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• SECTION I Care of the Acutely Ill Child1 Assessment of the Acutely Ill Child2 Resuscitation, 93 Shock and Sepsis,4 Acute Abdominopelvic Emergencies,5 Drowning in Children6 Burns7 Injury and Trauma,8 Poisoning and Ingestion9 Brief Resolved Unexplained Event and Sudden Infant Death Syndrome10 Child Abuse and NeglectSECTION II Care of the Complex Child11 Symptom Evaluation and Management in Children With Medical Complexity12 Respiratory Considerations in Children With Medical Complexity13 Feeding and Nutrition in Children With Medical Complexity14 Devices and Technology for Children With Medical ComplexitySECTION III Adolescent Medicine15 Behavioral Health Conditions16 Dysmenorrhea and Abnormal Uterine Bleeding17 Polycystic Ovarian Syndrome in Adolescents18 Transgender and Gender Diverse Youth19 Adolescent Sexual HealthSECTION IV Allergy and Immunology20 Anaphylaxis21 Urticaria and Angioedema22 Allergic Rhinitistta23 Immune DeficiencySECTION V Bone and Joint Disorders24 Disorders of the Neck and Spine25 Disorders of the Hip and Lower Extremity26 Common Fractures27 Pediatric Sports Medicine28 Osteomyelitis and Other Bone and Joint InfectionsSECTION VI Cardiology29 Development of the Cardiovascular System30 Acyanotic Congenital Heart Disease31 Cyanotic Congenital Heart Disease32 Arrhythmias33 Heart Failure and Cardiomyopathy34 Cardiac Evaluation of Chest Pain, Syncope, and Palpitations35 Acquired Heart DiseaseSECTION VII Dermatology36 Dermatologic Morphology37 Acne38 Nevi39 Atopic Dermatitis40 Vascular Disorders41 Hyperpigmented Skin Disorders42 Hypopigmented Skin Lesions43 Nutritional Dermatoses44 Drug Eruptions45 Dermatologic Bacterial InfectionsSECTION VIII Endocrinology46 Puberty47 Thyroid Disease48 Disorders of Calcium and Bone Metabolism49 Disorders of the Adrenal Gland50 Diabetes Mellitus51 Hypoglycemia52 Disorders of Growth53 Endocrine DysnatremiasSECTION IX Gastroenterology54 Diarrhea55 Constipation56 Gastritis and Gastrointestinal Bleeding57 Inflammatory Bowel Disease58 Hernias59 Disorders of the Esophagus60 Intestinal Obstruction and Malrotation61 Disorders of the Pancreas62 Hepatobiliary Disease63 Infections in the Gastrointestinal TractSECTION X Genetics and Metabolism64 Overview of Genetic Testing and Newborn Screening65 Chromosomal Disorders66 Syndromes With Congenital Anomalies67 Syndromic Intellectual Disability68 Musculoskeletal and Connective Tissue Disorders69 Metabolic Disorders ICONTENTS70 Metabolic Disorders II71 Mitochondrial DisordersSECTION XI Head and Neck Disorders72 Disorders of the Eye73 Disorders of the Ear and Audition74 Disorders of the Nose and Sinuses75 Disorders of Dentition and Oral Cavity76 Disorders of the NeckSECTION XII Hematology77 Disorders of Red Blood Cells78 Disorders of White Blood Cells79 Platelet Disorders80 Sickle Cell Disease81 Disorders of Thrombosis and HemostasisSECTION XIII Infectious Diseases82 The Febrile Infant83 Fever of Unknown Origin84 Fever in a Returning Traveler85 Tick-Borne Illness86 Human Immunodeficiency Virus87 Tuberculosis88 Viral Infections89 Fungal Infections90 Parasitic DiseasesSECTION XIV Neonatal Medicine91 Newborn Examination92 Assessment of the Acutely Ill Neonate93 Disorders of the Respiratory System94 Disorders of the Gastrointestinal Tract95 Hematologic Disorders of the Neonate96 Hyperbilirubinemia97 Neonatal Dermatology98 Disorders of the Nervous System99 Neonatal InfectionsSECTION XV Nephrology and Urology100 