Emeritus Professor, Dr Gundu H. R. Rao has spent forty years as a faculty member of Laboratory Medicine and Pathology at the University of Minnesota. He was the Director of Thrombosis Research at the Lillehei Heart Institute and adjunct faculty of the Institute for Engineering Medicine as well as Anesthesiology. For four decades, he conducted research on morphology, ultrastructure, biochemistry, physiology, and pharmacology of blood platelets. During these years of research, he presented his work at various national and international conferences as well as published his work in over 300 peer reviewed journals. In early 1990, he obtained a research grant from the International Society on Thrombosis and Hemostasis (ISTH, USA), and started a professional society, ‘South Asian Society on Atherosclerosis and Thrombosis’ at the University of Minnesota. He organized international conferences on topics associated with thrombosis and hemostasis in India every other year from 1994. He also has edited and published books on topics related to this area of public interest. Undurti N. Das is an M.D. in Internal Medicine from Osmania Medical College, Hyderabad, India; a Fellow of the National Academy of Medical Sciences, India, and Shanti Swaroop Bhatnagar prize awardee. Apart from clinical work, he is researching the role of polyunsaturated fatty acids, cytokines, nitric oxide, free radicals, and anti-oxidants in cancer, inflammation, metabolic syndrome, schizophrenia, sepsis, rheumatological conditions and autisms. His current interests include the epidemiological and molecular aspects of autism, diabetes mellitus, hypertension, cardiovascular diseases and metabolic syndrome. Dr. Das was formerly scientist at Efamol Research Institute, Kentville, Canada; Professor of Medicine at Nizam’s Institute of Medical Sciences, Hyderabad, India and Research Professor of Surgery and Nutrition at SUNY (State University of New York) Upstate Medical University, Syracuse, USA. At present, he is the Chairman and Research Director of UND Life Sciences LLC, USA, and serves as a consultant to both Indian and USA based biotech and pharmaceutical companies. Undurti Das is the Founding Editor of the international journal: Lipids in Health and Disease; and serves on the editorial board of another 10 international journals. Dr Das has more than 500 international publications and has been awarded 5 USA patents.

• PrefaceForewordI. Cardiometabolic Diseases1. Cardiometabolic Diseases: Risk Factors and Novel Approaches for the Management of Risks.2. The Chennai Urban Rural Epidemiology Study (CURES) – A Compendium of type 2 diabetes in urban Asian Indians: Lessons Learnt3. Prevalence of diabetes in urban and rural India-ICMR-INDIAB study4. Burden of cardiometabolic syndrome in children.5. Diabetes care program with limited resources6. Type 2 diabetes: A Modern-Day Avatar of Malnutrition Related Diabetes7. Understanding double burden of malnutrition from a DOHaD perspective: Review of Mysore Cohorts8. Diabetes care for the bottom of the socioeconomic pyramid: Four decades of science, medicine, creativity and empathy (Samatvam India model)9. Pathophysiology of Cardiorenal Syndrome10. Evidence of Clinical Trials of Cardiac Outcomes on Renal DiseaseII. CMDs: Cellular Mechanisms11. Periodontal Disease and Occlusive Atherosclerotic Vascular Diseases12. Insulin is a cytoprotective molecule13. Galectin-3 and its associated molecular partners in the emergence and progression of cardiometabolic disorders14. Vascular Dysfunction in Obesity and Diabetes: Role of ncRNA15. In-Cardiome: Integrated knowledge base for CAD Enabling Translational Research16. Are Southeast Asians Cushingoid? A molecular explanation for the high incidence of metabolicsyndrome17. Occlusive Arterial Vascular Diseases: Cellular and Molecular Mechanisms18. Why is exercise beneficial?III. Risk Factors and Prevention19. Hypothyroidism, Diabetes and Cardiovascular disease20. Adipose Tissue and Dyslipidemia: Insight from Lipodystrophy Syndromes - why fat is not the enemy in Cardiometabolic disease21. Risk Factors for Ischemic Stroke22. Blood pressure lowering in kidney disease23. Diabetic Peripheral Vascular Disease.24. Limb salvage among people with Diabetes.25. The role of Blood Viscosity in Health and Disease26. Hypertension and Acute coronary Syndromes27. Hypertension and Stroke: An Update28. Prevention of Childhood Obesity and Diabetes : An Indian Context29. Screening of cardiovascular risk in school children and adolescents30. Diabetes Pandemic in Manitoba: An Update on Prevention of New Cases31. Type 1 diabetes risk factors and prevention32. Cardiovascular Risk Stratification in Indian Subjects: Lessons Learned and the Way Forward33. Measurement of Carotid Plaque Burden.34. Role of Metabolic State, Hemodynamics, and Neuromonitoring in Cardiac Arrest Survival and Neurological Outcome35. Secondary Stroke Prevention36. Acute Ischemic Stroke: Diagnosis and Endovascular Management37. Cardiometabolic Diseases - Recent Advance in Antithrombotic and Thrombolytic Therapies38. Management of Cardio-Metabolic Diseases: A Clinician’s Perspective39. Prevention of Cardiovascular Diseases - From Science to Public Health Action

