The Potential of Intermittent Fasting in Age-related Diseases and Precision Anti-aging Therapeutics

AvAbhishek Kumar Singh,Jitendra Kumar Sinha

Häftad, Engelska, 2025

1 666 kr

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Beskrivning

The Potential of Intermittent Fasting in Age-related Diseases and Precision Anti-aging Therapeutics takes an in-depth look at the beneficial and efficacious role of Intermittent Fasting (IF) in a wide array of aging-associated diseases. It provides a comprehensive resource that not only outlines the potential benefits and future research directions but also delves into the limitations and nuances of IF in managing these conditions. The book is divided sections and begins by covering the fundamentals of aging and the effects of IF. Subsequent sections examine the physiological impact IF has on aging; its potential influence on stress resistance, heart, gut, and overall health optimization; social and ethical considerations as a therapeutic strategy; bridging IF research findings and clinical practice; and the potential integration and application of IF into age-related diseases treatment. Offering a consolidated and scientifically grounded perspective aimed at equipping readers with a balanced understanding, this book serves as a go-to reference for researchers and clinicians alike seeking clear and accurate insights into how IF can positively influence the health and longevity of the aging population.

Offers comprehensive coverage of the intricacies of IF and its promising implications in age-related diseases and precision antiaging therapeutics
Explores IF's mechanistic insights and mode of action in disorders associated with aging and lifestyle changes
Discusses cutting-edge advancements in biomedicine and treatment strategies linked to aging-related conditions through IF-focused research

Produktinformation

Utgivningsdatum:2025-11-27
Mått:191 x 235 x undefined mm
Vikt:450 g
Format:Häftad
Språk:Engelska
Antal sidor:460
Förlag:Elsevier Science
ISBN:9780443300608

Utforska kategorier

Geriatrik inom Medicin

Mer om författaren

Dr. Abhishek Kumar Singh is Associate Professor at Manipal Centre for Biotherapeutics Research, Manipal Academy of Higher Education, India. Dr. Singh obtained his PhD from the CSIR-Indian Institute of Toxicology Research, India, and brings more than a decade of research experience in neurodegeneration and neuroprotection. His research focuses on developing anti-aging strategies targeting autophagy pathways in brain aging and age-related neurodegenerative disorders. Dr. Singh has corresponding teaching experience in biomaterials, bioprocess engineering, and gene therapy.Dr. Jitendra Kumar Sinha is a neuroscientist and Associate Professor at the Symbiosis Institute of Health Sciences (SIHS), Symbiosis International (Deemed University), Pune, India. He received his PhD from the ICMR–National Institute of Nutrition and has undertaken internationally collaborative research at institutions in Italy, Australia, and India. With over two decades of experience in research and teaching, his work focuses on the neurobiology of ageing and obesity, nutritional neuroscience, neuropsychiatric disorders, and neuropharmacology. He has made notable contributions to animal models of ageing and epilepsy, particularly in understanding oxidative stress, DNA damage, and biomarkers of accelerated ageing. Dr. Sinha has authored more than 150 research articles and book chapters and actively contributes to the scientific community as an editor and reviewer. He is also deeply engaged in mentoring and academic capacity building.Affiliations and expertiseSymbiosis Institute of Health Sciences (SIHS), Symbiosis International (Deemed University), IndiaDr. Raviraja Seetharam is Professor and Head of Manipal Centre for Biotherapeutics Research, Manipal Academy of Higher Education, India. Dr. Seetharam obtained his MSc and PhD in Biosciences from Mangalore University, India, and completed post-doctoral research at Mount Allison University, Canada, and Albert Einstein College of Medicine, USA. He brings nearly 30 years of research experience in regenerative medicine, microbiology, and cell and molecular biology. He is a lifetime member of the International Society for Stem Cell Research (ISSCR), USA.

Innehållsförteckning

PART I Fundamentals of aging and intermittent fastingCHAPTER 1 Influence of intermittent fasting on age-related diseases and mechanistic understandingCHAPTER 2 Role of intermittent fasting, chronobiology, and circadian rhythms in aging and diseaseCHAPTER 3 Cellular autophagy and aging: role in intermittent fasting-induced health benefitsPART II Physiological impact of intermittent fasting on agingCHAPTER 4 Metabolic health and intermittent fasting: implications for age-related disordersCHAPTER 5 Neurological aging: neuroprotective effects of intermittent fastingCHAPTER 6 Inflammation, immunity, and intermittent fasting: modulating age-related inflammatory processesCHAPTER 7 Epigenetic modifications and aging: intermittent fasting as a catalyst for positive epigenetic changesCHAPTER 8 Mitochondrial health and longevity: intermittent fasting’s impact on cellular energy productionPART III Therapeutic applications of intermittent fasting in agingCHAPTER 9 Hormesis and adaptive responses: intermittent fasting-induced stress resistance and disease resilienceCHAPTER 10 Intermittent fasting and circadian clocks in cardiovascular agingCHAPTER 11 Gut microbiota and aging: intermittent fasting’s influence on gut–brain axis and systemic healthCHAPTER 12 Precision nutrition and personalized intermittent fasting: tailoring therapeutics for optimal agingCHAPTER 13 Translating intermittent fasting research into clinical practice: challenges and opportunitiesPART IV Bridging research and practice in intermittent fasting for agingCHAPTER 14 Future directions in intermittent fasting and aging research: unexplored avenues and collaborative effortsCHAPTER 15 Interplay between diet, exercise, and intermittent fasting in metabolic disease reduction in people with obesity and promoting healthy agingCHAPTER 16 The benefits of diet and exercise on delaying heart and brain aging in obesityCHAPTER 17 Intermittent fasting as complementary therapy in aging-linked diseases