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    Mizoroki-Heck Reaction

    AvMartin Oestreich

    Inbunden, Engelska, 2009

    2 169 kr

    Beställningsvara. Skickas inom 5-8 vardagar. Fri frakt över 249 kr.

    Beskrivning

    Exploring the importance of Richard F. Heck’s carbon coupling reaction, this book highlights the subject of the 2010 Nobel Prize in Chemistry for palladium-catalyzed cross couplings in organic synthesis, and includes a foreword from Nobel Prize winner Richard F. Heck. The Mizoroki-Heck reaction is a palladium-catalyzed carbon–carbon bond forming process which is widely used in organic and organometallic synthesis. It has seen increasing use in the past decade as chemists look for strategies enabling the controlled construction of complex carbon skeletons. The Mizoroki-Heck Reaction is the first dedicated volume on this important reaction, including topics on: mechanisms of the Mizoroki-Heck reactionintermolecular Mizoroki-Heck reactionsfocus on regioselectivity and product outcome in organic synthesiswaste-minimized Mizoroki-Heck reactionsintramolecular Mizoroki-Heck reactionsformation of heterocycleschelation-controlled Mizoroki-Heck reactionsthe Mizoroki-Heck reaction in domino processesoxidative heck-type reactions (Fujiwara-Moritani reactions)Mizoroki-Heck reactions with metals other than palladiumligand design for intermolecular asymmetric Mizoroki-Heck reactionsintramolecular enantioselective Mizoroki-Heck reactionsdesymmetrizing Mizoroki-Heck reactionsapplications in combinatorial and solid phase syntheses, and the development of modern solvent systems and reaction techniquesthe asymmetric intramolecular Mizoroki-Heck reaction in natural product total synthesisSeveral chapters are devoted to asymmetric Heck reactions with particular focus on the construction of otherwise difficult-to-obtain sterically congested tertiary and quaternary carbons. Industrial and academic applications are highlighted in the final section. The Mizoroki-Heck Reaction will find a place on the bookshelves of any organic or organometallic chemist.“I am convinced that this book will rapidly become the most important reference text for research chemists in academia and industry who seek orientation in the rapidly growing and – for the layman – confusing field described as the “’Mizoroki–Heck reaction’.” (Synthesis, March 2010)

    Produktinformation

    • Utgivningsdatum:2009-02-20
    • Mått:168 x 244 x 38 mm
    • Vikt:1 162 g
    • Format:Inbunden
    • Språk:Engelska
    • Antal sidor:608
    • Förlag:John Wiley & Sons Inc
    • ISBN:9780470033944

    Utforska kategorier

    • Organisk kemi inom Naturvetenskap och teknik

    Mer om författaren

    Martin Oestreich (born in 1971 in Pforzheim/Germany) is currently Professor of Organic Chemistry at the Technische Universität Berlin. He received his diploma degree with Paul Knochel (Marburg, 1996) and his doctoral degree with Dieter Hoppe (Münster, 1999). After a two-year postdoctoral stint with Larry E. Overman (Irvine, 1999-2001), he completed his habilitation with Reinhard Brückner (Freiburg, 2001-2005) and was appointed as Professor of Organic Chemistry at the Westfälische Wilhelms-Universität Münster (2006-2011). He also held visiting positions at Cardiff University in Wales (2005) and at The Australian National University in Canberra (2010).

    Recensioner i media

    "It is by far the most authoritative book in this area written to date and has employed many of the major contributors in the area over recent years to provide chapters, resulting in good...coverage of the literature." (Applied Organimetallic Chemistry , March 2010) “I am convinced that this book will rapidly become the most important reference text for research chemists in academia and industry who seek orientation in the rapidly growing and – for the layman – confusing field described as the “’Mizoroki–Heck reaction’.” (Synthesis, March 2010) "This book is a welcome addition to the subject and provides almost all the areas you would want to be covered." (Organic Process Research & Development Journal, 2010)"The selection and clear arrangement of the competently written chapters of this book is well done, giving a rapid general overview of current knowledge about various aspects of this important reaction." (Angewandte Chemie December 2009)

    Innehållsförteckning

    • Foreword by Professor Richard F. Heck 1 Mechanisms of the Mizoroki–Heck ReactionAnny Jutand2 Focus on Catalyst Development and Ligand DesignIrina P. Beletskaya and Andrei V. Cheprakov3 Focus on Regioselectivity and Product Outcome in Organic SynthesisPeter Nilsson, Kristofer Olofsson and Mats Larhed4 Waste-Minimized Mizoroki–Heck ReactionsLukas Gooßen and Käthe Gooßen5 Formation of CarbocyclesAxel B. Machotta and Martin Oestreich6 Formation of HeterocyclesThierry Muller and Stefan Bräse7 Chelation-Controlled Mizoroki–Heck ReactionsKenichiro Itami and Jun-ichi Yoshida8 The Mizoroki–Heck Reaction in Domino ProcessesLutz F. Tietze and Laura M. Levy9 Oxidative Heck-Type Reactions (Fujiwara–Moritani Reactions)Eric M. Ferreira, Haiming Zhang and Brian M. Stoltz10 Mizoroki–Heck Reactions with Metals Other than PalladiumLutz Ackermann and Robert Born11 Ligand Design for Intermolecular Asymmetric Mizoroki–Heck ReactionsAnthony G. Coyne, Martin O. Fitzpatrick and Patrick J. Guiry12 Intramolecular Enantioselective Mizoroki–Heck ReactionsJames T. Link and Carol K. Wada13 Desymmetrizing Heck ReactionsMasakatsu Shibasaki and Takashi Ohshima14 Combinatorial and Solid-Phase SynthesesThierry Muller and Stefan Bräse15 Mizoroki–Heck Reactions: Modern Solvent Systems and Reaction TechniquesWerner Bonrath, Ulla L´etinois, Thomas Netscher and Jan Schütz16 The Asymmetric Intramolecular Mizoroki–Heck Reaction in Natural Product Total SynthesisAmy B. Dounay and Larry E. Overman