Organic Synthesis

Professor Michael B. Smith received an A.A. from Ferrum College in 1967 and a BS in chemistry from Virginia Polytechnic Institute in 1969. After working for 3 years at the Newport News Shipbuilding and Dry Dock Co. in New- port News VA as an analytical chemist, he entered graduate school at Purdue University. He received a PhD in Organic Chemistry in 1977. He spent 1 year as a faculty research associate at the Arizona State University with Professor G. Robert Pettit, working on the isolation of cytotoxic principles from plants and sponges. He spent a second year of postdoctoral work with Professor Sidney M. Hecht at the Massachusetts Insti- tute of Technology, working on the synthesis of bleomycin A2.  Smith began his academic career at the University of Connecticut in 1979, where he is currently professor of chemistry. In addition to this research, he is the author of the fifth, sixth, and seventh editions of March’s Advanced Organic Chemistry. He is also the author of an undergraduate textbook in organic chemistry titled Organic Chemistry. An Acid-Base Approach, now in its second edition. He is the editor of the Compendium of Organic Synthetic Methods, Volumes 6–13. He is the author of Organic Chemistry: Two Semesters, in its second edition, which is an outline of undergraduate organic chemistry to be used as a study guide for the first organic course. He has authored a research monograph titled Synthesis of Non-alpha Amino Acids, in its second edition.

• 1. Retrosynthesis, Stereochemistry, And Conformations2. Acids And Bases and Addition Reactions3. Functional Group Exchange Reactions4. Acids, Bases, And Functional Group Exchange Reactions5. Functional Groups Exchange Reactions6. Functional Group Exchange Reactions. Oxidations7. Functional Group Exchange Reactions. Reductions8. Synthetic strategies9. Functional Group Exchange Reactions.  Hydroboration10. Functional Group Exchange Reactions11. Carbon-Carbon Bond-Forming Reactions.   Cyanide, Alkyne Anions, Grignard Reagents, and Organolithium Reagents12. Carbon–Carbon Bond-Forming Reactions.   Stabilized Carbanions, Organocuprates, and Ylids13. Carbon-Carbon Bond-Forming Reactions.   Enolate Anion14. Pericyclic Reactions.  The Diels–Alder Reaction15. Pericyclic Reactions: [m+n]-Cycloadditions, Sigmatropic Rearrangements,   Electrocyclic and Ene Reactions16. Carbon-Carbon Bond-Forming Reactions.   Carbocation and Oxocarbenium Ion Intermediates17. Formation Of Carbon-Carbon Bonds Via Radicals and Carbenes18. Metal-Mediated, Carbon-Carbon Bond-Forming Reactions19. Combinatorial And Process Chemistry