Professor?Charles Brook is one of the UK and Europe's most prominent endocrinologists. He is Emeritus Professor of Paediatric Endocrinology at University College London and honorary consulting paediatric endocrinologist to Great Ormond Street and University College London Hospitals. He has had over?300 articles published. Professor Mehul Dattani is Academic and Clinical Lead in Endocrinology at Great Ormond Street Hospital for Children (GOSH) and ICH. His?research has led to publications in a number of high impact journals, with 74 articles appearing on PubMed.

• Preface , vii List of Abbreviations, ix1 The Relevance of Molecular Biology to Clinical Practice , 12 Hormones: their Nature, Action and Measurement , 153 The Hypothalamo-Pituitary Axis , 314 Endocrine Problems of Infancy , 485 The Management of Growth Disorders , 706 The Management of Puberty Disorders , 997 The Thyroid Gland , 1298 The Adrenal Gland , 1519 Disorders of Calcium and Bone Metabolism , 17510 Water Balance , 21011 Hypoglycemia , 23012 Obesity and Type 2 Diabetes Mellitus , 24813 Type 1 Diabetes Mellitus , 26714 Endocrine Neoplasia, 29615 Tests and Normal Values in Pediatric Endocrinology , 309Appendix 1: Syndrome-Specific Growth Charts , 325Appendix 2: Normal Values , 337Index, 343

Professor?Charles Brook is one of the UK and Europe's most prominent endocrinologists. He is Emeritus Professor of Paediatric Endocrinology at University College London and honorary consulting paediatric endocrinologist to Great Ormond Street and University College London Hospitals. He has had over?300 articles published. Professor Mehul Dattani is Academic and Clinical Lead in Endocrinology at Great Ormond Street Hospital for Children (GOSH) and ICH. His?research has led to publications in a number of high impact journals, with 74 articles appearing on PubMed.

• Preface , vii List of Abbreviations, ix1 The Relevance of Molecular Biology to Clinical Practice , 12 Hormones: their Nature, Action and Measurement , 153 The Hypothalamo-Pituitary Axis , 314 Endocrine Problems of Infancy , 485 The Management of Growth Disorders , 706 The Management of Puberty Disorders , 997 The Thyroid Gland , 1298 The Adrenal Gland , 1519 Disorders of Calcium and Bone Metabolism , 17510 Water Balance , 21011 Hypoglycemia , 23012 Obesity and Type 2 Diabetes Mellitus , 24813 Type 1 Diabetes Mellitus , 26714 Endocrine Neoplasia, 29615 Tests and Normal Values in Pediatric Endocrinology , 309Appendix 1: Syndrome-Specific Growth Charts , 325Appendix 2: Normal Values , 337Index, 343