Living Donor Organ Transplantation

Dr. Rainer W. G. Gruessner, MD, FACS, FICS, is Professor of Surgery at SUNY Downstate Health Sciences University. He formerly served as Chairmen of the Departments of Surgery at the University of Zurich, University of Arizona, and State University of New York. Dr. Gruessner is a nationally renowned surgeon and clinical innovator who has developed new surgical techniques for intestinal, pancreas, and liver transplants. He is prolific academic, a committed educator, and successful mentor to surgical and transplant faculty, residents and fellows. Dr. Gruessner’s academic accomplishments include more than 700 published manuscripts, review articles, book chapters, and published abstracts. Dr. Gruessner has been an invited speaker at over 170 institutions and meetings worldwide. He’s (co-) edited five textbooks: the standard textbooks on Transplantation of the Pancreas, Living Donor Transplantation, and Robotic Surgery and serving as senior editor of a textbook on Transplantation, Bioengineering and Regeneration of the Endocrine Pancreas and a textbook on Technological Advances in Surgery, Trauma and Critical Care. He has served as PI and co-investigator on over 20 research projects and clinical trials, supported by industry, foundations, and the NIH. Dr. Gruessner is a member of over 20 national and international professional societies, has organized many international congresses, is an editorial board member for about 10 journals and has served on many professional and societal committees. In 2019, he received the Richard C. Lillehei award from the International Pancreas and Islet Association (IPITA) for his lifetime achievements in the field of pancreas transplantation. Enrico Benedetti, MD, FACS, Warren H. Cole Chair in Surgery, Professor and Head of the Department of Surgery and Medical Director, Abdominal Organ Transplant Program at the University of Illinois at Chicago. Enrico Benedetti was born in Perugia, Italy, on Oct. 3, 1960. Dr. Benedetti graduated cum laude from the medical school in the University of Florence in 1985 and completed a surgical residency at the same university by 1989. In 1989, he moved to Chicago to start a United States surgery residency at the University of Illinois at Chicago, which he completed in 1993. Dr. Benedetti earned a fellowship in transplant surgery at the University of Minnesota. Since 1994, Dr. Benedetti has been a transplant surgeon at the University of Illinois. He started as an Assistant Professor of Surgery and rose through the ranks first to Associate Professor in 1999 and then to Professor in 2005. Dr. Benedetti is currently the Head of Department of Surgery and the Director of the Abdominal Organ Transplant Program at the University of Illinois at Chicago. Dr. Benedetti is also the recipient of the Joseph Cardinal Bernardin Humanitarian of the Year Award. Dr. Benedetti has published more than 300 articles and more than 30 book chapters and is the editor of the seminal book, “Living Donor Organ Transplantation.” Included among his many surgical accomplishments are: • The first successful combined coronary artery bypass and liver transplant worldwide• The first robotic donor nephrectomy for living donor kidney transplant worldwide in 2000• The first combined living donor liver/bowel transplant from adult to an infant worldwide in 2003 • The first robotic combined kidney/pancreas procurement for living donor kidney/pancreas transplant worldwide in 2005• The largest series worldwide of living donor intestinal transplantation (32 of a total of 47 cases done in the world) • First robotic kidney transplant in obese recipient in 2009

• PART I. GENERAL ASPECTS OF LIVING DONOR ORGAN TRANSPLANTATION 1. Introduction and Rationale 2. Cultural Differences In Living Organ Donation 3. Ethical and Legal Issues 4. Donor Counseling and Consent 5. Nondirected Donors 6. General Aspects of Living Donor Organ Transplantation: Social IssuesPART II. PAID LEGAL AND ILLEGAL ORGAN DONATION 7. Current Financial Incentives 8. Paid Legal Organ Donation 9. Challenges of Paid Organ Donation for Public Health Care Policy 10. Who’s Got the Knife? The Role of Surgeons in Transplant TraffickingPART III. THE ROLE OF SOCIAL MEDIA 11. Living Donor Organ Transplantation: The Role of Public Solicitation 12. The Impact of the Internet and Social Media on Paid Legal and Illegal Organ DonationPART IV. ORGAN-SPECIFIC ASPECTS OF LIVING DONOR ABDOMINAL ORGAN TRANSPLANTATION SECTION I. KIDNEY TRANSPLANTATION 13. Kidney Transplantation: Personal Reflections 14. History of Living Donor Kidney Transplantation 15. Kidney Transplantation: Geographical Differences 16. Preemptive Living Transplantation: The Ideal Therapeutic Modality for End-Stage Renal Disease 17. Kidney Transplantation: The Donor 18. Kidney Transplantation: The Recipient 19. Kidney Transplantation: Cost Analysis SECTION II. PANCREAS TRANSPLANTATION 20. History of and Rationale for Pancreas Transplantation 21. Pancreas Transplantation: The Donor 22. Pancreas Transplantation: The Recipient 23. The Asian Experience 24. International Pancreas Registry Report (IPTR) and Long-Term Outcome 25. Islet Autotransplantation after Pancreatectomy 26. Islet Transplantation Using Living Donors SECTION III. LIVER TRANSPLANTATION 27. Personal Reflections and History of Living Donor Liver Transplantation 28. The Impact of the A2all Study 29. Regional Variations in the U.S. Living Donor Experience 30. Institutional Needs for Living Donor Liver Transplantation 31. Role of Split Liver Transplantation from Deceased Donors: Lessons Learned 32. Liver Regeneration 33. Living Donor Liver Transplantation: The Donor 34. Liver Transplantation: The Recipient 35. Liver Transplantation: Cost Analysis SECTION IV. INTESTINAL TRANSPLANTATION 36. History of Living Donor Intestinal Transplantation 37. Indications for Living Donor Intestinal (and Liver) Transplantation 38. Intestinal Transplantation – The Donor 39. Intestinal Transplantation – The Recipient SECTION V. UTERUS TRANSPLANTATION 40. History of Living Donor Uterus Transplantation 41. Uterus Transplantation - The Donor 42. Uterus Transplantation - The RecipientPART V. FUTURE DEVELOPMENTS AND ALTERNATIVES TO LIVING DONOR TRANSPLANTATION 43. Dual-Organ Donation and Transplantation 44. Use of Living Donors for HIV-Positive Transplant Candidates 45. New Immunosuppressive Protocols 46. Strategies to Induce Tolerance 47. Xenotransplantation 48. Gene Therapy 49. Organogenesis and related approaches for organ replacement 50. Consensus Conferences on Living Donor Organ Transplantation 51. Impact of the Coronavirus Pandemic on Living Donor Organ Transplantation