Cardiopulmonary Bypass

After finishing the Medicine Faculty of Istanbul University in 1990, Prof Kırali fulfilled MD, MSc medical mandatory service duty and began his residency training in Koşuyolu Heart and Research Hospital in 1992. Following 5 years of assistant education, he was in England and the USA for education and training in 1998. He performed his work mostly in the field of videoscopic and minimally invasive cardiac surgery, and he became a consultant cardiovascular surgeon in 1998, Assistance Professor in 1999, Associate Professor in 2002, and chief in 2005 at the same hospital. Over the last 20 years, he has focused his scientific interests on topics related to cardiovascular repairs requiring special experience. With his expertise in coronary artery surgery, minimal invasive cardiac surgery, valve repair, and aortic root surgery, he has established new methods for awake coronary bypass revascularization, new surgical approach for AVR during first and re-operations, aortic valve sparing procedure, and radiofrequency ablation. He is the pioneer of awake complete CABG with BIMA and has also developed a new aortotomy incision technique for all kinds of aortic valvular or subvalvular interventions during first and re-operations, which simplifies the procedure with/without aortic valve insertion. He has experience on cardiac failure during ECMO and developed a specific design for recovery. He has been the director of transplantation department since 2015. Prof. Joseph Coselli is the chief Professor of Surgery, of the Division of Cardiothoracic Surgery and the Executive vice-chair of Michael E. DeBakey Department of Surgery at Baylor College of Medicine, United States. He has specialized in the evaluation and treatment of aortic disease, including the aortic valve and root, the aortic arch, and the thoracoabdominal aorta, using open surgical and endovascular techniques. In 40 years of service, he has performed more than 10,500 aortic repairs, including more than 3700 repairs of thoracoabdominal aortic aneurysms, for which he is world-renowned. Prof Kalangos MD, PhD is a Greek-Swiss cardiovascular surgeon and Philanthropist. He currently serves as the Chairman of the Department of Pediatric and Congenital Cardiovascular Surgery at Mitera Hospital in Athens and as a full Professor of Pediatric Cardiovascular Surgery at Koc University Hospital in Istanbul, Türkiye. He is the President and founder of the Kalangos Foundation, the President and founder of the Global Forum on Humanitarian Medicine in Cardiology and Cardiac Surgery and the President and co- founder of Global Heart Network. He was the former President of the World Society of Cardiovascular and Thoracic Surgeons in 2014-2015 and is currently the treasurer of the society. He is also the inventor of the Kalangos biodegradable annuloplasty Rin. This device is being used in the repair of the mitral and tricuspid valves especially in children.

• VOLUME IPART I. Extracorporeal Life SupportEditorialKaan KıraliIntroduction: Surgical PerspectiveMarko TurinaIntroduction: Perfusional PerspectiveGerard J. MyersPART II. Artificial Circulation and Respiration1. Development of Extracorporeal CirculationSteven Tsui and Ismail Vokshi2. Future Artificial Surface PhysiologyManoj Myneni and Keshava Rajagopal3. Future Artificial HeartO.H. Frazier4. Future Artificial LungJustyna Swol5. Future Noninvasive MonitoringSilvia Mariani, Maria De Piero and Axel Haveric6. 3D Printing for Artificial PhysiologyZhonghua Sun7. Advances for Artificial Circulation GuidelinesKaan KıraliPART III. Cardiopulmonary Bypass (CPB)8. Basics of Extracorporeal CirculationVipin Zamvar and Peter Lang9. Pathophysiology of Cardiopulmonary BypassKaan Kırali, Davut Çekmecelioğlu, Tanıl Özer, Tolga Baş and Hülya Yük10. Microcirculation During Cardiopulmonary BypassThanos Athanasiou, Maria Fergadi and Dimitrios Magouliotis11. Standards for Cardiopulmonary BypassDavid Fitzgerald and Justin Resley12. Mechanical Pumps for Cardiopulmonary BypassGeorg Maximilian Wieselthaler13. Oxygenators for Cardiopulmonary BypassKorneel Vandewiele and Stefaan Bouchez14. Cannulations for Cardiopulmonary BypassGino