Gabriella Bettelli is past-Director of the Geriatric Surgical Area and Anesthesia Unit at the INRCA (Italian National Research Centre on Aging, Ancona Italy), specialist in anesthesia, cardiology, and geriatrics (2nd Level University Master). She founded and currently coordinates an international 2nd Level University Master in Perioperative Geriatric Medicine, held in co-partnership by the San Marino University and the Catholic University of Rome. She edited the book Perioperative Care of the Elderly: clinical and organizational aspects (Cambridge University Press, 2017), co-edited various books on safety in anesthesia, and published more than 120 papers, most of them indexed. She is a member of the ESAIC Task Force for Postoperative Delirium GL, currently under updating, and reviewer for Anesthesia & Analgesia, Journal of Gerontology, Journal of Frailty and Aging and Saudi Journal of Anesthesia. Riccardo A. Audisio, MD, PhD (Hon), FRCS, is past-President of SIOG (International Society of Geriatric Oncology), BASO (British Association of Surgical Oncology) and ESSO (European Society of Surgical Oncology). He served as an advisor to the Department of Health, UK and to the All-Party Parliamentary Group on Breast Cancer in Older Women. Professor Audisio sat on the Board of Directors of ECCO (European Cancer Organization). He is past-Chair of the Education & Training Committee of ESSO. Professor Audisio chairs the Surgical Oncology track at the Global Health Catalyst, Harvard Medical School. He has edited 10 books on the management of Elderly Cancer Patients (Springer), co-edited the ESMO Handbook of Cancer in the Senior Patient, and authored over 30 peer reviewed papers on the topic. His clinical research focuses on Breast Cancer, Geriatric Oncology, Education/Certification in Surgical Oncology and the optimization of Surgical Oncology in L/MICs.

• Part I. Pre-Operative Management1. Epidemiological and structural overview of the current situation2. Aging, pathophysiological changes and their impact on anesthesia and surgery3. Preoperative evaluation and optimization: a team-based task4. Decision making about surgery and plan for hospital admission5. Patient allocation and preparation to surgeryPart II. Peri- and Post-Operative Management 6. Anesthesia techniques, intraoperative management, and early postoperative recovery7. Team-based approach to surgical stress reduction and procedural safety8. General principles for optimal postoperative recovery9. Postoperative ICU care10. Post-operative course at the ward11. The clinical path: hospital discharge. Management of hospital discharge and late postoperative recoveryPart III. Surgical Issues 12. Surgery for older patients: An overview13. The impact of ERAS and fast-track surgery in senior patients14. Breast surgery in older women15. Thoracic Surgery in elderly patients16. Emergency general surgery in older patients17. Supporting Older Adults Safely through Abdominal Surgery: The Impact of Prehabilitation and Geriatric-Co Management18. Orthopedic Surgery and Hip Fractures in Elderly Patients19. Gallbladder surgery at an advanced age20. Cataract surgery in the elderly21. Presbystasis and vestibular rehabilitation in elderly patients22. Head and Neck Surgery for Older Patients23. Diverticular disease in older patients24. Patient Frailty and plastic surgery at an advanced age25. Outpatient surgery: day surgery and office-based surgery for senior patients26. Unveiling the Dynamics of Functional Recovery and Quality of Life in Geriatric Patients with CancerPart IV. Recommendations for a Better Future27. Models of care: Purposes, internal organization and inspiring principles28. Towards a “Silver Architecture”: Hospital Design for Geriatric Surgery29. Towards a “Silver Architecture”: Patient safety and clinical risk management30. Ethical principles: professional duties and patients’ rights31. Cornerstones for Optimal Surgical Care of the Older Adult – Current State and Moving the Needle Forward