Hematuria and Proteinuria101 Hypertension102 Glomerulonephritis103 Nephrotic Syndrome104 Hemolytic-Uremic Syndrome105 Acute Kidney Injury and Chronic Kidney Disease106 Congenital Anomalies of the Kidney and Urinary Tract107 Infections of the Urinary TractCONTENTSSECTION XVI Neurology108 Seizures109 Headache110 Stroke111 Neurocutaneous Disorders112 Movement Disorders113 Encephalopathies114 Demyelinating Diseases115 Spinal Cord Disorders116 Neuromuscular Disorders117 Neurologic Emergencies118 Infectious Diseases of the Central Nervous SystemSECTION XVII Nutrition119 Nutritional Requirements and Growth120 Acute and Chronic Malnutritionn121 Obesity122 Nutritional DeficienciesSECTION XVIII Oncology123 Leukemia124 Lymphomas125 Brain Tumors126 Neuroblastoma127 Renal Neoplasms128 Bone Neoplasms129 Rhabdomyosarcoma130 Histiocyte DisordersSECTION XIX Pulmonology131 Asthma132 Cystic Fibrosis and Primary Ciliary Dyskinesia133 Sleep Medicine134 Congenital Anomalies of the Lung135 Infections of the Lower AirwaySECTION XX Rheumatology136 Chronic Arthritis137 Juvenile Dermatomyositis138 Vasculitis and Vasculopathy139 Systemic Lupus Erythematosus140 Granulomatous Disease

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• SECTION I Care of the Acutely Ill Child1 Assessment of the Acutely Ill Child2 Resuscitation, 93 Shock and Sepsis,4 Acute Abdominopelvic Emergencies,5 Drowning in Children6 Burns7 Injury and Trauma,8 Poisoning and Ingestion9 Brief Resolved Unexplained Event and Sudden Infant Death Syndrome10 Child Abuse and NeglectSECTION II Care of the Complex Child11 Symptom Evaluation and Management in Children With Medical Complexity12 Respiratory Considerations in Children With Medical Complexity13 Feeding and Nutrition in Children With Medical Complexity14 Devices and Technology for Children With Medical ComplexitySECTION III Adolescent Medicine15 Behavioral Health Conditions16 Dysmenorrhea and Abnormal Uterine Bleeding17 Polycystic Ovarian Syndrome in Adolescents18 Transgender and Gender Diverse Youth19 Adolescent Sexual HealthSECTION IV Allergy and Immunology20 Anaphylaxis21 Urticaria and Angioedema22 Allergic Rhinitistta23 Immune DeficiencySECTION V Bone and Joint Disorders24 Disorders of the Neck and Spine25 Disorders of the Hip and Lower Extremity26 Common Fractures27 Pediatric Sports Medicine28 Osteomyelitis and Other Bone and Joint InfectionsSECTION VI Cardiology29 Development of the Cardiovascular System30 Acyanotic Congenital Heart Disease31 Cyanotic Congenital Heart Disease32 Arrhythmias33 Heart Failure and Cardiomyopathy34 Cardiac Evaluation of Chest Pain, Syncope, and Palpitations35 Acquired Heart DiseaseSECTION VII Dermatology36 Dermatologic Morphology37 Acne38 Nevi39 Atopic Dermatitis40 Vascular Disorders41 Hyperpigmented Skin Disorders42 Hypopigmented Skin Lesions43 Nutritional Dermatoses44 Drug Eruptions45 Dermatologic Bacterial InfectionsSECTION VIII Endocrinology46 Puberty47 Thyroid Disease48 Disorders of Calcium and Bone Metabolism49 Disorders of the Adrenal Gland50 Diabetes Mellitus51 Hypoglycemia52 Disorders of Growth53 Endocrine DysnatremiasSECTION IX Gastroenterology54 Diarrhea55 Constipation56 Gastritis and Gastrointestinal Bleeding57 Inflammatory Bowel Disease58 Hernias59 Disorders of the Esophagus60 Intestinal Obstruction and Malrotation61 Disorders of the Pancreas62 Hepatobiliary Disease63 Infections in the Gastrointestinal TractSECTION X Genetics and Metabolism64 Overview of Genetic Testing and Newborn Screening65 Chromosomal