Feigin and Cherry's Textbook of Pediatric Infectious Diseases

James D. Cherry, MD, MSc is a Distinguished Research Professor at the David Geffen School of Medicine at UCLA and UCLA Mattel Children's Hospital, Division of Infectious Diseases. Dr. Cherry established one of the first formal pediatric infectious disease fellowship programs in the world in 1963 at the University of Wisconsin. In 1973 Dr. Cherry started the first pediatric infectious training program at UCLA. During his 43 years tenure at UCLA, numerous trainees have gone on to be leaders in pediatric infectious diseases in the US and around the world. Dr. Cherry has won many awards during his career. John V. Williams, MD, a leading expert on respiratory viruses that infect children, is chair of the Department of Pediatrics at the University of Wisconsin School of Medicine and Public Health.

4 Stars! "...delivers detailed reviews of clinical syndromes and microbial pathogens [and] aims to provide a comprehensive and authoritative review of important infectious diseases topics. The aims of this collection are appropriate and well-addressed throughout the text, providing an excellent summary of each topic presented... This book covers a wide breadth of infectious diseases topics, starting with a detailed review of host-pathogen pathogenesis, followed by a syndromic approach... [A] well-organized [book] in an intuitive manner, with easy online access, as well... The content is visually cohesive on a desktop browser. Links are also easy to navigate and connect appropriately. The newest edition of this book remains an important reference for healthcare professionals in general and pediatric infectious diseases specialists, in particular... It addresses important and timely topics, remaining relevant in a fluid and ever-changing field. I recommend this book to anyone who manages infectious diseases in pediatric patients to any degree." Review by Clayton Mowrer, DO, MBA, MPH (University of Nebraska Medical Center), ©Doody's Review Service 2025. Doody's Score: 93, 4 Stars!"The extensively revised, updated and enlarged 9th edition of this classic Textbook is an important tool in the treatment of infectious diseases in the pediatric population and beyond. The present text is divided into 2 volumes: 6 parts [and] each part is divided into subsections. In total there are 271 chapters written by experts from several countries. Each chapter contains tables and illustrations, all in color.... An e-book can be activated [which] contains the text, tables, figures and all the references.... [It's] very highly recommended for every pediatrician and pediatric department." - Pediatric Endocrinology Review, 2025

• 1 Molecular Determinants of Microbial Pathogenesis2 Normal and Impaired Immunologic Responses to Infection3 The Host Response to Infections: The “-omics” Revolution4 Fever: Pathogenesis and Treatment5 The Human Microbiome6 Epidemiology and Biostatistics of Infectious DiseasesSECTION 1 Upper Respiratory Tract Infections7 The Common Cold8 Infections of the Oral Cavity9 Pharyngitis (Pharyngitis, Tonsillitis, Tonsillopharyngitis, and Nasopharyngitis)10 Uvulitis11 Peritonsillar, Retropharyngeal, and Parapharyngeal Abscesses12 Cervical Lymphadenitis13 Parotitis14 Rhinosinusitis15 Otitis Externa16 Otitis Media17 Mastoiditis18 