Emeritus Professor, Dr Gundu H. R. Rao has spent forty years as a faculty member of Laboratory Medicine and Pathology at the University of Minnesota. He was the Director of Thrombosis Research at the Lillehei Heart Institute and adjunct faculty of the Institute for Engineering Medicine as well as Anesthesiology. For four decades, he conducted research on morphology, ultrastructure, biochemistry, physiology, and pharmacology of blood platelets. During these years of research, he presented his work at various national and international conferences as well as published his work in over 300 peer reviewed journals. In early 1990, he obtained a research grant from the International Society on Thrombosis and Hemostasis (ISTH, USA), and started a professional society, ‘South Asian Society on Atherosclerosis and Thrombosis’ at the University of Minnesota. He organized international conferences on topics associated with thrombosis and hemostasis in India every other year from 1994. He also has edited and published books on topics related to this area of public interest. Undurti N. Das is an M.D. in Internal Medicine from Osmania Medical College, Hyderabad, India; a Fellow of the National Academy of Medical Sciences, India, and Shanti Swaroop Bhatnagar prize awardee. Apart from clinical work, he is researching the role of polyunsaturated fatty acids, cytokines, nitric oxide, free radicals, and anti-oxidants in cancer, inflammation, metabolic syndrome, schizophrenia, sepsis, rheumatological conditions and autisms. His current interests include the epidemiological and molecular aspects of autism, diabetes mellitus, hypertension, cardiovascular diseases and metabolic syndrome. Dr. Das was formerly scientist at Efamol Research Institute, Kentville, Canada; Professor of Medicine at Nizam’s Institute of Medical Sciences, Hyderabad, India and Research Professor of Surgery and Nutrition at SUNY (State University of New York) Upstate Medical University, Syracuse, USA. At present, he is the Chairman and Research Director of UND Life Sciences LLC, USA, and serves as a consultant to both Indian and USA based biotech and pharmaceutical companies. Undurti Das is the Founding Editor of the international journal: Lipids in Health and Disease; and serves on the editorial board of another 10 international journals. Dr Das has more than 500 international publications and has been awarded 5 USA patents.

• PrefaceForewordI. Cardiometabolic Diseases1. Cardiometabolic Diseases: Risk Factors and Novel Approaches for the Management of Risks.2. The Chennai Urban Rural Epidemiology Study (CURES) – A Compendium of type 2 diabetes in urban Asian Indians: Lessons Learnt3. Prevalence of diabetes in urban and rural India-ICMR-INDIAB study4. Burden of cardiometabolic syndrome in children.5. Diabetes care program with limited resources6. Type 2 diabetes: A Modern-Day Avatar of Malnutrition Related Diabetes7. Understanding double burden of malnutrition from a DOHaD perspective: Review of Mysore Cohorts8. Diabetes care for the bottom of the socioeconomic pyramid: Four decades of science, medicine, creativity and empathy (Samatvam India model)9. Pathophysiology of Cardiorenal Syndrome10. Evidence of Clinical Trials of Cardiac Outcomes on Renal DiseaseII. CMDs: Cellular Mechanisms11. Periodontal Disease and Occlusive Atherosclerotic Vascular Diseases12. Insulin is a cytoprotective molecule13. Galectin-3 and its associated molecular partners in the emergence and progression of cardiometabolic disorders14. Vascular Dysfunction in Obesity and Diabetes: Role of ncRNA15. In-Cardiome: Integrated knowledge base for CAD Enabling Translational Research16. Are Southeast Asians Cushingoid? A molecular explanation for the high incidence of metabolicsyndrome17. Occlusive Arterial Vascular Diseases: Cellular and Molecular Mechanisms18. Why is exercise beneficial?III. Risk Factors and Prevention19. Hypothyroidism, Diabetes and Cardiovascular disease20. Adipose Tissue and Dyslipidemia: Insight from Lipodystrophy Syndromes - why fat is not the enemy in Cardiometabolic disease21. Risk Factors for Ischemic Stroke22. Blood pressure lowering in kidney disease23. Diabetic Peripheral Vascular Disease.24. Limb salvage among people with Diabetes.25. The role of Blood Viscosity in Health and Disease26. Hypertension and Acute coronary Syndromes27. Hypertension and Stroke: An Update28. Prevention of Childhood Obesity and Diabetes : An Indian Context29. Screening of cardiovascular risk in school children and adolescents30. Diabetes Pandemic in Manitoba: An Update on Prevention of New Cases31. Type 1 diabetes risk factors and prevention32. Cardiovascular Risk Stratification in Indian Subjects: Lessons Learned and the Way Forward33. Measurement of Carotid Plaque Burden.34. Role of Metabolic State, Hemodynamics, and Neuromonitoring in Cardiac Arrest Survival and Neurological Outcome35. Secondary Stroke Prevention36. Acute Ischemic Stroke: Diagnosis and Endovascular Management37. Cardiometabolic Diseases - Recent Advance in Antithrombotic and Thrombolytic Therapies38. Management of Cardio-Metabolic Diseases: A Clinician’s Perspective39. Prevention of Cardiovascular Diseases - From Science to Public Health Action

