Immunology of Recurrent Pregnancy Loss and Implantation Failure

Häftad, Engelska, 2022

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Beskrivning

Immunology of Recurrent Pregnancy Loss provides doctors and immunologists with the information they need to help couples who experience recurrent pregnancy losses. Sections cover unexplained infertility, repeated in vitro fertilization, embryo transfer failures, history of second or third trimester pregnancy losses of unknown cause, or pregnancy with a history of or active autoimmune and/or alloimmune disease.� Reproductive failure (RF), including recurrent pregnancy losses (RPL) and repeated implantation failures (RIF) is rather a syndrome than a disease caused by multiple etiologies, such as anatomical, endocrine, genetic, infectious, immunological, thrombotic and unexplained etiologies, hence this book strives to present the latest information.

In 27 chapters, divided in 5 sections, the book introduces the current update of reproductive immunology topics in RF and provides systematic diagnostic guidelines, systemic and immune etiologies and therapeutic approaches.

Provides detailed immunological background for understanding the etiology and management of reproduction failure
Evaluates various immunological factors involved in the pathogenesis and management of reproduction failure
Gives insights into various immunological and therapeutic approaches for reproduction failure

Produktinformation

Utgivningsdatum:2022-07-07
Mått:191 x 235 x 26 mm
Vikt:930 g
Format:Häftad
Språk:Engelska
Serie:Reproductive Immunology
Antal sidor:456
Förlag:Elsevier Science
ISBN:9780323908054

Utforska kategorier

Onkologi inom Medicin

Mer om författaren

Joanne Kwak-Kim Reproductive Medicine, Department of Obstetrics and Gynecology, Chicago Medical School at Rosalind Franklin University of Medicine and Science, Vernon Hills, IL, USA Department of Microbiology and Immunology, Chicago Medical School at Rosalind Franklin University of Medicine and Science, North Chicago, IL, USA Corresponding author at: Reproductive Medicine, Department of Obstetrics and Gynecology, Department of Microbiology and Immunology, Chicago Medical School at Rosalind Franklin University of Medicine and Science, 830 West End Court, Suite 400, Vernon Hills, IL, 60061, USA. Fax: + 1 847 327 6129 Dr. Kwak has the highest scholarly output on this subject. A pioneer in the field of Reproductive Immunology, Dr. Kwak-Kim has devoted more than 25 years of her career to Reproductive Immunology research and continues to do so. She is focusing her research on unravelling the role of the immune system in pregnancy and pregnancy loss and developing treatment plans that help women maintain successful pregnancies. While attempting pregnancy, Dr Kwak-Kim and her staff co-manage patients along with their reproductive endocrinologist or primary gynaecologist. Once pregnancy occurs, co-management continues with their obstetricians or high-risk obstetricians.

Innehållsförteckning

Section 1. IntroductionSection 2. RPL of immune etiologies1. Autoimmune etiologies focusing antiphospholipid antibody2. ANA related conditions3. Celiac disease and RPL/RIF4. NK cell pathology and RF; NK cell level, NK cell cytotoxicity and KIR/HLA-C5. Th cell pathology and RPL; TH1/Th2, Treg/Th17, and others6. B cell pathology and RPL; B cell7. Mast cell pathology and RPL8. Endometrial pathology and RPL9. Infectious diseases that can flare immune responses; Lyme’s disease, COVID-19, etc.10. Thrombophilic pathology and RPL11. Alloimmune conditions (NAIT, Rh sensitization)Section 3. Repeated implantation failures of immune etiologies12. Autoimmune etiologies focusing antiphospholipid antibody13. NK cell pathology and RIF14. Th cell pathology and RIF15. B cell pathology and RIF; Allergy, Asthma and infertility16. Endometrial pathology and RIF17. Thrombophilic condition and RIFSection 4. Systemic immune etiologies for RIF/RPL18. Ovarian pathology and RIF/RPL19. Endometriosis and RIF/RPL20. ART and RIF/RPL21. Hormonal/metabolic diseases that can cause proinflammatory condition: autoimmune thyroiditis, PCOS, DM, vitamin D deficiency, and homocysteinemia22. Stress induced immune flare in women with RFSection 5. Treatment modalities23. Immunotherapy24. Anti-coagulant25. Hormonal/metabolic26. Reproductive supplements27. Vitamins: Vitamin C, D, E, Folic acid, vitamin B12, selenium, zinc28. Ovulation boost; DHEA, CoQ10, myoinositol, acaiberry, MACA, ALA, NAC, melatonin29. Anti-inflammatory- LDN (low dose naltrexone), curcumin30. Chinese medicine: Zishen Yutai pill, Shoutai pill