Bland and Copeland's The Breast

Kirby I. Bland, M.D., is Professor Emeritus and Chair Emeritus in the University of Alabama at Birmingham (UAB) Department of Surgery. An internationally recognized leader in surgical oncology, Dr. Bland has made significant contributions to breast cancer research, translational science, and surgical education. He has served as principal investigator and program leader for multiple National Cancer Institute Specialized Programs of Research Excellence (SPORE) grants, with research focused on targeted therapies and chemoprevention for breast cancer and melanoma. Dr. Bland has authored or co-authored nearly 600 peer-reviewed publications and authored or edited 44 textbooks, including The Breast: Comprehensive Management of Benign and Malignant Diseases, a leading reference in the field. He has also served as president of numerous national surgical societies, reflecting his longstanding leadership and impact on academic surgery and surgical oncology. V. Suzanne Klimberg, M.D., is the Courtney M. Townsend, Jr., M.D. Distinguished Chair in General Surgery, Professor and Vice Chair for Administration, Chief of Surgical Oncology, and Medical Director of the UTMB Cancer Center, with an adjunct appointment at The University of Texas MD Anderson Cancer Center. An internationally recognized leader in breast surgical oncology, Dr. Klimberg is known for pioneering innovations in breast cancer surgery, including the axillary reverse mapping (ARM) technique for lymphedema prevention, oncoplastic and minimally invasive breast surgery, and novel approaches to breast cancer diagnosis and treatment. She has served as president of the Association of Academic Surgeons, the Society of Surgical Oncology, the American Society of Breast Surgeons, and the Southern Surgical Association, and currently serves in leadership roles with the American Board of Surgery, the American Board of Complex Surgical Oncology, and the American Board of Plastic Surgery. Dr. Klimberg has authored more than 350 peer-reviewed publications, 75 book chapters, and 17 books, and holds nine patents related to innovations in breast cancer surgery. William J. Gradishar, M.D., is the Betsy Bramsen Professor of Breast Oncology in the Division of Hematology and Medical Oncology at Northwestern University Feinberg School of Medicine, Director of the Maggie Daley Center for Women's Cancer Care, and a member of the Robert H. Lurie Comprehensive Cancer Center. An internationally recognized expert in breast cancer, his research focuses on the development of novel therapeutics for the treatment of breast cancer. Dr. Gradishar has held numerous leadership roles within the American Society of Clinical Oncology (ASCO), the Eastern Cooperative Oncology Group (ECOG), and the National Comprehensive Cancer Network (NCCN), where he has served on the Breast Cancer Guidelines and Breast Cancer Prevention Panels. He also serves as a consultant to the U.S. Food and Drug Administration's Oncology Drug Advisory Committee and has contributed extensively to the field through service on editorial boards of leading oncology journals.

"This book is a standard reference text on breast diseases. The previous version was published in 2017, and rapid advances in the field amply justify this new sixth edition. Purchase of the print book includes access to an electronic version, which is fully searchable and annotatable, and includes selected videos." -©Doody’s Review Service, 2023, Carol Scott-Conner, MD, PhD, MBA (University of Iowa Hospitals and Clinics) Doody's Score: 5 Stars!