Croup (Laryngitis, Laryngotracheitis, Spasmodic Croup, Laryngotracheobronchitis, Bacterial Tracheitis, and Laryngotracheobronchopneumonitis) and Epiglottitis (Supraglottitis)SECTION 2 Lower Respiratory Tract Infections19 Acute Bronchitis20 Chronic Bronchitis21 Bronchiolitis and Infectious Asthma22 Pediatric Community-Acquired Pneumonia23 Empyema and Lung Abscess24 Children’s Interstitial Lung Disease and Hypersensitivity Pneumonitis25 Cystic FibrosisSECTION 3 Infections of the Heart26 Infective Endocarditis27 Infectious Pericarditis28 Myocarditis29 Acute Rheumatic Fever30 MediastinitisSECTION 4 Central Nervous System Infections31 Bacterial Meningitis Beyond the Neonatal Period32 Parameningeal Infections33 Fungal Meningitis34 Eosinophilic Meningitis35 Aseptic Meningitis and Viral Meningitis36 Encephalitis and Meningoencephalitis37 Parainfectious and Postinfectious Demyelinating Disorders of the Central Nervous System38 Infection-Associated Myelitis and Myelopathies of the Spinal Cord39 Guillain-Barré SyndromeSECTION 5 Genitourinary Tract Infections40 Urethritis41 Cystitis and Pyelonephritis42 Renal Abscess43 Prostatitis44 Female Genital InfectionsSECTION 6 Gastrointestinal Tract Infections45 Esophagitis46 Approach to Patients With Gastrointestinal Tract Infections and Food Poisoning47 Clostridioides difficile Infection48 Whipple DiseaseSECTION 7 Liver Diseases49 Hepatitis50 Cholangitis and Cholecystitis51 Pyogenic Liver Abscess52 Reye SyndromeSECTION 8 Other Intraabdominal Infections53 Appendicitis and Pelvic Abscess54 Pancreatitis55 Peritonitis and Intraabdominal Abscess56 Retroperitoneal InfectionsSECTION 9 Musculoskeletal Infections57 Osteomyelitis58 Septic Arthritis59 Bacterial Myositis and PyomyositisSECTION 10 Skin Infections60 Cutaneous Manifestations of Systemic Infections61 Roseola Infantum (Exanthem Subitum)62 Bacterial Skin InfectionsSECTION 11 Ocular Infectious Diseases64 Ocular InfectionsSECTION 12 Systemic Infectious Diseases65 Bacteremia and Septic Shock66 Fever Without Source and Fever of Unknown Origin67 Toxic Shock SyndromeSECTION 13 Infections of the Fetus and Newborn68 Approach to Infections in the Fetus and NewbornSECTION 14 Infections of the Compromised Host69 Inborn Errors of Immunity (Primary Immunodeficiencies)70 The Febrile Neutropenic Patient71 Opportunistic Infections in Hematopoietic Stem Cell Transplantation72 Infections in Pediatric Heart Transplantation73 Infections in Pediatric Lung Transplantation74 Opportunistic Infections in Liver and Intestinal Transplantation75 Infections in Renal Transplantation76 Infections Related to Prosthetic or Artificial Devices77 Infections in Burn PatientsSECTION 15 Unclassified Infectious Diseases78 Kawasaki Disease79 Chronic Fatigue Syndrome (Systemic Exertion Intolerance Disease)SECTION 16 Bacterial InfectionsSUBSECTION I Gram-Positive Cocci80 Staphylococcus aureus Infections (Coagulase-Positive Staphylococci)81 Coagulase-Negative Staphylococcal Infections82 Group A, Group C, and Group G ?