Director John E. Hall works at the Mississippi Center for Obesity Research, Department of Physiology and Biophysics, Jackson, Mississippi. Michael E. Hall is Associate Professor of Medicine, Division of Cardiovascular Diseases, Director, Clinical and Population Science, Mississippi Center for Clinical and Translational Research, Jackson, Mississippi.

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• UNIT I: Introduction to Physiology: The Cell and General Physiology 1. Functional Organization of the Human Body and Control of the "Internal Environment" 2. The Cell and Its Functions 3. Genetic Control of Protein Synthesis, Cell Function, and Cell Reproduction UNIT II: Membrane Physiology, Nerve, and Muscle 4. Transport of Substances Through Cell Membranes 5. Membrane Potentials and Action Potentials 6. Contraction of Skeletal Muscle 7. Excitation of Skeletal Muscle: Neuromuscular Transmission and Excitation-Contraction Coupling 8. Excitation and Contraction of Smooth Muscle UNIT III: The Heart 9. Cardiac Muscle; The Heart as a Pump and Function of the Heart Valves 10. Rhythmical Excitation of the Heart 11. Fundamentals of Electrocardiography 12. Electrocardiographic Interpretation of Cardiac Muscle and Coronary Blood Flow Abnormalities: Vectorial Analysis 13. Cardiac Arrhythmias and Their Electrocardiographic Interpretation UNIT IV: The Circulation 14. Overview of the Circulation: Pressure, Flow, and Resistance 15. Vascular Distensibility and Functions of the Arterial and Venous Systems 16. The Microcirculation and Lymphatic System: Capillary Fluid Exchange, Interstitial Fluid, and Lymph Flow 17. Local and Humoral Control of Tissue Blood Flow 18. Nervous Regulation of the Circulation and Rapid Control of Arterial Pressure 19. Role of the Kidneys in Long-Term Control of Arterial Pressure and in Hypertension: The Integrated System for Arterial Pressure Regulation 20. Cardiac Output, Venous Return, and Their Regulation 21. Muscle Blood Flow and Cardiac Output During Exercise; The Coronary Circulation and Ischemic Heart Disease 22. Heart Failure 23. Heart Valves and Heart Sounds; Valvular and Congenital Heart Defects 24. Circulatory Shock and Its Treatment UNIT V: The Body Fluids and Kidneys 25. Regulation of Body Fluid Compartments: Extracellular and Intracellular Fluids; Edema 26. The Urinary System: Functional Anatomy and Urine Formation By the Kidneys 27. Glomerular Filtration, Renal Blood Flow, and Their Control 28. Renal Tubular Reabsorption and Secretion 29. Urine Concentration and Dilution; Regulation of Extracellular Fluid Osmolarity and Sodium Concentration 30. Renal Regulation of Potassium, Calcium, Phosphate, and Magnesium; Integration of Renal Mechanisms for Control of Blood Volume and Extracellular Fluid Volume 31. Acid-Base Regulation 32. Diuretics and Kidney Diseases UNIT VI: Blood Cells, Immunity, and Blood Coagulation 33. Red Blood Cells, Anemia, and Polycythemia 34. Resistance of the Body to Infection: I. Leukocytes, Granulocytes, the Monocyte-Macrophage System, and Inflammation 35. Resistance of the Body to Infection: II. Immunity and Allergy 36. Blood Types, Transfusion, and Tissue and Organ Transplantation 37. Hemostasis and Blood Coagulation UNIT VII: Respiration 38. Pulmonary Ventilation 39. Pulmonary Circulation, Pulmonary Edema, and Pleural Fluid 40. Principles of Gas