie L. Ng, PhD, MD (Alameda County Medical Center/Highland Hospital) Doody's Score: 94, 4 Stars!"...The 6th edition of the Tietz textbook hits the mark on many different fronts. In addition to the excellent Editors, Associate Editors, Reviewers, and Contributors to the textbook that make the content extremely valuable, the transformation from the 2012 book to the 2017 platform is what is really exciting. It is clearly evident that the Editors and the Contributors have made an effort to provide the content that is useful for education in the global context..." -Reviewed by: Peter Kavsak, Department of Pathology and Molecular Medicine, McMaster University in Clinical Biochemistry, Volume 50, Issue12

• 1. Laboratory Medicine2. Statistical Methodologies in Laboratory Medicine3. Quality Management in the Clinical Laboratory4. Specimen Collection and Handling5. Preanalytical Variations and Preexamination Processes6. Quality Control7. NEW! Standardization and Harmonization8. Biological Variations9. Reference Intervals10. Evidenced-Based Lab Medicine11. Biobanking12. Lab Support of Pharmaceutical, In Vitro Diagnostics and Epidemiologic Studies13. NEW! Machine Learning and Big Data14. NEW! Utilization of Laboratory Tests15. Lab Safety16. Optical Techniques17. Electrochemistry and Chemical Sensors18. Electrophoresis19. Chromatography20. Mass Spectrometry21. Sample Preparation for Mass Spectrometry Applications22. Mass Spectrometry Applications in Infectious Disease23. Mass Spectrometry for Small Molecule24. Proteomics25. Enzyme and Rate Analysis26. Immunochemical Techniques27. Microfabrication and Microfluidics28. Cytometry29. Automation in the Clinical Lab30. Point-of-Care Testing31. Amino Acids, Peptides, and Proteins32. Serum Enzymes33. Tumor Markers34. Kidney Function Tests35. Carbohydrates36. Lipids and Lipoproteins37. Electrolytes and Blood Gases38. Hormones39. Vitamins and Trace Elements40. Iron Metabolism41. Porphyrins and Porphyrias42. Therapeutic Drug Management43. Clinical Toxicology44. Toxic Elements45. Body Fluids46. Nutrition47. Diabetes Mellitus48. Cardiac Function49. Kidney Disease50. Disorders of Water, Electrolytes, and Acid-Base Metabolism51. Liver Disease52. Gastric, Pancreatic & Intestinal Function53. Monoamine Producing Tumors54. Bone and Mineral Metabolism55. Pituitary Function56. Adrenal Cortex57. Thyroid Disorders58. Reproductive Endocrinology59. Pregnancy and its Disorders60. Newborn Screening and Inborn Errors of Metabolism (Small Molecules)61. Newborn Screening and Inborn Errors of Metabolism (Large Molecules)62. Principles of Molecular Biology63. Nucleic Acid Isolation64. Nucleic Acid Techniques65. Genomes, Variants, and Massively Paralleled Methods66. NEW! Clinical Genome Sequencing67. Molecular Microbiology68. Genetics69. Solid Tumors70. NEW! Hematopathology71. Circulating Tumor Cells and Circulating Nucleic Acids in Oncology72. Circulating Nucleic Acids for Prenatal Diagnostics73. Pharmacogenetics74. Hemostasis75. NEW! Hemoglobin and Hemoglobinopathies76. Automated Hematology77. Red Blood Cell Morphology and Indices with Clinical Chemistry Interface78. NEW! White Blood Cell Morphology79. NEW! Platelets80. NEW! Enzymes of the RBC81. NEW! Overview of Infectious Disease82. NEW! The Role of the Clinical Laboratory in Infection Prevention and Antimicrobial Stewardship83. Bacteriology84. Antimicrobial Susceptibility Testing85. Mycobacteriology86. Mycology87. Parasitology88. Virology89. Blood Groups and Pretransfusion Testing90. Blood Components, Products Modifications, and Blood Donor Screening91. NEW! Indications for Transfusion: RBCs, Platelets, Plasma, and Cryoprecipitate92. NEW! Transfusion Reactions/Adverse Events Associated with Transfusion93. NEW! Allergy Testing94. NEW! Immunogenicity of Biologics95. NEW! Systemic Autoimmune Disease (ANA Testing, RF, CCP, Antibodies, etc.)96. NEW! Primary and Secondary Immunodeficiencies97. NEW! Transplant98. NEW! ImmunogeneticsAppendix. Reference Information for the Clinical Laboratory