Disorders66 Syndromes With Congenital Anomalies67 Syndromic Intellectual Disability68 Musculoskeletal and Connective Tissue Disorders69 Metabolic Disorders ICONTENTS70 Metabolic Disorders II71 Mitochondrial DisordersSECTION XI Head and Neck Disorders72 Disorders of the Eye73 Disorders of the Ear and Audition74 Disorders of the Nose and Sinuses75 Disorders of Dentition and Oral Cavity76 Disorders of the NeckSECTION XII Hematology77 Disorders of Red Blood Cells78 Disorders of White Blood Cells79 Platelet Disorders80 Sickle Cell Disease81 Disorders of Thrombosis and HemostasisSECTION XIII Infectious Diseases82 The Febrile Infant83 Fever of Unknown Origin84 Fever in a Returning Traveler85 Tick-Borne Illness86 Human Immunodeficiency Virus87 Tuberculosis88 Viral Infections89 Fungal Infections90 Parasitic DiseasesSECTION XIV Neonatal Medicine91 Newborn Examination92 Assessment of the Acutely Ill Neonate93 Disorders of the Respiratory System94 Disorders of the Gastrointestinal Tract95 Hematologic Disorders of the Neonate96 Hyperbilirubinemia97 Neonatal Dermatology98 Disorders of the Nervous System99 Neonatal InfectionsSECTION XV Nephrology and Urology100 Hematuria and Proteinuria101 Hypertension102 Glomerulonephritis103 Nephrotic Syndrome104 Hemolytic-Uremic Syndrome105 Acute Kidney Injury and Chronic Kidney Disease106 Congenital Anomalies of the Kidney and Urinary Tract107 Infections of the Urinary TractCONTENTSSECTION XVI Neurology108 Seizures109 Headache110 Stroke111 Neurocutaneous Disorders112 Movement Disorders113 Encephalopathies114 Demyelinating Diseases115 Spinal Cord Disorders116 Neuromuscular Disorders117 Neurologic Emergencies118 Infectious Diseases of the Central Nervous SystemSECTION XVII Nutrition119 Nutritional Requirements and Growth120 Acute and Chronic Malnutritionn121 Obesity122 Nutritional DeficienciesSECTION XVIII Oncology123 Leukemia124 Lymphomas125 Brain Tumors126 Neuroblastoma127 Renal Neoplasms128 Bone Neoplasms129 Rhabdomyosarcoma130 Histiocyte DisordersSECTION XIX Pulmonology131 Asthma132 Cystic Fibrosis and Primary Ciliary Dyskinesia133 Sleep Medicine134 Congenital Anomalies of the Lung135 Infections of the Lower AirwaySECTION XX Rheumatology136 Chronic Arthritis137 Juvenile Dermatomyositis138 Vasculitis and Vasculopathy139 Systemic Lupus Erythematosus140 Granulomatous Disease

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• SECTION I Care of the Acutely Ill Child1 Assessment of the Acutely Ill Child2 Resuscitation, 93 Shock and Sepsis,4 Acute Abdominopelvic Emergencies,5 Drowning in Children6 Burns7 Injury and Trauma,8 Poisoning and Ingestion9 Brief Resolved Unexplained Event and Sudden Infant Death Syndrome10 Child Abuse and NeglectSECTION II Care of the Complex Child11 Symptom Evaluation and Management in Children With Medical Complexity12 Respiratory Considerations in Children With Medical Complexity13 Feeding and Nutrition in Children With Medical Complexity14 Devices and Technology for Children With Medical ComplexitySECTION III Adolescent Medicine15 Behavioral Health Conditions16 Dysmenorrhea and Abnormal Uterine Bleeding17 Polycystic Ovarian Syndrome in Adolescents18 Transgender and Gender Diverse Youth19 Adolescent Sexual HealthSECTION IV Allergy and Immunology20 Anaphylaxis21 Urticaria and Angioedema22 Allergic Rhinitistta23 Immune DeficiencySECTION V Bone and Joint Disorders24 Disorders of the Neck and Spine25 Disorders of the Hip and Lower Extremity26 Common Fractures27 Pediatric Sports Medicine28 