Gerosa, Assunta Fabozzo and Chiara Tessari15. Anesthesia During Cardiopulmonary BypassAntonio Pisano, Carolina Soledad Romero García, Nicola Galdieri and Giovanni Landoni16. Monitoring During Cardiopulmonary BypassKaan Kırali, Mustafa EMRE Gürcü, Pınar Karaca Baysal and Özlem Oğuzhan17. Transesophageal Echocardiography During Cardiopulmonary BypassFederico Pappalardo, Giulia Maj and Stephanie Bertolin18. Hemostasis During Cardiopulmonary BypassGiuseppe G. Faggian, Francesco Onorati, Ilaria Tropea, Annalisa Bernabei and Alessandra Francica19. Myocardial Preservation During Cardiopulmonary BypassKaan Kırali, Hakan Hançer, Taylan Adademir, Tolga Baş and Mine Şimşek20. Cerebral Preservation During DHCA in Cardiopulmonary BypassShahzad G. RajaPART IV. Special Cardiopulmonary Bypass21. Cardiopulmonary Bypass in PregnancyHartzell Schaff and Sri Harsha Patlolla22. Cardiopulmonary Bypass in Neonates and InfantsAkif Undar, Ryan M. Holcomb, Krishna Patel and Yongwook Dan23. Cardiopulmonary Bypass in PediatricsAfksendiyos Kalangos and Nataliia Shatelen24. Cardiopulmonary Bypass in Thoracic Aortic SurgeryDavut Çekmecelioğlu, Kathleen Kibler, Vicente Orozco-Sevilla, and Joseph S. Coselli 25. Cardiopulmonary Bypass in Lung TransplantationAlexander Sasha Krupnick, Aakash Shah and Joshua L. Leibowitz26. Cardiopulmonary Bypass in Non-Cardiac Thoracic SurgeryBaşar Sareyyüpoğlu, Magdy M. El-Sayed Ahmed and Mathew ThomasPART V. Special Situations for Perfusion 27. Perfusion Ethics, Accreditation and EducationDavid Fitzgerald and David Fisher Jr28. Perfusion TrainingSven Maier and Christoph Benk29. Perfusion ManagementFilip De Somer30. Perfusion Accidents ManagementCarrel Thierry, Erich Gygax and Sarah Longnus-Henning31. Perfusion Separation ChallengeVladimir Lomivorotov and Ludmila Lomivorotova32. Perfusion for HIPECMustafa Duman, Erdal Polat, Mehmet Can, Kaan Kırali and Ercan ErsoyPart VI. Miniaturizing Cardiopulmonary Bypass 33. Miniaturizing Cardiopulmonary Bypass (MiCPB)Kyriakos Anastasiadis, Polychronis Antonitsis, Kyriakos Anastasiadis, Helena Argiriadou and Apostolos Deliopoulos34. MiCPB in Cardiac SurgeryKonstantinos S. Mylonas and Dimitrios V. Avgerinos 35. MiCPB in Heart Valve SurgeryKaan Kırali36. MiCPB in Robotic Cardiac SurgeryMichael J. Bates, W. Douglas Boyd, L. Wiley Nifong and Randolph Chitwood37. MiCPB in PediatricsGiovanni Battista Luciani, Alessio Rungatscher, Daniele Linardi and Stiljan HoxhaPart VII. Organ Injury and Protection in Cardiopulmonary Bypass 38. Metabolic Aspects in Cardiopulmonary BypassJohn R. Cooper Jr, Katherine Gordon and Claudia Yu Yao Wei39. Inflammatory Injury in Cardiopulmonary BypassShahzad G. Raja40. Inflammatory Protection and Immune Support for Cardiopulmonary BypassShahzad G. Raja41. Lung Injury in Cardiopulmonary BypassStephen C. Clark and Vikrant Pathania42. Pulmonary Protection and Respiratory Support for Cardiopulmonary BypassKaan Kırali, Halide Oğuş, Mustafa Mert Özgür and Uğur Eke43. Brain Injury in Cardiopulmonary BypassMichael P. Vallely, Fabio Ramponi, Kaye Hon, Michael Seco, John D. Puskas, Jonathon Fanning, Stuart Grieve, Paul Bannon and Leonard Kritharides44. Cerebral Protection and Neurologic SupportJohn M. Murkin and Agya Boakye Atonsah Prempeh45. Kidney Injury in Cardiopulmonary BypassEduard Quintana, Cristina Ibáñez, Juan Perdomo, Alícia Molina-Andujar and Esteban Poch46. Renal Protection and Nephritic Support for Cardiopulmonary BypassKaan Kırali, Özge Altaş, Mustafa Emre Gürcü and Şefika Kılıç47. Splanchnic Protection and Support for Cardiopulmonary BypassPaulo Roberto Barbosa Evora, Gabriel Bianco Giuliani, Cecilio Jacob and Patricia Martinez48. Intestinal Protection and Enteric Support for Cardiopulmonary BypassAmer Harky, Kelly Wright and Naomi Melamed49. Endocrinological Protection and Hormonal Support for Cardiopulmonary BypassPaulo Roberto Barbosa Evora, Gabriel Bianco Giuliani, Cecilio Jacob and Patricia Martinez50. Vessels Injury in Cardiopulmonary BypassAssunta Fabozzo, Chiara Tessari, Giorgia Cibin and Gino Gerosa51. Infectional Protection and Antimicrobial Support for Cardiopulmonary BypassKaan Kırali, Yeşim Uygun Kızmaz, Pınar Atagün Güney and Nuray ÇankayaVOLUME