Exchange; Diffusion of Oxygen and Carbon Dioxide Through Respiratory Membranes 41. Transport of Oxygen and Carbon Dioxide in Blood and Tissue Fluids 42. Regulation of Respiration 43. Respiratory Insufficiency-Pathophysiology, Diagnosis, Oxygen Therapy UNIT VIII: Aviation, Space, and Deep-Sea Diving Physiology 44. Aviation, High Altitude, and Space Physiology 45. Physiology of Deep-Sea Diving and Other Hyperbaric Conditions UNIT IX: The Nervous System: A. General Principles and Sensory Physiology 46. Organization of the Nervous System, Basic Functions of Synapses and Neurotransmitters 47. Sensory Receptors and Neuronal Circuits for Processing Information 48. Somatic Sensations: I. General Organization, Tactile and Position Senses 49. Somatic Sensations: II. Pain, Headache, and Thermal Sensations UNIT X: The Nervous System: B. The Special Senses 50. The Eye: I. Optics of Vision 51. The Eye: II. Receptor and Neural Function of the Retina 52. The Eye: III. Central Neurophysiology of Vision 53. The Sense of Hearing 54. The Chemical Senses-Taste and Smell UNIT XI: The Nervous System: C. Motor and Integrative Neurophysiology 55. Spinal Cord Motor Functions; The Cord Reflexes 56. Cortical and Brain Stem Control of Motor Function 57. Cerebellum and Basal Ganglia Contributions to Overall Motor Control 58. Cerebral Cortex, Intellectual Functions of the Brain, Learning, and Memory 59. The Limbic System and the Hypothalamus-Behavioral and Motivational Mechanisms of the Brain 60. States of Brain Activity-Sleep, Brain Waves, Epilepsy, Psychoses, and Dementia 61. The Autonomic Nervous System and the Adrenal Medulla 62. Cerebral Blood Flow, Cerebrospinal Fluid, and Brain Metabolism UNIT XII: Gastrointestinal Physiology 63. General Principles of Gastrointestinal Function-Motility, Nervous and Hormonal Control, Blood Circulation, and Microbiota 64. Propulsion and Mixing of Food in the Alimentary Tract 65. Secretory Functions of the Alimentary Tract 66. Digestion and Absorption in the Gastrointestinal Tract 67. Physiology of Gastrointestinal Disorders UNIT XIII: Metabolism and Temperature Regulation 68. Metabolism of Carbohydrates and Formation of Adenosine Triphosphate 69. Lipid Metabolism 70. Protein Metabolism 71. The Liver 72. Dietary Balances; Regulation of Feeding; Obesity and Starvation; Vitamins and Minerals 73. Energetics and Metabolic Rate 74. Body Temperature Regulation and Fever UNIT XIV: Endocrinology and Reproduction 75. Introduction to Endocrinology 76. Pituitary Hormones and Their Control By the Hypothalamus 77. Thyroid Metabolic Hormones 78. Adrenocortical Hormones 79. Insulin, Glucagon, and Diabetes Mellitus 80. Parathyroid Hormone, Calcitonin, Calcium and Phosphate Metabolism, Vitamin D, Bone, and Teeth 81. Reproductive and Hormonal Functions of the Male (and Function of the Pineal Gland) 82. Female Physiology Before Pregnancy and Female Hormones 83. Pregnancy and Lactation 84. Fetal and Neonatal Physiology UNIT XV: Sports Physiology 85. Sports Physiology

Director John E. Hall works at the Mississippi Center for Obesity Research, Department of Physiology and Biophysics, Jackson, Mississippi. Michael E. Hall is Associate Professor of Medicine, Division of Cardiovascular Diseases, Director, Clinical and Population Science, Mississippi Center for Clinical and Translational Research, Jackson, Mississippi.

