Drug Disposition and Pharmacokinetics

• Utgivningsdatum: 2010-10-29
• Språk: Engelska
• ISBN: 9780470665190
• Förlag: John Wiley & Sons Inc
• Mått: 189 x 246 x 15 mm
• Vikt: 666 g

• Farmakologi

Stephen H. Curry is an independent consultant, teacher and writer. With extensive experience of academia and the pharmaceutical industry, he is Professor of Pharmacology and Physiology at the University of Rochester, having held appointments at the University of London, the University of Florida, and with Fisons and AstraZeneca. He has written 4 books and over 150 publications in scientific journals, including prize-winning papers and essays. He was the founding co-editor of the Wiley-Blackwell Journal Biopharmaceutics and Drug Disposition. Robin Whelpton is a senior lecturer at Queen Mary University of London with over thirty years teaching experience. He has written and contributed to a number of books, including co-authoring the successful Fundamentals of Analytical Toxicology published by Wiley-Blackwell in 2008, and published extensively in scientific and technical journals.

"Although there are numerous books on pharmacokinetics, the broad scope and thorough coverage of this one make it an excellent choice, either for a formal class or for self-study.Each topic is carefully presented, from the simplest starting point through increasing levels of complexity.The text provides a unique, balanced approach, examining the specific physical and biological factors affecting the absorption, distribution, metabolism and excretion of drugs, together with mathematical assessment of the concentrations in plasma and body fluids.This readable and informative book is an invaluable resource for professionals and students needing to develop a rational approach to the investigation and application of drugs.The broad scope of this book is intended to support its use by undergraduate, graduate, and professional students new to the field, but also by even experienced biomedical scientists and healthcare professionals as a refresher and reference. These are ambitious goals. The breadth and depth of the treatment of disposition and pharmacokinetics clearly meets the latter goal.All the above quotes are from (Doody’s, 28 October 2012)"The book provides a good breadth of knowledge, and readers will not be overwhelmed by unnecessary detail. For example, complex scientific and mathematical models are conveyed in a remarkably understandable manner that underpin the relevant topic rather than distracts from it. Nineteen chapters are presented in a logical sequence, each with a consistent structure and a number of different subheadings. Up-to-date and relevant references are offered at the end of each chapter, and there is a comprehensive index that is sufficiently detailed to allow readers to easily locate subject topics or worked examples . . .I would have found this book invaluable at an earlier stage of my own career, and consider it to be highly relevant to those engaged in research in either a pharmaceutical industry or academic setting. Drug Disposition and Pharmacokinetics will appeal to students from a range of scientific disciplines including medicine, toxicology, pharmacology and pharmacy. Whilst it is primarily suited to those at a postgraduate or post-doctoral level, it will also be of interest to undergraduates seeking a deeper knowledge than offered by less authoritative compact textbooks." (The British Toxicology Society, 1 May 2011)"This is an authoritative, comprehensive book on the fate of drug molecules in the body, including implications for pharmacological and clinical effects". (HPC Market Watch, 19 January 2011)

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