The Cardiovascular System

From Bench to Bedside

AvHussein Hassan Sabit

Häftad, Engelska, 2025

Del i serien Stem Cell Innovation in Health & Disease

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Beskrivning

The series "Stem Cell Innovation in Health & Disease" is a timely and fascinating collection of information and new discoveries and provides a contemporary snapshot album from the fast-moving field of regenerative medicine and stem cell therapeutics. The Cardiovascular System, Volume 6 addresses the recent data accumulated on the potential applications of stem cells to treat diseases and disorders of the cardiovascular system. This volume will highlight the recent developments of cutting-edge in vitro and in vivo research tools and approaches, including the human and murine organoid cultures, genetic editing in vitro and in vivo, human iPSC models of diseases, haploid cells for genetic as well as compound screening paradigms, genetically engineered mice, and stem cell transplantation to treat cardiovascular system disorders and diseases. The volume is written for researchers and scientists in stem cell therapy, cell biology, regenerative medicine, and organ transplantation; and is contributed by world-renowned authors in the field.

Provides cutting-edge research to understand stem cell functions used in disease and disordertreatments of the cardiovascular system
Develops processes to bring stem cells from bench to bedside
Includes up to date references on stem cell biology and function in common cardiovascular system diseases and disorders

Produktinformation

Utgivningsdatum:2025-07-23
Mått:152 x 229 x 13 mm
Vikt:330 g
Format:Häftad
Språk:Engelska
Serie:Stem Cell Innovation in Health & Disease
Antal sidor:150
Förlag:Elsevier Science
ISBN:9780443298905

Utforska kategorier

Fysiologi inom Medicin
Hjärt- och kärlsjukdomar inom Medicin

Mer om författaren

Hussein Sabit graduated from Ain Shams University, Cairo and received his BSc in Genetics, where he also get his MSc in Microbial Genetics and PhD in Molecular Genetics. He joined Misr University for Science and Technology, Egypt as TA, Assistant Professor. Has been promoted to Associate Professor of Molecular Genetics, and Full Professor in Cancer Epigenetics. His research interest is Cancer Genetic/Epigenetic basis of carcinogenesis, genome editing via CRISPR/Cas9, studying the anti-apoptotic genes and its relations with BC progression, investigating the DNA methylation levels controlling carcinogenesis of BC, studying the chromatin remodelling as a main mechanisms leading to cancer using ChIP assays and others. He published 28 articles; most of them is the main field of Cancer Genetics/Epigenetics. He is the director of Cancer Epigenetics Research Unit (CERU) at MUST, where he leads a research team of postgrad students.

Innehållsförteckning

1. Organoid Culture System as Innovative Model of Heart Stem Cell-Based Cardiac Development and Diseases2. Innovated Therapeutic Gene Editing Technologies in Stem Cell Engineering and Cardiovascular Disorders and Diseases3. Cardiotoxivity and Cancer Therapy: Mechanisms, Implications, and Mitigation Strategies4. Advances in stem cell-based therapy of cardiovascular diseases and disorders5. Derivation and Application of Embryonic Stem Cells as a Model for Heart Development Diseases and Disorders6. The Potential of Mesenchymal Stem Cell Related Therapies for Cardiovascular Diseases and Disorders7. Stem Cell Innovation in Cardiovascular Disease, Repair and Regeneration: General Conclusion, Challenges and Prospective