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• UNIT I: Introduction to Physiology: The Cell and General Physiology 1. Functional Organization of the Human Body and Control of the "Internal Environment" 2. The Cell and Its Functions 3. Genetic Control of Protein Synthesis, Cell Function, and Cell Reproduction UNIT II: Membrane Physiology, Nerve, and Muscle 4. Transport of Substances Through Cell Membranes 5. Membrane Potentials and Action Potentials 6. Contraction of Skeletal Muscle 7. Excitation of Skeletal Muscle: Neuromuscular Transmission and Excitation-Contraction Coupling 8. Excitation and Contraction of Smooth Muscle UNIT III: The Heart 9. Cardiac Muscle; The Heart as a Pump and Function of the Heart Valves 10. Rhythmical Excitation of the Heart 11. Fundamentals of Electrocardiography 12. Electrocardiographic Interpretation of Cardiac Muscle and Coronary Blood Flow Abnormalities: Vectorial Analysis 13. Cardiac Arrhythmias and Their Electrocardiographic Interpretation UNIT IV: The Circulation 14. Overview of the Circulation: Pressure, Flow, and Resistance 15. Vascular Distensibility and Functions of the Arterial and Venous Systems 16. The Microcirculation and Lymphatic System: Capillary Fluid Exchange, Interstitial Fluid, and Lymph Flow 17. Local and Humoral Control of Tissue Blood Flow 18. Nervous Regulation of the Circulation and Rapid Control of Arterial Pressure 19. Role of the Kidneys in Long-Term Control of Arterial Pressure and in Hypertension: The Integrated System for Arterial Pressure Regulation 20. Cardiac Output, Venous Return, and Their Regulation 21. Muscle Blood Flow and Cardiac Output During Exercise; The Coronary Circulation and Ischemic Heart Disease 22. Heart Failure 23. Heart Valves and Heart Sounds; Valvular and Congenital Heart Defects 24. Circulatory Shock and Its Treatment UNIT V: The Body Fluids and Kidneys 25. Regulation of Body Fluid Compartments: Extracellular and Intracellular Fluids; Edema 26. The Urinary System: Functional Anatomy and Urine Formation By the Kidneys 27. Glomerular Filtration, Renal Blood Flow, and Their Control 28. Renal Tubular Reabsorption and Secretion 29. Urine Concentration and Dilution; Regulation of Extracellular Fluid Osmolarity and Sodium Concentration 30. Renal Regulation of Potassium, Calcium, Phosphate, and Magnesium; Integration of Renal Mechanisms for Control of Blood Volume and Extracellular Fluid Volume 31. Acid-Base Regulation 32. Diuretics and Kidney Diseases UNIT VI: Blood Cells, Immunity, and Blood Coagulation 33. Red Blood Cells, Anemia, and Polycythemia 34. Resistance of the Body to Infection: I. Leukocytes, Granulocytes, the Monocyte-Macrophage System, and Inflammation 35. Resistance of the Body to Infection: II. Immunity and Allergy 36. Blood Types, Transfusion, and Tissue and Organ Transplantation 37. Hemostasis and Blood Coagulation UNIT VII: Respiration 38. Pulmonary Ventilation 39. Pulmonary Circulation, Pulmonary Edema, and Pleural Fluid 40. Principles of Gas Exchange; Diffusion of Oxygen and Carbon Dioxide Through Respiratory Membranes 41. Transport of Oxygen and Carbon Dioxide in Blood and Tissue Fluids 42. Regulation of Respiration 43. Respiratory Insufficiency-Pathophysiology, Diagnosis, Oxygen Therapy UNIT VIII: Aviation, Space, and Deep-Sea Diving Physiology 44. Aviation, High Altitude, and Space Physiology 45. Physiology of Deep-Sea Diving and Other Hyperbaric Conditions UNIT IX: The Nervous System: A. General Principles and Sensory Physiology 46. Organization of the Nervous System, Basic Functions of Synapses and Neurotransmitters 47. Sensory Receptors and Neuronal Circuits for Processing Information 48. Somatic Sensations: I. General Organization, Tactile and Position Senses 49. Somatic Sensations: II. Pain, Headache, and Thermal Sensations UNIT X: The Nervous System: B. The Special Senses 50. The Eye: I. Optics of Vision 51. The Eye: II. Receptor and Neural Function of the Retina 52. The Eye: III. Central Neurophysiology of Vision 53. The Sense of Hearing 54. The Chemical Senses-Taste and Smell UNIT XI: The Nervous System: C. Motor and