Electrocardiographic Left Ventricular Hypertrophy

Ljuba Bacharová, MD, MBA, DSc, is the senior research leader at the International Laser Center CVTI, and a part-time teacher at both the Slovak Medical University and the Medical School at Comenius University in Bratislava (from which she received her medical degree). Following graduation, she dedicated herself to internal medicine and medical informatics. She went on to receive her MBA degree at the Business School at University of Leeds, UK. In 2011, she received a Doctor of Sciences (DSc) for her innovative approach to the ECG diagnosis of left ventricular hypertrophy. Her main research interest is the evaluation of the cardiac electric field, from standard 2-lead ECG to modeling, 3D visualization and multimodal imaging. In 2005 she became the executive editor of the Journal of Electrocardiology, and since 2006, she has spearheaded the International Research Interdisciplinary Schools (IRIS). Niraj Varma, MD, PhD, FRCP is Professor of Medicine at Cleveland Clinic, USA. After medical school in Oxford and Edinburgh, he received specialist training in Cambridge, UK and Harvard Medical School, USA. In Boston he undertook research work leading to a PhD. He has over 25 years of clinical experience maintaining research projects; e.g. pioneering the first clinical applications of remote monitoring of implantable devices, electrocardiographic imaging (ECGI), and cardiac resynchronization algorithms. His current interests are the effects of heart size (hypertrophy and shape) in heart failure on pacing therapies. He is past president of theInternational Society for Holter and Noninvasive Electrocardiology (ISHNE), currently serves on the Digital Health Committee of the Heart Rhythm Society (HRS), and is Deputy Editor of Europace journal.

• 1. Introduction2. Electrocardiographic criteria for left ventricular hypertrophy diagnosis3. ST segment strain pattern in left ventricular hypertrophy4. QT interval dynamics in left ventricular hypertrophy5. Epidemiology and prognosis of left ventricular hypertrophy through electrocardiography: from Minnesota Code to artificial intelligence6. Echocardiographic diagnosis of left ventricular hypertrophy and its compatibility with electrocardiographic criteria: the “false negative and false positive” electrocardiography7. Addition of serum biomarkers carboxyterminal propeptide of procollagen type I (PICP) and NT-proBNP levels to electrocardiography criteria for detection of left ventricular hypertrophyl8. The discrepancy between wall thickness, myocardial mass, and ECG appearances in young patients with cardiomyopathies9. Electrocardiographic and echocardiographic differences in the athlete’s heart: a special category10. Electrocardiographic left ventricular hypertrophy and stroke11. Evolving left ventricular hypertrophy: heart failure12. How far should blood pressure be lowered in middle-aged and elderly patients with hypertension and ECG-LVH? Experiences from LIFE and VALUE13. Surgical approaches in hypertrophic cardiomyopathy treatment14. Genetic factors influencing clinical phenotype and electrocardiographic features in left ventricular hypertrophy15. Artificial intelligence for detecting left ventricular hypertrophy using electrocardiography16. Technical considerations in the automated ECG diagnosis of left ventricular hypertrophy17. Myocardial hypertrophy and ischemia: mechanisms of electrophysiological abnormalities18. Effect of volumetric and conductivity changes in the left ventricle on QRS complex morphology in simulations19. The variety of QRS patterns in left ventricular hypertrophy and their electrophysiological interpretation20. Increased LV mass, electrical remodeling, and surface ECG conduction abnormalities in heart failure: implications for implantable defibrillators and cardiac resynchronization therapy