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    1. Medicin
    2. Medicin: icke kliniska discipliner
    3. Fysiologi

    Redox Signaling in Wound Healing in Elderly Populations: Clinical Approach, Part 2

    AvCakatay,Ufu

    Inbunden, Engelska, 2025

    Del 3 i serien Advances in Biogerontology

    1 881 kr

    Beställningsvara. Skickas inom 10-15 vardagar. Fri frakt över 249 kr.

    Beskrivning

    Redox Signaling in Wound Healing in Elderly Populations: Clinical Approach, Part Two, Volume Three covers wounds in different types and locations (diabetic, ischemic, post-operational) in subcellular and macro dimensions, examining their relationship with aging with an aim to target deteriorating redox signaling cascades and highlight promising therapeutic approaches. Understanding the indication for the use of new therapeutics targeting the illuminated pathways in wound healing helps adjust treatment regimens befitting modern medicine. Ineffective redox adaptation and disseminated oxidative injury are the hallmarks of continuing oxidative stress.

    However, oxidative stress cannot be simply described as the imbalance between ROS formation and antioxidant defense capacity. This also covers impairment in redox sensing and signaling pathways. The term oxidative stress is an expression that is losing its use in modern redox biology. It is now an accepted fact that ROS cannot be described as an apparent enemy or friend. Its optimum level modulates signal transduction and stress responses by acting as a second messenger for redox-sensitive cascades.

    • Provides the only source that accounts for all of the intracellular and intercellular redox homeostasis, cascades, and mechanisms of wound healing in elderly people
    • Deals with wounds in different types and locations (diabetic, ischemic, post-operational) in subcellular and macro dimensions
    • Examines wound healing and its relationship with aging
    • Helps adjust redox-based treatment regimens befitting modern medicine

    Produktinformation

    • Utgivningsdatum:2025-01-20
    • Mått:152 x 229 x 21 mm
    • Vikt:680 g
    • Format:Inbunden
    • Språk:Engelska
    • Serie:Advances in Biogerontology
    • Antal sidor:338
    • Förlag:Elsevier Science
    • ISBN:9780443345159

    Utforska kategorier

    • Fysiologi inom Medicin
    • Geriatrik inom Medicin

    Mer om författaren

    Ufuk Çakatay (May 09, 1965 –) is a Turkish biochemist and biogerontologist. He is a full professor of medical biochemistry at Istanbul-University Cerrahpaşa in Istanbul, Turkey. He has a long-standing interest in oxidative protein damage, redox signaling, and biomarkers of proteostasis. Much less is known about the relationship between redox signaling events and senescent cells. However, it has been shown that the number of senescent cells in many tissues increases with age and that senescent cells are found in various age-related diseases. The development of experimental animal models for age-related disorders and the optimization of various bioanalytical techniques for the assessment of redox status in aging tissue are among his major research interests. Professor Çakatay has authored more than 100 publications in several leading journals, including research papers, book chapters, editorials, and invited reviews on free radical biology, aging, diabetes, redox signaling, and senotherapeutics. He has been a guest editor, reviewer, and editorial board member for more than 50 journals. In addition, Professor Çakatay has a keen interest in mentoring medical students and promoting their research careers. He has received several prestigious awards, including the Top Reviewer Award from Elsevier Science Publishing, and was a former member of the Animal Research and Ethics Committee of Istanbul University. Dr. Atayik is currently working in the Department of General Surgery at Hacettepe University Faculty of Medicine. He has been working as a scientist and researcher with Prof. Ufuk Çakatay since 2017. His research interests are in the fields of aging, age-related disorders, redox biology, oncogenetics, melatonin, mitochondria, surgical advances, and developing novel techniques for modern surgery. Dr. Atayik has conducted clinical research and experimental studies. He has published many scientific papers, such as research papers, narrative reviews, and book chapters, and has worked as an author, referee, editorial assistant, and guest editor, and editor in many prominent publishing houses. He was awarded the Young Investigator Presentation Prize at the VIII. International Congress of Molecular Medicine, which was held in Istanbul, Turkey, in November 2021.

    Innehållsförteckning

    • 1. Redox state of aging skin: A double-edged sword in wound healingQian Chen, Alex Sophabmixay, Thomas Albertson, Gabby Ghasb, Anna Terzian, Lloyd Yan, Lindon Young and Robert Barsotti2. Redox signaling in pressure ulcers within older population: Role of the of antioxidants in their prevention and managementCatalina Rojas-Solé, Víctor Pinilla-González, José Lillo-Moya and Ramón Rodrigo3. Redox signaling in intestinal mucosal wound healingPavel Marković and Jan Homolak4. Gastrointestinal system senility, postsurgical wound healing, and redox signaling pathwaysAnıl Orhan and Süleyman Demiryas5. Redox signaling in age-related vascular disease and wound healingTamer Cebe, Fatih Kızılyel and Bülend Ketenci6. Redox signaling in age-related ocular diseases and healingAhmad Kunbaz7. ROS-mediated redox signaling in diabetic wound healingSaeideh Momtaz and Mohammad Abdollahi8. Nanotherapeutic approach for diabetic wound healing: Cross-talk between redox moleculesMuhammad Asim, Saadiya Zia, Haroon Ur Rashid, Abdul Nasir and Fatma Hussain9. Cerium oxide-based redox active antioxidant and anti-inflammatory biomaterial for wound healing applicationsAnkitha Suresh, Meghna Shetty and Bhisham Narayan Singh10. The redox signaling of ozone in wound repair in the elderly. Perspectives for a thorough review about oxygen-ozone adjunct therapy in traumatic and post-surgical woundsSalvatore Chirumbolo, Marianno Franzini, Umberto Tirelli, Sergio Pandolfi, Giovanni Ricevuti, Francesco Vaiano, Marianna Chierchia and Luigi Valdenassi11. Contemporary redox-related therapeutic approach to burn wounds in the elderlyMehmet Kaan Akgün, Sara Koçi, Mehmet Can Atayik and Ömer Cennet
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