Dr. Yihua Bei is an Eastern Scholar Distinguished Professor and a Shanghai Young Science and Technology Star. She is the secretary-general of the Shanghai Physiological Society and serves on multiple committees within medical and scientific societies. Dr. Bei is an Associate Editor of Journal of Cardiovascular Translational Research and an editorial board member of the Journal of Molecular and Cellular Cardiology PLUS. Her research, published in Molecular Therapy, Advanced Science, Circulation Research et al. focuses on the survival and proliferation of cardiomyocytes and myocardial protection strategies. Her recent work has been accepted in Circulation which unravels an exercise-responsive transcription factor that promotes cardiomyocyte survival and glucose metabolism during ischemic myocardial injury. She was invited to lead a Special Issue “Metabolic Reprogramming in Cardiovascular Diseases” published in Journal of Cardiovascular Translational Research.Dr. Xiao is the Executive Dean of the School of Life Science, Shanghai University, China. In addition, he is the director of the Key Laboratory of Biomedical Materials and Technology for Organ Regeneration of the Ministry of Education, the director of the Shanghai Organ Regeneration Engineering Technology Research Center, and the head of the Cardiovascular Research Institute of Shanghai University. He is an Associate Editor of Journal of Molecular and Cellular Cardiology and Journal of Cardiovascular Translational Research, and is on the editorial boards of several other notable journals. He has authored or co-authored in journals such as Cell Metabolism, Circulation, Circulation Research, and Nature Communications, etc. His research focuses on heart failure intervention and risk prediction, with a particular emphasis on exercise-induced cardiac regeneration and the identification of novel therapeutic targets. He is also interested in epigenetic and metabolic regulations of cardiac function upon exercise and under pathological conditions.

• Section I: Foundational Concepts: Cardiovascular Physiology and Metabolic Pathways1. Glucose Control2. Lipid Metabolism3. Amino Acid Metabolism and Protein Homeostasis4. Energy Metabolism (Mitochondrial Dysfunction)Section II: Metabolic Regulation and Cardiovascular Diseases5. Metabolic Regulation and Ischemic Heart Disease6. Metabolic Regulation and Hypertrophic Cardiomyopathy7. Metabolic Regulation and Diabetic Cardiomyopathy8. Metabolic Regulation and Heart Failure9. Metabolic Regulation and Genetic Cardiovascular Diseases10. Metabolic Regulation and Cardiac RegenerationSection III: Research Methodologies and Innovations11. Traditional and Novel Experimental Models in Metabolic and Cardiovascular Research12. Emerging Technologies in Metabolic and Cardiovascular Research13. Metabolic Regulation of the Microbiome and Cardiac Function14. Interplays of Metabolism and Epigenetics in Cardiovascular DiseasesSection IV: Therapeutic Approaches and Clinical Implications15. Pharmacological Interventions of Metabolic Therapies16. Diet and Nutrition Modifications for Cardiovascular Health17. Exercise and Cardiovascular Metabolism Conclusion

Dr. Yihua Bei is an Eastern Scholar Distinguished Professor and a Shanghai Young Science and Technology Star. She is the secretary-general of the Shanghai Physiological Society and serves on multiple committees within medical and scientific societies. Dr. Bei is an Associate Editor of Journal of Cardiovascular Translational Research and an editorial board member of the Journal of Molecular and Cellular Cardiology PLUS. Her research, published in Molecular Therapy, Advanced Science, Circulation Research et al. focuses on the survival and proliferation of cardiomyocytes and myocardial protection strategies. Her recent work has been accepted in Circulation which unravels an exercise-responsive transcription factor that promotes cardiomyocyte survival and glucose metabolism during ischemic myocardial injury. She was invited to lead a Special Issue “Metabolic Reprogramming in Cardiovascular Diseases” published in Journal of Cardiovascular Translational Research.Dr. Xiao is the Executive Dean of the School of Life Science, Shanghai University, China. In addition, he is the director of the Key Laboratory of Biomedical Materials and Technology for Organ Regeneration of the Ministry of Education, the director of the Shanghai Organ Regeneration Engineering Technology Research Center, and the head of the Cardiovascular Research Institute of Shanghai University. He is an Associate Editor of Journal of Molecular and Cellular Cardiology and Journal of Cardiovascular Translational Research, and is on the editorial boards of several other notable journals. He has authored or co-authored in journals such as Cell Metabolism, Circulation, Circulation Research, and Nature Communications, etc. His research focuses on heart failure intervention and risk prediction, with a particular emphasis on exercise-induced cardiac regeneration and the identification of novel therapeutic targets. He is also interested in epigenetic and metabolic regulations of cardiac function upon exercise and under pathological conditions.

• Section I: Foundational Concepts: Cardiovascular Physiology and Metabolic Pathways1. Glucose Control2. Lipid Metabolism3. Amino Acid Metabolism and Protein Homeostasis4. Energy Metabolism (Mitochondrial Dysfunction)Section II: Metabolic Regulation and Cardiovascular Diseases5. Metabolic Regulation and Ischemic Heart Disease6. Metabolic Regulation and Hypertrophic Cardiomyopathy7. Metabolic Regulation and Diabetic Cardiomyopathy8. Metabolic Regulation and Heart Failure9. Metabolic Regulation and Genetic Cardiovascular Diseases10. Metabolic Regulation and Cardiac RegenerationSection III: Research Methodologies and Innovations11. Traditional and Novel Experimental Models in Metabolic and Cardiovascular Research12. Emerging Technologies in Metabolic and Cardiovascular Research13. Metabolic Regulation of the Microbiome and Cardiac Function14. Interplays of Metabolism and Epigenetics in Cardiovascular DiseasesSection IV: Therapeutic Approaches and Clinical Implications15. Pharmacological Interventions of Metabolic Therapies16. Diet and Nutrition Modifications for Cardiovascular Health17. Exercise and Cardiovascular Metabolism Conclusion