Caspases as Molecular Targets for Cancer Therapy

Dr. Ankur Vaidya obtained his PhD from Dr. H.S. Gour University, when he researched design, synthesis, and screening of a few quinoline and oxadiazole derivatives for anticancer activities. He has 12 years of experience in teaching and research, and already supervised 18 PhD students. He wrote 5 book chapters and co-authored 2 books, including Nanotechnology Applications for Cancer Chemotherapy (Elsevier, 2020).

• 1. Introduction to caspases, its function, mechanism, and classificationSushanta Bhattacharya, Shankar Gupta and Vivek Asati2. Mutations within apoptosis gene and caspasesManya Khurana, Paranjeet Kaur, Somdutt Mujwar, Manjinder Singh and Sanjeev Kumar Sahu3. Inflammatory caspase-1, -4, and -5 and their role in anticancer activityRuchi Shakya, Navneesh, Shivanshu Pandey, Sumit Pasricha, Balak Das Kurmi and Preeti Patel4. Caspase-2 and tumor suppressionRavindra Kumar Chourasiya, Ankur Vaidya and Alok Nahata5. Caspase-3: A promising target for anticancer agentsSushmita Pandey, Shweta Jain, Sanjeev Sahu, Vinod Gurjar and Ankur Vaidya6. Caspase 7 mutations and their activatorsSanjeev Kumar Sahu, Charanjit Kaur, Ankit Yadav, Yashraj Potale, Paranjeet Kaur, Shweta Jain and Ankur Vaidya7. Reinstating the expression and activation of caspase-8 and caspase-10 in cancer therapyVinod Kumar Gurjar, Shweta Jain, Ankur Vaidya and Kuldeep Bansal8. Caspase-9 gene mutation and its activatorsRavichandran Veerasamy9. Caspases activity assay proceduresSourabh Satapathy, Shivam Kumar, Vaibhav Nigam, Balak Das Kurmi, Ankur Vaidya, Akash Ved and Preeti Patel10. Current and future prospective of caspases targeting in cancer therapyDisha Prabhu, Surendra Jain, Rakesh Chawala, Shweta Jain and Ankur Vaidya