Osteomyelitis and Other Bone and Joint InfectionsSECTION VI Cardiology29 Development of the Cardiovascular System30 Acyanotic Congenital Heart Disease31 Cyanotic Congenital Heart Disease32 Arrhythmias33 Heart Failure and Cardiomyopathy34 Cardiac Evaluation of Chest Pain, Syncope, and Palpitations35 Acquired Heart DiseaseSECTION VII Dermatology36 Dermatologic Morphology37 Acne38 Nevi39 Atopic Dermatitis40 Vascular Disorders41 Hyperpigmented Skin Disorders42 Hypopigmented Skin Lesions43 Nutritional Dermatoses44 Drug Eruptions45 Dermatologic Bacterial InfectionsSECTION VIII Endocrinology46 Puberty47 Thyroid Disease48 Disorders of Calcium and Bone Metabolism49 Disorders of the Adrenal Gland50 Diabetes Mellitus51 Hypoglycemia52 Disorders of Growth53 Endocrine DysnatremiasSECTION IX Gastroenterology54 Diarrhea55 Constipation56 Gastritis and Gastrointestinal Bleeding57 Inflammatory Bowel Disease58 Hernias59 Disorders of the Esophagus60 Intestinal Obstruction and Malrotation61 Disorders of the Pancreas62 Hepatobiliary Disease63 Infections in the Gastrointestinal TractSECTION X Genetics and Metabolism64 Overview of Genetic Testing and Newborn Screening65 Chromosomal Disorders66 Syndromes With Congenital Anomalies67 Syndromic Intellectual Disability68 Musculoskeletal and Connective Tissue Disorders69 Metabolic Disorders ICONTENTS70 Metabolic Disorders II71 Mitochondrial DisordersSECTION XI Head and Neck Disorders72 Disorders of the Eye73 Disorders of the Ear and Audition74 Disorders of the Nose and Sinuses75 Disorders of Dentition and Oral Cavity76 Disorders of the NeckSECTION XII Hematology77 Disorders of Red Blood Cells78 Disorders of White Blood Cells79 Platelet Disorders80 Sickle Cell Disease81 Disorders of Thrombosis and HemostasisSECTION XIII Infectious Diseases82 The Febrile Infant83 Fever of Unknown Origin84 Fever in a Returning Traveler85 Tick-Borne Illness86 Human Immunodeficiency Virus87 Tuberculosis88 Viral Infections89 Fungal Infections90 Parasitic DiseasesSECTION XIV Neonatal Medicine91 Newborn Examination92 Assessment of the Acutely Ill Neonate93 Disorders of the Respiratory System94 Disorders of the Gastrointestinal Tract95 Hematologic Disorders of the Neonate96 Hyperbilirubinemia97 Neonatal Dermatology98 Disorders of the Nervous System99 Neonatal InfectionsSECTION XV Nephrology and Urology100 Hematuria and Proteinuria101 Hypertension102 Glomerulonephritis103 Nephrotic Syndrome104 Hemolytic-Uremic Syndrome105 Acute Kidney Injury and Chronic Kidney Disease106 Congenital Anomalies of the Kidney and Urinary Tract107 Infections of the Urinary TractCONTENTSSECTION XVI Neurology108 Seizures109 Headache110 Stroke111 Neurocutaneous Disorders112 Movement Disorders113 Encephalopathies114 Demyelinating Diseases115 Spinal Cord Disorders116 Neuromuscular Disorders117 Neurologic Emergencies118 Infectious Diseases of the Central Nervous SystemSECTION XVII Nutrition119 Nutritional Requirements and Growth120 Acute and Chronic Malnutritionn121 Obesity122 Nutritional DeficienciesSECTION XVIII Oncology123 Leukemia124 Lymphomas125 Brain Tumors126 Neuroblastoma127 Renal Neoplasms128 Bone Neoplasms129 Rhabdomyosarcoma130 Histiocyte DisordersSECTION XIX Pulmonology131 Asthma132 Cystic Fibrosis and Primary Ciliary Dyskinesia133 Sleep Medicine134 Congenital Anomalies of the Lung135 Infections of the Lower AirwaySECTION XX Rheumatology136 Chronic Arthritis137 Juvenile Dermatomyositis138 Vasculitis and Vasculopathy139 Systemic Lupus Erythematosus140 Granulomatous Disease