PETER J. H. SCOTT is an Assistant Professor in the Department of Radiology at the University of Michigan Medical School. Dr. Scott edited Linker Strategies in Solid-Phase Organic Synthesis (also from Wiley) and is the Series Editor for both the Wiley Series on Radiochemical Syntheses and the Wiley Series on Solid-Phase Organic Syntheses.

“Overall, though, the adoption of an Organic Synthesesstyle is an excellent idea and works very well. Along with other related volumes, this collection serves to demystify polymer-supported methods for palladium-catalysed reactions and provides a very useful collection of clear methods.  It will certainly be of interest and use to those new to the fi eld.”  (Platinum Metals Review, 1 July 2013)

• Contributors ixPreface xiiiAbbreviations xvPART I INTRODUCTION 11. An Introduction to Solid-Phase Palladium Chemistry 3Carmen GilPART II PALLADIUM-MEDIATED SPOS 232. Pd-Catalyzed Solid-Phase Decoration of the 2(1H)-Pyrazinone Scaffold 25Vaibhav P. Mehta and Erik V. Van der Eycken3. One-Step Palladium- and Phenylsilane-Activated Amidation of Solid-Supported Ally Esters 35Zheming Ruan, Katy Van Kirk, Christopher B. Cooper, R. Michael Lawrence, and Michael Poss4. Solid-Phase Reactions of Polymer-Bound Arenesulfonates with Aryl Grignard Reagents 41Kwangyong Park and Chul-Hee Cho5. Fluorous Synthesis of 3-Aminoimidazo[1,2-a]-Pyridine/Pyrazine Library 51Wei Zhang and Yimin Lu6. Resin-to-Resin Transfer Reactions (RRTR) via Sonogashira Coupling 59Judit Tulla-Puche, Rita S. Majerle, Fernando Albericio, and George BaranyPART III IMMOBILIZED CATALYSTS AND LIGANDS 677. Polymer-supported Palladium Catalysts for Suzuki and Heck Reactions 69Peter Styring8. Solid-Phase Catalytic Activity of a Polymer-Supported Palladium Complex 79Maria M. Dell’Anna, Piero Mastrorilli, and Cosimo F. Nobile9. Polyaniline-immobilized Palladium for Suzuki-Miyaura Coupling Reaction in Water 87Moumita Roy, Pravin R. Likhar, and M. Lakshmi Kantam10. Synthesis of Polymer-Supported Aryldicyclohexylphosphine for an Efficient Recycling in Suzuki-Miyaura Reactions 91Katarzyna Glegola and Eric Framery11. C–C or C–N Reactions Catalyzed by Diadamanthylphosphine Palladium-Based Catalyst Supported on Dab-Dendrimers 97Karine Heuzé, Agnés Fougeret, Julietta Lemo, and Daniel Rosario-AmorinPART IV PALLADIUM-MEDIATED MULTIFUNCTIONAL CLEAVAGE 10512. Solid-Phase Reactions of Resin-Supported Boronic Acids 107François Carreaux, Bertrand Carboni, Herve Deleuze, and Christelle Pourbaix-L’Ebraly13. A Simple Diversity Linker Strategy Using Immobilized Enol Phosphonates as Electrophiles for Suzuki-Miyaura Reactions 119Tom M. Woods14. Heck Cleavage of Resin-bound Triazenes 129Sylvia Vanderheiden, Nicole Jung, and Stefan Bräse15. Pd-Mediated Cleavage from Tetrafluoroarylsulfonate Linker Units 139Andrew N. Cammidge and Zainab Ngaini16. Palladium-Catalyzed Solid-Phase Synthesis of Allylic Amines 145Richard C. D. Brown and Martin L. Fisher17. Palladium-Catalyzed Solid-Phase Synthesis of 4-Methylene Pyrrolidines 157Lynda J. Brown, Richard C. D. Brown, and Martin L. FisherIndex 167

PETER J. H. SCOTT is an Assistant Professor in the Department of Radiology at the University of Michigan Medical School. Dr. Scott edited Linker Strategies in Solid-Phase Organic Synthesis (also from Wiley) and is the Series Editor for both the Wiley Series on Radiochemical Syntheses and the Wiley Series on Solid-Phase Organic Syntheses.