-Hemolytic Streptococcal Infections83 Group B Streptococcal Infections84 Enterococcal and Viridans Streptococcal Infections85 Pneumococcal Infections86 Miscellaneous Gram-Positive CocciSUBSECTION II Gram-Negative Cocci87 Moraxella catarrhalis88 Meningococcal Disease89 Gonococcal InfectionsSUBSECTION III Gram-Positive Bacilli90 Diphtheria91 Anthrax92 Bacillus cereus and Other Bacillus Species93 Arcanobacterium haemolyticum94 Erysipelothrix rhusiopathiae95 Listeriosis96 Tuberculosis97 Other Mycobacteria98 Leprosy and Buruli Ulcer: The Major Cutaneous Mycobacterioses99 Nocardia100 Corynebacterium and RhodococcusSUBSECTION IV Gram-Negative Bacilli101 Citrobacter102 Enterobacter103 Extraintestinal Pathogenic Escherichia coli104 Diarrhea-Causing and Dysentery-Causing Escherichia coli105 Klebsiella106 Morganella morganii107 Proteus108 Providencia109 Shigella110 Serratia111 Salmonella112 Plague (Yersinia pestis)113 Other Yersinia Species114 Miscellaneous Enterobacteriaceae115 Aeromonas116 Pasteurella multocida117 Cholera118 Vibrio parahaemolyticus119 Vibrio vulnificus120 Miscellaneous Non-Enterobacteriaceae Fermentative Bacilli121 Acinetobacter122 Achromobacter (Alcaligenes)123 Eikenella corrodens124 Elizabethkingia and Chryseobacterium Species125 Pseudomonas and Related Genera126 Stenotrophomonas (Xanthomonas) maltophiliaSUBSECTION V Gram-Negative Coccobacilli127 Aggregatibacter Species128 Brucellosis129 Pertussis and Other Bordetella Infections130 Donovanosis (Granuloma inguinale)131 Campylobacter Species132 Tularemia133 Haemophilus influenzae134 Other Haemophilus Species (ducreyi, haemolyticus, influenzae biogroup aegyptius, and parainfluenzae)135 Helicobacter pylori136 Kingella kingae137 Legionnaires’ Disease, Pontiac Fever, and Related Illnesses138 Q Fever139 Streptobacillus moniliformis (Rat-Bite Fever)140 Bartonella InfectionsSUBSECTION VI Treponemataceae141 Lyme Disease142 Relapsing Fever143 Leptospirosis144 Spirillum minus (Rat-Bite Fever)145 Syphilis146 Nonvenereal TreponematosesSUBSECTION VII Anaerobic Bacteria147 Clostridial Intoxication and Infection148 Infant Botulism149 Tetanus150 Actinomycosis151 Bacteroides, Fusobacterium, Prevotella, and PorphyromonasSECTION 17 Viral InfectionsSUBSECTION I DNA-Parvoviridae152 Human Parvovirus B19153 Human BocavirusesSUBSECTION II DNA-Polyomaviridae154 Human Polyomaviruses155 Human PapillomavirusesSUBSECTION III DNA-Adenoviridae156 AdenovirusesSUBSECTION IV DNA-Hepatoviridae157 Hepatitis B and D VirusesSUBSECTION V DNA-Herpesviridae158 Herpes Simplex Viruses 1 and 2159 Cytomegalovirus160 Epstein-Barr Virus161 Human Herpesviruses 6A, 6B, 7, and 8162 Varicella Zoster VirusSUBSECTION VI DNA-Poxviridae163 Smallpox (Variola Virus)164 Monkeypox and Other Poxviruses165 MimivirusesSUBSECTION I RNA-Picornaviridae166 Enteroviruses, Parechoviruses, and Saffold Viruses167 Rhinoviruses168 Hepatitis A VirusSUBSECTION II RNA-Caliciviridae169 Caliciviruses170 Hepatitis E VirusSUBSECTION III RNA-Reoviridae171 Reoviruses172 Orbiviruses, Coltiviruses, and Seadornaviruses: Colorado Tick Fever, Banna Virus, and Others173 RotavirusSUBSECTION IV RNA-Togaviridae174 Rubella Virus175 Eastern Equine Encephalitis176 Western Equine Encephalitis177 Venezuelan Equine Encephalitis178 Chikungunya179 Ross River Virus Arthritis180 Other Alphaviral InfectionsSUBSECTION V Flaviviridae181 St. Louis Encephalitis182 West Nile Virus183 Yellow Fever184 Dengue, Dengue Hemorrhagic Fever, and Severe Dengue185 Japanese Encephalitis186 Murray Valley Encephalitis187 Tick-Borne Encephalitis188 Zika Virus Infections189 Other Less Commonly Recognized Flaviviruses190 Hepatitis C VirusSUBSECTION