• SECTION I History of the Therapy of Breast Cancer1. The History of the Therapy for Breast Cancer2. History of Surgical Clinical Trials and Cooperative Group Trials3. Important Trials of the Last DecadeSECTION II Anatomy and Physiology of the Normal and Lactating Breast4. Anatomy of the Breast, Axilla, Chest Wall, and Related Metastatic Sites5. Breast Physiology: Normal and Abnormal Development and Function6. Discharges and Secretions of the NippleSECTION III Natural History, Epidemiology, Genetics, and Syndromes of the Breast7. Epidemiology of Breast Cancer8. Carcinogenesis of Breast Cancer9. Risk Reduction for Developing Breast Cancer10. Breast Cancer Genetics: Syndromes, Genes, Pathology, Counseling, Testing, and TreatmentSECTION IV Screening and Diagnosis of the Breast Patient11. Clinical Encounter With the Patient12. Breast Cancer Screening13. Breast Cancer Diagnosis and Techniques for BiopsySECTION V Benign and Premalignant Lesions14. Etiology and Management of Benign Breast Disease15. Mastitis and Breast Abscess16. Gynecomastia17. High-Risk and Premalignant Lesions of the BreastSECTION VI Pathology of Malignant Lesions18. Disorders of the Skin19. Ductal Carcinoma In Situ20. Infiltrating Carcinomas of the Breast21. Biomarkers22. Fibroepithelial Tumors and Hamartomas23. Lymphomas of the Breast24. Mesenchymal Neoplasms of the Breast25. Unusual and Rare Tumors of the BreastSECTION VII Prognostic Factors for Breast Cancer26. Clinical Prognosis and Staging of Breast Cancer27. Molecular Biomarkers for Breast Cancer Prognosis28. Examining Domestic and International Disparities in Breast Cancer Screening, Treatment, and OutcomesSECTION VIII Surgical Techniques of the Breast29. Management of Lobular Neoplasia and Ductal Carcinoma In Situ30. General Principles of Mastectomy: From Halsted Radical Mastectomy and Modified Radical Mastectomy to Total (Simple) Mastectomy31. Breast Conservation Therapy for Invasive Breast Cancer32. Intraoperative Evaluation of Surgical Margins in Breast-Conserving Therapy33. Lymphatic Mapping and Sentinel Lymphadenectomy for Breast Cancer34. Lymphatic Mapping and Targeted Axillary Dissection Procedure After Neoadjuvant Chemotherapy35. Therapeutic Value of Axillary Node Dissection36. Lymphedema Prevention and Treatment: Axillary Reverse Mapping, LYMPHA, Lymph Node Transfer, and Other Surgical Techniques37. Wound Care and Complications of Mastectomy38. Pain Management of the Breast Cancer Surgery PatientSECTION IX Oncoplastic Breast Surgery and Reconstruction39. Optimizing Cosmetic Outcomes for Breast Surgery40. Upper Hemisphere Oncoplastic Surgery41. Oncoplastic Techniques for the Lower Hemisphere of the Breast42. Oncoplastic Breast Reconstruction: Extreme Oncoplasty and Split Reduction Techniques43. Nipple Skin-Sparing Mastectomy44. Breast ReconstructionSECTION X Adjuvant Therapy for Stages 0, I, and II Breast Cancer45. Radiotherapy and Regional Nodes46. Postmastectomy Radiation Therapy47. Breast-Conserving Therapy for Invasive Breast Cancers48. Partial Breast Irradiation: Accelerated and Intraoperative49. Radiation Complications and Their Management50. Radiation Therapy for Locally Advanced Breast Cancer: Historical Review to Current Approaches51. Systemic Therapy of Hormone-Sensitive HER2-Negative Breast Cancer: Adjuvant and Neoadjuvant52. Adjuvant and Neoadjuvant Systemic Therapies for Triple-Negative Breast Cancer53. Adjuvant and Neoadjuvant HER2 TherapySECTION XI Management of Advanced Local, Regional, and Systemic Disease54. Surgical Procedures for Advanced Local and Regional Malignancies of the Breast55. Management of the Intact Breast Primary in the Setting of Metastatic Disease56. Locoregional Recurrence of Breast Cancer57. Locally Advanced and Inflammatory Breast Cancer58. Clinical Implications of Occult Systemic Micrometastatic Breast Cancer59. Management of Breast Cancer Solitary Metastases60. Management of Bone Metastases in Breast Cancer61. Chemotherapy and HER2-Directed Therapy for Metastatic Breast Cancer62. Endocrine Therapy for Late-Stage and Metastatic Breast Cancer63. Immunological Approaches to Breast Cancer Therapy64. Diagnosis and Management of Pleural Metastases and Malignant Effusion in Breast Cancer65. Management of Central Nervous System Metastases in Breast CancerSECTION XII Special Presentations of Breast Cancer66. Bilateral Breast Cancer67. Male Breast Cancer68. Local Recurrence, the Augmented Breast, and the Contralateral Breast69. Carcinoma of the Breast in Pregnancy and Lactation70. Unknown Primary Presenting With Axillary LymphadenopathySECTION XIII Survivorship, Follow-Up Care, and Rehabilitation of the Breast Cancer Patient71. Creating a Breast Cancer Survivorship Plan and Clinic72. General Considerations for Follow-Up73. Bone-Modifying Agents in Early Breast Cancer74. Fertility Preservation for Women With Breast Cancer75. Quality Measures and Performance Improvement for Breast Cancer Surgery76. Lymphedema in the Postsurgical Patient: Pathophysiology and Nonoperative Management77. Management of Menopause in Breast Cancer Survivors78. Rehabilitation79. Psychosocial Consequences and Lifestyle Interventions