“Overall, though, the adoption of an Organic Synthesesstyle is an excellent idea and works very well. Along with other related volumes, this collection serves to demystify polymer-supported methods for palladium-catalysed reactions and provides a very useful collection of clear methods.  It will certainly be of interest and use to those new to the fi eld.”  (Platinum Metals Review, 1 July 2013)

• Contributors ixPreface xiiiAbbreviations xvPART I INTRODUCTION 11. An Introduction to Solid-Phase Palladium Chemistry 3Carmen GilPART II PALLADIUM-MEDIATED SPOS 232. Pd-Catalyzed Solid-Phase Decoration of the 2(1H)-Pyrazinone Scaffold 25Vaibhav P. Mehta and Erik V. Van der Eycken3. One-Step Palladium- and Phenylsilane-Activated Amidation of Solid-Supported Ally Esters 35Zheming Ruan, Katy Van Kirk, Christopher B. Cooper, R. Michael Lawrence, and Michael Poss4. Solid-Phase Reactions of Polymer-Bound Arenesulfonates with Aryl Grignard Reagents 41Kwangyong Park and Chul-Hee Cho5. Fluorous Synthesis of 3-Aminoimidazo[1,2-a]-Pyridine/Pyrazine Library 51Wei Zhang and Yimin Lu6. Resin-to-Resin Transfer Reactions (RRTR) via Sonogashira Coupling 59Judit Tulla-Puche, Rita S. Majerle, Fernando Albericio, and George BaranyPART III IMMOBILIZED CATALYSTS AND LIGANDS 677. Polymer-supported Palladium Catalysts for Suzuki and Heck Reactions 69Peter Styring8. Solid-Phase Catalytic Activity of a Polymer-Supported Palladium Complex 79Maria M. Dell’Anna, Piero Mastrorilli, and Cosimo F. Nobile9. Polyaniline-immobilized Palladium for Suzuki-Miyaura Coupling Reaction in Water 87Moumita Roy, Pravin R. Likhar, and M. Lakshmi Kantam10. Synthesis of Polymer-Supported Aryldicyclohexylphosphine for an Efficient Recycling in Suzuki-Miyaura Reactions 91Katarzyna Glegola and Eric Framery11. C–C or C–N Reactions Catalyzed by Diadamanthylphosphine Palladium-Based Catalyst Supported on Dab-Dendrimers 97Karine Heuzé, Agnés Fougeret, Julietta Lemo, and Daniel Rosario-AmorinPART IV PALLADIUM-MEDIATED MULTIFUNCTIONAL CLEAVAGE 10512. Solid-Phase Reactions of Resin-Supported Boronic Acids 107François Carreaux, Bertrand Carboni, Herve Deleuze, and Christelle Pourbaix-L’Ebraly13. A Simple Diversity Linker Strategy Using Immobilized Enol Phosphonates as Electrophiles for Suzuki-Miyaura Reactions 119Tom M. Woods14. Heck Cleavage of Resin-bound Triazenes 129Sylvia Vanderheiden, Nicole Jung, and Stefan Bräse15. Pd-Mediated Cleavage from Tetrafluoroarylsulfonate Linker Units 139Andrew N. Cammidge and Zainab Ngaini16. Palladium-Catalyzed Solid-Phase Synthesis of Allylic Amines 145Richard C. D. Brown and Martin L. Fisher17. Palladium-Catalyzed Solid-Phase Synthesis of 4-Methylene Pyrrolidines 157Lynda J. Brown, Richard C. D. Brown, and Martin L. FisherIndex 167

PETER J. H. SCOTT is an Assistant Professor in the Department of Radiology at the University of Michigan Medical School. Dr. Scott edited Linker Strategies in Solid-Phase Organic Synthesis (also from Wiley) and is the Series Editor for both the Wiley Series on Radiochemical Syntheses and the Wiley Series on Solid-Phase Organic Syntheses.