VI Orthomyxoviridae191 Influenza VirusesSUBSECTION VII Paramyxoviridae192 Parainfluenza Viruses193 Measles Virus194 Mumps Virus195 Respiratory Syncytial Virus196 Human MetapneumovirusSUBSECTION VIII Rhabdoviridae197 Rabies VirusSUBSECTION IX Arenaviridae and Filoviridae198 Lymphocytic Choriomeningitis Virus199 Arenaviral Hemorrhagic Fevers200 Filoviral Hemorrhagic Fever: Marburg and Ebola Virus FeversSUBSECTION X Coronaviridae and Torovirdae201 Human CoronavirusesSUBSECTION XI Bunyaviridae202 Hantaviruses203 La Crosse Virus and Other California Serogroup Viruses204 Rift Valley Fever205 Crimean-Congo Hemorrhagic Fever206 Phlebotomus Fever (Sandfly Fever),207 Oropouche Fever208 Toscana VirusSUBSECTION XII Retroviridae209 Oncoviruses (Human T-Cell Lymphotropic Viruses) and Lentiviruses (Human Immunodeficiency Virus Type 2)210 Human Immunodeficiency Virus and Acquired Immunodeficiency SyndromeSUBSECTION XIII Prion-Related Diseases211 Transmissible Spongiform Encephalopathies (Creutzfeldt-Jakob Disease, Gerstmann-Sträussler-Scheinker Disease, Kuru, Fatal Familial Insomnia, New Variant Creutzfeldt-Jakob Disease, Sporadic Fatal Insomnia, Variably Protease Sensitive Prionopathy)SECTION 18 Chlamydia212 Chlamydia InfectionsSECTION 19 Rickettsial Diseases213 Rickettsial and Ehrlichial DiseasesSECTION 20 Mycoplasma214 Mycoplasma and Ureaplasma InfectionsSECTION 21 Fungal Diseases215 Aspergillosis216 Blastomycosis217 Candidiasis218 Coccidioidomycosis219 Paracoccidioidomycosis220 Cryptococcosis221 Histoplasmosis222 Sporotrichosis223 Mucormycosis and Entomophthoramycosis224 Fusariosis and Scedosporiosis225 Miscellaneous MycosesSECTION 22 Parasitic DiseasesSUBSECTION I Protozoa226 Amebiasis227 Blastocystis hominis and Blastocystis spp. Infection228 Entamoeba coli Infection229 Giardiasis230 Dientamoeba fragilis Infections231 Trichomonas Infections232 Balantidium coli Infection233 Cryptosporidiosis234 Cyclosporiasis, Cystoisosporiasis, and Microsporidiosis235 Babesiosis236 Malaria237 Leishmaniasis238 Trypanosomiasis239 Naegleria, Acanthamoeba, and Balamuthia Infections240 Toxoplasmosis241 Pneumocystis PneumoniaSUBSECTION II Nematodes242 Parasitic Nematode InfectionsSUBSECTION III Cestodes243 CestodesSUBSECTION IV Trematodes244 Foodborne Trematodes245 SchistosomiasisSUBSECTION V Arthropods246 ArthropodsSECTION 23 Global Health247 Global Health248 International Travel Considerations for Children249 Infectious Disease Considerations in International Adoptees and Refugees250 Antibiotic Resistance251 The Pharmacokinetic-Pharmacodynamic Interface: Determinants of Antiinfective Drug Action and Efficacy in Pediatrics252 Antibacterial Therapeutic Agents253 Antimicrobial Prophylaxis254 Outpatient Intravenous Antimicrobial Therapy for Serious Infections255 Antiviral Agents256 Antifungal Agents257 Drugs for Parasitic Infections258 Immunomodulating Agents259 Probiotics260 Health Care-Associated Infections261 Antimicrobial Stewardship262 Active Immunizing Agents263 Passive ImmunizationSECTION 24 Other Preventive Considerations264 Public Health Aspects of Infectious Disease Control265 Infections in Out-of-Home Childcare266 Animal and Human Bites267 Bioterrorism268 Bacterial Laboratory Diagnosis269 Fungal Diagnostics for Pediatric Patients270 Viral Laboratory Diagnosis271 Parasitic Laboratory Diagnosis