Cancer Epigenetics and Nanomedicine

Targeting the Right Player via Nanotechnology

Häftad, Engelska, 2024

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Beskrivning

Cancer Epigenetics and Nanomedicine: Targeting the Right Player via Nanotechnology is a complete package that provides a comprehensive and thorough understanding of the key players that modulate the various steps of carcinogenesis and malignant progression of the disease and the critical targets to be exploited for developing novel modalities of diagnosis and therapeutics.

Since epigenetic aberrations can be potentially reversed and restored to their normal state through epigenetic therapy, the book also discusses the challenges and the future of the field with the cutting-edge revelations and limitations that this research endeavor can offer, thereby helping the readers to enhance their critical thinking and adopt strategies of therapeutic importance.

Delivers a detailed and complete journey of how cancer develops, its genetics, as well as other internal and external factors that are contributors of carcinogenesis
Provides in-depth knowledge on epigenetics and the various epigenetic biomolecules, enzymes, and other signaling pathways that are promising entities for drug discovery and chemotherapeutics
Presents state-of-the-art information on the next-generation cancer therapies, challenges, and future of the field

Produktinformation

Utgivningsdatum:2024-07-02
Mått:191 x 235 x 26 mm
Vikt:950 g
Format:Häftad
Språk:Engelska
Antal sidor:458
Förlag:Elsevier Science
ISBN:9780443132094

Utforska kategorier

Hälsoinformatik inom Medicin
Onkologi inom Medicin
Teknik: allmänt inom Naturvetenskap och teknik

Mer om författaren

Dr. Prashant Kesharwani is assistant professor of Pharmaceutics at Department of Pharmaceutical Sciences, Dr. Harisingh Gour Vishwavidyalaya University, Sagar, Madhya Pradesh, India. He has more than 12 years of teaching, research, and industrial experience across various countries. An overarching goal of his current research is the development of nanoengineered drug delivery systems for various diseases. He has published many articles in well-reputed journals and a large number of books. He is a recipient of many research grants from various funding bodies. He is also the recipient of several internationally acclaimed awards, such as “USERN Laureate award, and “SERB-Ramanujan Fellowship Award. He has presented many invited talks and oral presentations at prestigious scientific peer-conferences, received international acclaims and awards for research contribution, supervised students/junior researchers and actively participated in outreach and scientific dissemination for the service of the wider community. Dr. Chitra Thakur is an Assistant Professor-Research in the Department of Pathology at the Stony Brook Cancer Center, New York, USA. She is a cancer biologist and has expertise in molecular oncology, mouse models of human cancers, analyzing big data in translational research, toxicology, and epigenetics in human cancers. She is the recipient of several internationally acclaimed awards such as the “DFG German Excellence Initiative Award,, “NIH-Big Data Training for Translational Omics Research and “American Cancer Society IRG. With more than 45 research articles published in mainstream scientific journals, she has contributed significantly towards the understanding of the molecular mechanisms in human cancers. She is engrossed in cancer research, teaching, and community outreach initiatives, hence fostering the scientific community and health care professionals engaged in cancer diagnosis, and treatment.

Innehållsförteckning

SECTION 1 Overview of cancer, internal and external factors associated with cancer1. Overview of cancer: Mechanisms of carcinogenesis2. Tumor metabolism and micronutrients: New insights to target malignant tumors3. The role of one-carbon amino acids in tumor-immune metabolism: From oncogenesis to therapy4. Environmental causes of cancer5. Cancer stem cells—Challenges for cancer therapies6. Carving a therapeutic niche for metastatic cancer: Opportunities and challengesSECTION 2 Epigenetics and its importance in cancer therapies7. An overview of epigenetics and cancer8. Metabolic adaptation and epigenetic modulations: Unraveling tumor plasticity under variable tumor microenvironment9. Involvement of epigenetic modifications in cancer stem cells and chemoresistance10. Cancer biomarkers: Where genetics meets epigenetics11. Epigenetics approach in cancer treatment with focus on lung and breast cancer12. Dietary components as epigenetic modifiers and their roles in cancer preventionSECTION 3 Nanomedicine targeting epigenetic machinery in cancer therapy13. Harnessing plant-derived biosynthetic nanomaterials for epigenetic modulation in cancer therapy14. Nanotechnology-enhanced immunotherapy for cancer15. Nanoparticles in metastatic cancer treatment16. Amine-terminated dendrimers: A novel method for diagnose, control and treatment of cancer17. Nanomedicine and epigenome: Possible health risks, benefits, and future perspectives18. Smart cancer nanomedicine: Challenges and future opportunities