IIPart VIII. Extra Corporeal Membranous Oxygenation (ECMO)52. Extracorporeal Membrane Oxygenation (ECMO)Kaan Kırali, Atakan Erkılınç, Serpil Gezer Taş and İsmail Yerli53. Contraindications for ECMOJohn Kyle Bohman, Misty Radosevich and Shihab Sugeir54. Hemodynamic Evaluation of Cannulas for ECMOAkif Undar, Krishna Patel, David Palanzo, Christoph Brehm and John L. Myers55. ECG-Synchronized Pulsatility for ECMOAkif Undar, Estelle Green, Orhun Davarci, Krishna Patel and Joseph B. Clark56. Cardiac Protection and Management during ECMOKaan Kırali, Deniz Günay, Mehmet Aksüt, Sabit Sarıkaya and Hacı Aslan57. Pulmonary Protection and Management during ECMOSteven Keller58. Hemorraghic Protection and Management during ECMOHanne Berg Ravn and Henrik Schmidt59. Cerebral Protection and Management during ECMOMirko Belliato, Andrea Pellegrini and Roberto Veronesi Sr.60. Renal Protection and Management during ECMOKaan Kırali, Murat Gücün, Aytaç Polat and Nazlı Kılıç61. Gastrointestinal Protection and Management during ECMOPaulo Roberto Barbosa Evora, Cecilio Jacob, Gabriel Bianco Giuliani and Patricia Martinez62. Vascular Protection and Management during ECMOSubhasis Chatterjee, Chibueze Onyemkpa, Zachary Pallister, Orlando Suero and Jayer Chung63. Infection Protection and Management during ECMONicolo Patroniti and Angelo Insorsi64. Inflammatory Protection and Management during ECMOKiran Shekar, Elliott Theodrose Worku and Katrina K. KiPart IX. Special Situations for ECMO 65. Ethics and Quality Assurance for ECMOKollengode Ramanathan, Kiran Shekar and Ujwal Dhundi66. Education and Training for ECMOMelissa Brunsvold, Robert E Bulander Jr and Ahmad Abutaka67. Nursing Care for ECMOJo-anne Fowles and Andrew Hadley-Brown68. Transport and Retrieval for ECMOAhmed Labib and Guillaume Alinier69. Weaning Strategies for ECMO and Awake ECMOWiebke Sommer and Gregor Warnecke Part X. ECMO Support in Non-Cardiac Etiology 70. ECMO in Neonates and InfantsDenise Suttner71. CRRT during ECMO in Neonates and InfantsAkif Undar, Lilly Su, Ryan M. Holcomb and John L. Myers72. ECMO in Nonsurgical Lung ConditionsJohn Kyle Bohman, Juan Camilo Diaz Soto and Misty Radosevich73. ECMO in Lung SurgeryShahrokh Taghavi, Alberto Benazzo, Konrad Hötzenecker and Anders Andreasson74. ECMO in Intracranial SurgeryGevalin Srisooksai and Christoph N. Seubert75. ECC/ECMO in Controlled Reperfusion of Whole Body (CARL)Georg Trummer, Christoph Benk, Jan-Steffen Pooth, Sam Brixius and Friedhelm Beyersdorf76. ECMO in Accidental HypothermiaKiran Shekar, Saikat Mitra, Kollengode Ramanathan and Justyna Swol77. ECMO in TraumaAkbarshakh Akhmerov and Danny Ramzy 78. ECMO in PandemicsCara Agerstrand, Briana Short, Philippe H. Lemaitre and Meaghan Flatley79. ECMO in COVID-ARDSKaan Kırali, Adile Ece Altınay, Şirin Menekşe and Sibel AydınPart XI. ECMO Support in Non-Surgical Cardiac Etiology 80. ECMO for Challenging Percutaneous InterventionMatthew Acton, Corbin E. Goerlich and Ahmet Kilic,81. ECMO for End-stage Heart FailureAhmet Kilic, Corbin E. Goerlich and Matthew Acton82. ECMO for Cardiogenic ShockIbrahim Akin, Michael Behnes and Tobias Schupp83. ECMO for Cardiopulmonary Arrest (E-CPR)Hanne Berg Ravn and Henrik SchmidtPart XII. ECMO Support in Surgical Cardiac Etiology 84. ECMO for Postcardiotomy Syndrome in AdultsAlexis Edward Shafii and Bhalinder Dhaliwal85. ECMO for Postcardiotomy Syndrome in PediatricsKatsuhide Maeda and Tracey R. Geoffrion86. ECMO for post-LVAD Right Ventricular FailureJasmin Sarah Hanke, Güneş Doğan and Jan D. Schmitto87. ECMO for Thoracic TransplantationLeslie James, Deane E. Smith and Nader MoazamiPart XIII. Non-ECMO Artificial Life Support 88. Non-ECMO Artificial Circulatory Support DevicesMevlut Çelik and Simon Maltais89. Non-ECMO Artificial Respiratory Support DevicesJung-Yien Chien, Ting-Yu Liao and Yih-Sharng Chen 90. Non-ECMO Artificial Circulatory Support for Postcardiotomy SyndromeKenneth K. Liao and Harveen Lamba91. Non-ECMO Artificial Circulatory Support for Percutaneous InterventionsGregory W. Serrao, Anoop Ninan Koshy and Samin Sharma92. Non-ECMO Artificial Life Support for Thoracic TransplantationJae-Seung Jung and SeokJin HaamEpilogueKaan Kırali