The Glutamate Synapse as a Therapeutic Target

Inbunden, Engelska, 1998

Del 116 i serien Progress in Brain Research

3 013 kr

Beställningsvara. Skickas inom 10-15 vardagar. Fri frakt över 249 kr.

Beskrivning

This volume provides a comprehensive update on basic glutamate research, from a clinical perspective. Thus, emphasis is placed on how the different molecular players at the glutamate synapse interact to produce a postsynaptic response, how synaptic transmission is perturbed in epilepsy and other pathological conditions, and how glutamate may acquire toxic properties and lead to acute or chronic neurodegeneration. Promising targets for therapeutic strategies are discussed.

A coherent picture is provided of the glutamate synapse and its molecular organization. The book therefore deals with each step in the signal process, from synthesis and vesicular uptake of glutamate to its clearance following receptor activation.

Produktinformation

Utgivningsdatum:1998-11-09
Mått:152 x 229 x 0 mm
Vikt:1 430 g
Format:Inbunden
Språk:Engelska
Serie:Progress in Brain Research
Antal sidor:462
Förlag:Elsevier Science
ISBN:9780444827548

Utforska kategorier

Neurologi och klinisk neurofysiologi inom Medicin

Innehållsförteckning

I. Glutamate Release and Transport.II. Glutamate Synthesis and Translocation to Vesicles. III. Glutamate Receptors. IV. Glutamate Toxicity and Cell Death in the Cental Nervous System. V. Conditions of Perturbed Glutamatergic Transmission.VI. Perspectives.