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    1. Naturvetenskap och teknik
    2. Matematik och naturvetenskap
    3. Fysik
    4. Tillämpad fysik

    Lipid Analysis in Biology, Health, and Disease

    AvSanjoy K. Bhattacharya

    Häftad, Engelska, 2025

    1 776 kr

    Beställningsvara. Skickas inom 10-15 vardagar. Fri frakt över 249 kr.

    Beskrivning

    Lipid Analysis in Biology, Health, and Disease bridges the gap between discovery science and clinical lipidology, empowering both scientific and medical communities to apply lipid analysis and understanding in new research, as well as diagnosis and management of diseases. Here, international experts in the field begin with the basic biology of the lipids, followed by methods and technology for study, and lipids in lab medicine and epidemiology. This book uniquely combines biology and analysis to drive healthcare advances, with a diverse range of technologies and analytic methods considered.

    Basic lipid biology chapters discuss membrane expansion, lysosomal positioning, mitochondrial biogenesis, lipid-protein interactions, molecular dynamics, cholesterol transport, immune activation and inflammation, lipid droplets, and gender differences in lipid metabolism. Each disease chapter incorporates basic lipid epidemiology, risk factors, and genetic associations.



    • Covers diverse technologies for lipid research and analysis, as well as clinical applications from membrane simulation to drug delivery systems
    • Includes applied, translational case studies, and research examples throughout
    • Features chapter contributions from international experts in the field

    Produktinformation

    • Utgivningsdatum:2025-09-23
    • Mått:216 x 276 x 28 mm
    • Vikt:1 760 g
    • Format:Häftad
    • Språk:Engelska
    • Antal sidor:648
    • Förlag:Elsevier Science
    • ISBN:9780443191169

    Utforska kategorier

    • Tillämpad fysik inom Naturvetenskap och teknik
    • Biokemi inom Naturvetenskap och teknik

    Mer om författaren

    Sanjoy Bhattacharya is a tenured full Professor at the Department of Ophthalmology, University of Miami, with secondary appointments in biochemistry, molecular biology, neuroscience, cellular and molecular pharmacology programs. He earned his doctorate in Biochemical Engineering and Biotechnology. Dr. Bhattacharya’s laboratory, with its diverse expertise in engineering, computer programming, biology, and mass spectrometry, is dedicated to studying the complete set of molecules and biological systems involved in axon regeneration. He serves on the editorial board of several peer-reviewed journals including PLoS One as an academic editor, Experimental Eye Research as Special issues and Review editor, and Translational Metabolomics as the Editor in Chief. Professor Bhattacharya has held several leadership positions including Chair of the scientific advisory board of Malignancy Research Foundation and Chair of Miller School of Medicine Faculty Council. He is also the founding director of Miami Integrative Metabolomics Research Center.

    Innehållsförteckning

    • Section 1: Lipids in Different Aspects of Biology:1. Membrane Expansion2. Contribution of lipids towards membrane curvature3. Lipid-Protein Interactions and Molecular Dynamics Simulation4. Lipid Droplets in Biology5. Lysosome and lipid metabolism6. Mitochondrial and Cardiolipin Biology7. Cholesterol transport by various lipoproteins8. Lipids mediators in viral infection and immunity9. Gender Differences in Lipid MetabolismSection 2: Analytical Technologies10. Analyses of different aspects of lipids: General methods11. Current LC-MS/MS methods in lipidomics12. Gas chromatography-mass spectrometry (GC-MS) analyses of lipids13. Rapid and unbiased screening of serum lipid ratios using AP MALDI-HRMS14. Nuclear magnetic resonance (NMR) methods for Lipid analysis15. The statistical analysis of ‘Omics datasets: challenges, pitfalls, and tips16. Differences in lipidomic analysis using different bioinformatics software17. Metabolomics Tools for the Analysis of Phospholipids as Potential Markers to Decipher the Molecular Mechanisms Behind Diseases18. Lipid Imaging: Microscopy-Based Techniques for Lipid Membrane CharacterizationSection 3: Lipids in Lab and Investigational Medicine19. Multi-omics biomarkers of health and disease20. The Multifactorial Pathobiology of Lipidic Quorum Signaling Molecules of Pseudomonas aeruginosa21. Targeting Fatty Acid Transport in Dietary Lipid Absorption: A Therapeutic Approach for Metabolic Disorders.22. Lipoprotein metabolism and female fertility23. The Role of Maternal Omega-3 Supplementation in Shaping Offspring Skeletal Health24. Oxidized lipids and age-related macular degeneration25. Lipidomics of Human Aqueous Humor26. Drug Delivery Systems Involving LipidsSection 4: Lipids in Clinical Medicine27. Cardiovascular diseases and cholesterol28. Cholesterol and Spingolipids in Alzheimer's disease29. Cardiac lipotoxicity in diabetes and obesity30. Lipid metabolism in type 1 diabetes initiation and progression to vascular disease31. Role of the Gut Microbiome in Lipid Metabolism and type 1 diabetes32. Elevated LDL levels and lung cancer33. Pathophysiology and Clinical Medicine of Dyslipidemia after Spinal Cord Injury34. Targeting transcription control of lipid biogenesis to tune intraocular pressure35. Inflammatory Bowel Disease36. Atherosclerosis and Inflammation37. Lipidomics in Skeletal Muscle: Unveiling the Roles of Lipid Mediators in Muscle Biology38. Lipidomics in Skeletal Muscle: Unveiling the Roles of Lipid Mediators in Muscle Pathophysiology39. Lipidomics in Bone: Unveiling the Roles of Lipid Mediators in Bone Biology and Pathophysiology40. Associations of Lipids With Diseases in Large Cohort Studies and Randomized Trials