“Overall, though, the adoption of an Organic Synthesesstyle is an excellent idea and works very well. Along with other related volumes, this collection serves to demystify polymer-supported methods for palladium-catalysed reactions and provides a very useful collection of clear methods.  It will certainly be of interest and use to those new to the fi eld.”  (Platinum Metals Review, 1 July 2013)

• Contributors ixPreface xiiiAbbreviations xvPART I INTRODUCTION 11. An Introduction to Solid-Phase Palladium Chemistry 3Carmen GilPART II PALLADIUM-MEDIATED SPOS 232. Pd-Catalyzed Solid-Phase Decoration of the 2(1H)-Pyrazinone Scaffold 25Vaibhav P. Mehta and Erik V. Van der Eycken3. One-Step Palladium- and Phenylsilane-Activated Amidation of Solid-Supported Ally Esters 35Zheming Ruan, Katy Van Kirk, Christopher B. Cooper, R. Michael Lawrence, and Michael Poss4. Solid-Phase Reactions of Polymer-Bound Arenesulfonates with Aryl Grignard Reagents 41Kwangyong Park and Chul-Hee Cho5. Fluorous Synthesis of 3-Aminoimidazo[1,2-a]-Pyridine/Pyrazine Library 51Wei Zhang and Yimin Lu6. Resin-to-Resin Transfer Reactions (RRTR) via Sonogashira Coupling 59Judit Tulla-Puche, Rita S. Majerle, Fernando Albericio, and George BaranyPART III IMMOBILIZED CATALYSTS AND LIGANDS 677. Polymer-supported Palladium Catalysts for Suzuki and Heck Reactions 69Peter Styring8. Solid-Phase Catalytic Activity of a Polymer-Supported Palladium Complex 79Maria M. Dell’Anna, Piero Mastrorilli, and Cosimo F. Nobile9. Polyaniline-immobilized Palladium for Suzuki-Miyaura Coupling Reaction in Water 87Moumita Roy, Pravin R. Likhar, and M. Lakshmi Kantam10. Synthesis of Polymer-Supported Aryldicyclohexylphosphine for an Efficient Recycling in Suzuki-Miyaura Reactions 91Katarzyna Glegola and Eric Framery11. C–C or C–N Reactions Catalyzed by Diadamanthylphosphine Palladium-Based Catalyst Supported on Dab-Dendrimers 97Karine Heuzé, Agnés Fougeret, Julietta Lemo, and Daniel Rosario-AmorinPART IV PALLADIUM-MEDIATED MULTIFUNCTIONAL CLEAVAGE 10512. Solid-Phase Reactions of Resin-Supported Boronic Acids 107François Carreaux, Bertrand Carboni, Herve Deleuze, and Christelle Pourbaix-L’Ebraly13. A Simple Diversity Linker Strategy Using Immobilized Enol Phosphonates as Electrophiles for Suzuki-Miyaura Reactions 119Tom M. Woods14. Heck Cleavage of Resin-bound Triazenes 129Sylvia Vanderheiden, Nicole Jung, and Stefan Bräse15. Pd-Mediated Cleavage from Tetrafluoroarylsulfonate Linker Units 139Andrew N. Cammidge and Zainab Ngaini16. Palladium-Catalyzed Solid-Phase Synthesis of Allylic Amines 145Richard C. D. Brown and Martin L. Fisher17. Palladium-Catalyzed Solid-Phase Synthesis of 4-Methylene Pyrrolidines 157Lynda J. Brown, Richard C. D. Brown, and Martin L. FisherIndex 167