Emeritus Professor, Dr Gundu H. R. Rao has spent forty years as a faculty member of Laboratory Medicine and Pathology at the University of Minnesota. He was the Director of Thrombosis Research at the Lillehei Heart Institute and adjunct faculty of the Institute for Engineering Medicine as well as Anesthesiology. For four decades, he conducted research on morphology, ultrastructure, biochemistry, physiology, and pharmacology of blood platelets. During these years of research, he presented his work at various national and international conferences as well as published his work in over 300 peer reviewed journals. In early 1990, he obtained a research grant from the International Society on Thrombosis and Hemostasis (ISTH, USA), and started a professional society, ‘South Asian Society on Atherosclerosis and Thrombosis’ at the University of Minnesota. He organized international conferences on topics associated with thrombosis and hemostasis in India every other year from 1994. He also has edited and published books on topics related to this area of public interest. Undurti N. Das is an M.D. in Internal Medicine from Osmania Medical College, Hyderabad, India; a Fellow of the National Academy of Medical Sciences, India, and Shanti Swaroop Bhatnagar prize awardee. Apart from clinical work, he is researching the role of polyunsaturated fatty acids, cytokines, nitric oxide, free radicals, and anti-oxidants in cancer, inflammation, metabolic syndrome, schizophrenia, sepsis, rheumatological conditions and autisms. His current interests include the epidemiological and molecular aspects of autism, diabetes mellitus, hypertension, cardiovascular diseases and metabolic syndrome. Dr. Das was formerly scientist at Efamol Research Institute, Kentville, Canada; Professor of Medicine at Nizam’s Institute of Medical Sciences, Hyderabad, India and Research Professor of Surgery and Nutrition at SUNY (State University of New York) Upstate Medical University, Syracuse, USA. At present, he is the Chairman and Research Director of UND Life Sciences LLC, USA, and serves as a consultant to both Indian and USA based biotech and pharmaceutical companies. Undurti Das is the Founding Editor of the international journal: Lipids in Health and Disease; and serves on the editorial board of another 10 international journals. Dr Das has more than 500 international publications and has been awarded 5 USA patents.

• PrefaceForewordI. Cardiometabolic Diseases1. Cardiometabolic Diseases: Risk Factors and Novel Approaches for the Management of Risks.2. The Chennai Urban Rural Epidemiology Study (CURES) – A Compendium of type 2 diabetes in urban Asian Indians: Lessons Learnt3. Prevalence of diabetes in urban and rural India-ICMR-INDIAB study4. Burden of cardiometabolic syndrome in children.5. Diabetes care program with limited resources6. Type 2 diabetes: A Modern-Day Avatar of Malnutrition Related Diabetes7. Understanding double burden of malnutrition from a DOHaD perspective: Review of Mysore Cohorts8. Diabetes care for the bottom of the socioeconomic pyramid: Four decades of science, medicine, creativity and empathy (Samatvam India model)9. Pathophysiology of Cardiorenal Syndrome10. Evidence of Clinical Trials of Cardiac Outcomes on Renal DiseaseII. CMDs: Cellular Mechanisms11. Periodontal Disease and Occlusive Atherosclerotic Vascular Diseases12. Insulin is a cytoprotective molecule13. Galectin-3 and its associated molecular partners in the emergence and progression of cardiometabolic disorders14. Vascular Dysfunction in Obesity and Diabetes: Role of ncRNA15. In-Cardiome: Integrated knowledge base for CAD Enabling Translational Research16. Are Southeast Asians Cushingoid? A molecular explanation for the high incidence of metabolicsyndrome17. Occlusive Arterial Vascular Diseases: Cellular and Molecular Mechanisms18. Why is exercise beneficial?III. Risk Factors and Prevention19. Hypothyroidism, Diabetes and Cardiovascular disease20. Adipose Tissue and Dyslipidemia: Insight from Lipodystrophy Syndromes - why fat is not the enemy in Cardiometabolic disease21. Risk Factors for Ischemic Stroke22. Blood pressure lowering in kidney disease23. Diabetic Peripheral Vascular Disease.24. Limb salvage among people with Diabetes.25. The role of Blood Viscosity in Health and Disease26. Hypertension and Acute coronary Syndromes27. Hypertension and Stroke: An Update28. Prevention of Childhood Obesity and Diabetes : An Indian Context29. Screening of cardiovascular risk in school children and adolescents30. Diabetes Pandemic in Manitoba: An Update on Prevention of New Cases31. Type 1 diabetes risk factors and prevention32. Cardiovascular Risk Stratification in Indian Subjects: Lessons Learned and the Way Forward33. Measurement of Carotid Plaque Burden.34. Role of Metabolic State, Hemodynamics, and Neuromonitoring in Cardiac Arrest Survival and Neurological Outcome35. Secondary Stroke Prevention36. Acute Ischemic Stroke: Diagnosis and Endovascular Management37. Cardiometabolic Diseases - Recent Advance in Antithrombotic and Thrombolytic Therapies38. Management of Cardio-Metabolic Diseases: A Clinician’s Perspective39. Prevention of Cardiovascular Diseases - From Science to Public Health Action