"Wow - what a makeover of this renowned textbook of clinical chemistry and molecular diagnostics…. This edition continues its excellence in clinical chemistry and its foray in the past few editions into molecular diagnostics. These chapters are incredibly dense and fact filled; many might suffice as standalone expert treatises." -Reviewed by Valerie L. Ng, PhD, MD (Alameda County Medical Center/Highland Hospital) Doody's Score: 94, 4 Stars!"...The 6th edition of the Tietz textbook hits the mark on many different fronts. In addition to the excellent Editors, Associate Editors, Reviewers, and Contributors to the textbook that make the content extremely valuable, the transformation from the 2012 book to the 2017 platform is what is really exciting. It is clearly evident that the Editors and the Contributors have made an effort to provide the content that is useful for education in the global context..." -Reviewed by: Peter Kavsak, Department of Pathology and Molecular Medicine, McMaster University in Clinical Biochemistry, Volume 50, Issue12

• 1. Laboratory Medicine2. Statistical Methodologies in Laboratory Medicine3. Quality Management in the Clinical Laboratory4. Specimen Collection and Handling5. Preanalytical Variations and Preexamination Processes6. Quality Control7. NEW! Standardization and Harmonization8. Biological Variations9. Reference Intervals10. Evidenced-Based Lab Medicine11. Biobanking12. Lab Support of Pharmaceutical, In Vitro Diagnostics and Epidemiologic Studies13. NEW! Machine Learning and Big Data14. NEW! Utilization of Laboratory Tests15. Lab Safety16. Optical Techniques17. Electrochemistry and Chemical Sensors18. Electrophoresis19. Chromatography20. Mass Spectrometry21. Sample Preparation for Mass Spectrometry Applications22. Mass Spectrometry Applications in Infectious Disease23. Mass Spectrometry for Small Molecule24. Proteomics25. Enzyme and Rate Analysis26. Immunochemical Techniques27. Microfabrication and Microfluidics28. Cytometry29. Automation in the Clinical Lab30. Point-of-Care Testing31. Amino Acids, Peptides, and Proteins32. Serum Enzymes33. Tumor Markers34. Kidney Function Tests35. Carbohydrates36. Lipids and Lipoproteins37. Electrolytes and Blood Gases38. Hormones39. Vitamins and Trace Elements40. Iron Metabolism41. Porphyrins and Porphyrias42. Therapeutic Drug Management43. Clinical Toxicology44. Toxic Elements45. Body Fluids46. Nutrition47. Diabetes Mellitus48. Cardiac Function49. Kidney Disease50. Disorders of Water, Electrolytes, and Acid-Base Metabolism51. Liver Disease52. Gastric, Pancreatic & Intestinal Function53. Monoamine Producing Tumors54. Bone and Mineral Metabolism55. Pituitary Function56. Adrenal Cortex57. Thyroid Disorders58. Reproductive Endocrinology59. Pregnancy and its Disorders60. Newborn Screening and Inborn Errors of Metabolism (Small Molecules)61. Newborn Screening and Inborn Errors of Metabolism (Large Molecules)62. Principles of Molecular Biology63. Nucleic Acid Isolation64. Nucleic Acid Techniques65. Genomes, Variants, and Massively Paralleled Methods66. NEW! Clinical Genome Sequencing67. Molecular Microbiology68. Genetics69. Solid Tumors70. NEW! Hematopathology71. Circulating Tumor Cells and Circulating Nucleic Acids in Oncology72. Circulating Nucleic Acids for Prenatal Diagnostics73. Pharmacogenetics74. Hemostasis75. NEW! Hemoglobin and Hemoglobinopathies76. Automated Hematology77. Red Blood Cell Morphology and Indices with Clinical Chemistry Interface78. NEW! White Blood Cell Morphology79. NEW! Platelets80. NEW! Enzymes of the RBC81. NEW! Overview of Infectious Disease82. NEW! The Role of the Clinical Laboratory in Infection Prevention and Antimicrobial Stewardship83. Bacteriology84. Antimicrobial Susceptibility Testing85. Mycobacteriology86. Mycology87. Parasitology88. Virology89. Blood Groups and Pretransfusion Testing90. Blood Components, Products Modifications, and Blood Donor Screening91. NEW! Indications for Transfusion: RBCs, Platelets, Plasma, and Cryoprecipitate92. NEW! Transfusion Reactions/Adverse Events Associated with Transfusion93. NEW! Allergy Testing94. NEW! Immunogenicity of Biologics95. NEW! Systemic Autoimmune Disease (ANA Testing, RF, CCP, Antibodies, etc.)96. NEW! Primary and Secondary Immunodeficiencies97. NEW! Transplant98. NEW! ImmunogeneticsAppendix. Reference Information for the Clinical Laboratory