Integrative Neurophysiology 55. Spinal Cord Motor Functions; The Cord Reflexes 56. Cortical and Brain Stem Control of Motor Function 57. Cerebellum and Basal Ganglia Contributions to Overall Motor Control 58. Cerebral Cortex, Intellectual Functions of the Brain, Learning, and Memory 59. The Limbic System and the Hypothalamus-Behavioral and Motivational Mechanisms of the Brain 60. States of Brain Activity-Sleep, Brain Waves, Epilepsy, Psychoses, and Dementia 61. The Autonomic Nervous System and the Adrenal Medulla 62. Cerebral Blood Flow, Cerebrospinal Fluid, and Brain Metabolism UNIT XII: Gastrointestinal Physiology 63. General Principles of Gastrointestinal Function-Motility, Nervous and Hormonal Control, Blood Circulation, and Microbiota 64. Propulsion and Mixing of Food in the Alimentary Tract 65. Secretory Functions of the Alimentary Tract 66. Digestion and Absorption in the Gastrointestinal Tract 67. Physiology of Gastrointestinal Disorders UNIT XIII: Metabolism and Temperature Regulation 68. Metabolism of Carbohydrates and Formation of Adenosine Triphosphate 69. Lipid Metabolism 70. Protein Metabolism 71. The Liver 72. Dietary Balances; Regulation of Feeding; Obesity and Starvation; Vitamins and Minerals 73. Energetics and Metabolic Rate 74. Body Temperature Regulation and Fever UNIT XIV: Endocrinology and Reproduction 75. Introduction to Endocrinology 76. Pituitary Hormones and Their Control By the Hypothalamus 77. Thyroid Metabolic Hormones 78. Adrenocortical Hormones 79. Insulin, Glucagon, and Diabetes Mellitus 80. Parathyroid Hormone, Calcitonin, Calcium and Phosphate Metabolism, Vitamin D, Bone, and Teeth 81. Reproductive and Hormonal Functions of the Male (and Function of the Pineal Gland) 82. Female Physiology Before Pregnancy and Female Hormones 83. Pregnancy and Lactation 84. Fetal and Neonatal Physiology UNIT XV: Sports Physiology 85. Sports Physiology

Director John E. Hall works at the Mississippi Center for Obesity Research, Department of Physiology and Biophysics, Jackson, Mississippi. Michael E. Hall is Associate Professor of Medicine, Division of Cardiovascular Diseases, Director, Clinical and Population Science, Mississippi Center for Clinical and Translational Research, Jackson, Mississippi.

Select Guide Rating

• UNIT I: Introduction to Physiology: The Cell and General Physiology 1. Functional Organization of the Human Body and Control of the "Internal Environment" 2. The Cell and Its Functions 3. Genetic Control of Protein Synthesis, Cell Function, and Cell Reproduction UNIT II: Membrane Physiology, Nerve, and Muscle 4. Transport of Substances Through Cell Membranes 5. Membrane Potentials and Action Potentials 6. Contraction of Skeletal Muscle 7. Excitation of Skeletal Muscle: Neuromuscular Transmission and Excitation-Contraction Coupling 8. Excitation and Contraction of Smooth Muscle UNIT III: The Heart 9. Cardiac Muscle; The Heart as a Pump and Function of the Heart Valves 10. Rhythmical Excitation of the Heart 11. Fundamentals of Electrocardiography 12. Electrocardiographic Interpretation of Cardiac Muscle and Coronary Blood Flow Abnormalities: Vectorial Analysis 13. Cardiac Arrhythmias and Their Electrocardiographic Interpretation UNIT IV: The Circulation 14. Overview of the Circulation: Pressure, Flow, and Resistance 15. Vascular Distensibility and Functions of the Arterial and Venous Systems 16. The Microcirculation and Lymphatic System: Capillary Fluid Exchange, Interstitial Fluid, and Lymph Flow 17. Local and Humoral Control of Tissue Blood Flow 18. Nervous Regulation of the Circulation and Rapid Control of Arterial Pressure 19. Role of the Kidneys in Long-Term Control of Arterial Pressure and in Hypertension: The Integrated System for Arterial Pressure Regulation 20. Cardiac Output, Venous Return, and Their Regulation 21. Muscle Blood Flow and Cardiac Output During Exercise; The Coronary Circulation and Ischemic Heart Disease 22. Heart Failure 23. Heart Valves and Heart Sounds; Valvular and Congenital Heart Defects 24. Circulatory Shock and Its Treatment UNIT V: The Body Fluids and Kidneys 25. Regulation of Body Fluid Compartments: Extracellular and Intracellular Fluids; Edema 26. The Urinary System: Functional Anatomy and Urine Formation By the Kidneys 27. Glomerular Filtration, Renal Blood Flow, and Their Control 28. Renal Tubular Reabsorption and Secretion 29. Urine Concentration and Dilution; Regulation of Extracellular Fluid Osmolarity and Sodium Concentration 30. Renal Regulation of Potassium, Calcium, Phosphate, and Magnesium; Integration of Renal Mechanisms for Control of Blood Volume and Extracellular Fluid Volume 31. Acid-Base Regulation 32. Diuretics and Kidney Diseases UNIT VI: Blood Cells, Immunity, and Blood Coagulation 33. Red Blood Cells, Anemia, and Polycythemia 34. Resistance of the Body to Infection: I. Leukocytes, Granulocytes, the Monocyte-Macrophage System, and Inflammation 35. Resistance of the Body to Infection: II. Immunity and Allergy 36. Blood Types, Transfusion, and Tissue and Organ Transplantation 37. Hemostasis and Blood Coagulation UNIT VII: Respiration 38. Pulmonary Ventilation 39. Pulmonary Circulation, Pulmonary Edema, and Pleural Fluid 40. Principles of Gas Exchange; Diffusion of Oxygen and Carbon Dioxide Through Respiratory Membranes 41. Transport of Oxygen and Carbon Dioxide in Blood and Tissue Fluids 42. Regulation of Respiration 43. Respiratory Insufficiency-Pathophysiology, Diagnosis, Oxygen Therapy UNIT VIII: Aviation, Space, and Deep-Sea Diving Physiology 44. Aviation, High Altitude, and Space Physiology 45. Physiology of Deep-Sea Diving and Other Hyperbaric Conditions UNIT IX: The Nervous System: A. General Principles and Sensory Physiology 46. Organization of the Nervous System, Basic Functions of Synapses and Neurotransmitters 47. Sensory Receptors and Neuronal Circuits for Processing Information 48. Somatic Sensations: I. General Organization, Tactile and Position Senses 49. Somatic Sensations: II. Pain, Headache, and Thermal Sensations UNIT X: The Nervous System: B. The Special Senses 50. The Eye: I. Optics of Vision 51. The Eye: II. Receptor and Neural Function of the Retina 52. The Eye: III. Central Neurophysiology of Vision 53. The Sense of Hearing 54. The Chemical Senses-Taste and Smell UNIT XI: The Nervous System: C. Motor and Integrative Neurophysiology 55. Spinal Cord Motor Functions; The Cord Reflexes 56. Cortical and Brain Stem Control of Motor Function 57. Cerebellum and Basal Ganglia Contributions to Overall Motor Control 58. Cerebral Cortex, Intellectual Functions of the Brain, Learning, and Memory 59. The Limbic System and the Hypothalamus-Behavioral and Motivational Mechanisms of the Brain 60. States of Brain Activity-Sleep, Brain Waves, Epilepsy, Psychoses, and Dementia 61. The Autonomic Nervous System and the Adrenal Medulla 62. Cerebral Blood Flow, Cerebrospinal Fluid, and Brain Metabolism UNIT XII: Gastrointestinal Physiology 63. General Principles of Gastrointestinal Function-Motility, Nervous and Hormonal Control, Blood Circulation, and Microbiota 64. Propulsion and Mixing of Food in the Alimentary Tract 65. Secretory Functions of the Alimentary Tract 66. Digestion and Absorption in the Gastrointestinal Tract 67. Physiology of Gastrointestinal Disorders UNIT XIII: Metabolism and Temperature Regulation 68. Metabolism of Carbohydrates and Formation of Adenosine Triphosphate 69. Lipid Metabolism 70. Protein Metabolism 71. The Liver 72. Dietary Balances; Regulation of Feeding; Obesity and Starvation; Vitamins and Minerals 73. Energetics and Metabolic Rate 74. Body Temperature Regulation and Fever UNIT XIV: Endocrinology and Reproduction 75. Introduction to Endocrinology 76. Pituitary Hormones and Their Control By the Hypothalamus 77. Thyroid Metabolic Hormones 78. Adrenocortical Hormones 79. Insulin, Glucagon, and Diabetes Mellitus 80. Parathyroid Hormone, Calcitonin, Calcium and Phosphate Metabolism, Vitamin D, Bone, and Teeth 81. Reproductive and Hormonal Functions of the Male (and Function of the Pineal Gland) 82. Female Physiology Before Pregnancy and Female Hormones 83. Pregnancy and Lactation 84. Fetal and Neonatal Physiology UNIT XV: Sports Physiology 85. Sports Physiology