James C. Pile, MD, FACP, FHM, Thomas E. Baudendistel, MD, FACP, and Brian Harte, MD, FACP, FHM, are all Deputy Editors of the Journal of Hospital Medicine (JHM), and co-editors of JHM's "Clinical Care Conundrum" series since journal inception. Together they have overseen the review process for, reviewed, and in many cases co-authored the CCC's to be included in each journal issue.

“Clinical Care Conundrums is an indispensable reference for hospitalists, hospital-based physicians and midlevel providers, physicians-in-training, and the many other medical practitioners who come up against difficult cases on a daily basis.”  (Kingbook73's Medical Ebook and Video Collection, 15 September 2014)“This book and this format are exceptional. It pushes readers in a way they have not usually experienced since their training days. It is challenging and refreshing at the same time. Congratulations to the editors for bringing a new perspective to life-long learning.”  (Doody’s, 1 November 2013)

• PREFACE ixCONTRIBUTORS xiCHAPTER 1 INTRODUCTION TO CLINICAL CARE CONUNDRUMS IN HOSPITAL MEDICINE 1Robert M. WachterCHAPTER 2 IMPROVING DIAGNOSTIC SAFETY IN HOSPITAL MEDICINE: CAN CLINICAL CARE CONUNDRUMS HELP? 5Edward E. Etchells, Kaveh G. Shojania, and Donald A. RedelmeierCHAPTER 3 CRACKING THE CASE 19Jennei Wei, Patrick P. Kneeland, and Gurpreet DhaliwalCHAPTER 4 A MIDLIFE CRISIS 27Jennifer R. Lukela, Rajesh S. Mangrulkar, Lawrence M. Tierney Jr., John Del Valle, and Sanjay SaintCHAPTER 5 FISHING FOR A DIAGNOSIS 35Colin R. Cooke, John V. L. Sheffield, and Jan V. HirschmannCHAPTER 6 A RASH DECISION 43Brian J. Harte, Gurpreet Dhaliwal, Wendy Armstrong, and James C. PileCHAPTER 7 ONE HUNDRED YEARS LATER 51Thomas E. Baudendistel, Nima Afshar, and Lawrence M. Tierney Jr.CHAPTER 8 THE THIRD TIME’S THE CHARM 59Sara Mekuria, Esteban Cheng Ching, S. A. Josephson, Jinny Tavee, and Brian J. HarteCHAPTER 9 A FRAYED KNOT 69Thomas E. Baudendistel, Irena L. Ilic, and Harry HollanderCHAPTER 10 BETTER LATE THAN NEVER 77Anuradha Ramaswamy, Maytee Boonyapredee, Ramakrishnan Ranganath, Brian J. Harte, and James C. PileCHAPTER 11 THINKING INSIDE THE BOX 87Damon M. Kwan, Gurpreet Dhaliwal, and Thomas E. BaudendistelCHAPTER 12 ARE WE THERE YET? 95Lisa H. Williams, Gregory J. Raugi, Gurpreet Dhaliwal, Sanjay Saint, and Benjamin A. LipskyCHAPTER 13 A DISTINGUISHING FEATURE 105Sanjiv J. Shah, Aubrey O. Ingraham, Sandra Y. Chung, and Richard J. HaberCHAPTER 14 CONSEQUENCES OF MISSED OPPORTUNITIES 113Julia C. Dombrowski, Helen Kao, Natasha Renda, and R. J. KohlwesCHAPTER 15 IN SIGHT BUT OUT OF MIND 121Letizia Attala, Adam Tremblay, Giampaolo Corti, Sanjay Saint, and Alessandro BartoloniCHAPTER 16 A CHANGE OF HEART 127Jonathan P. Piccini, Adrian F. Hernandez, Louis R. Dibernardo, Joseph G. Rogers, and Gurpreet DhaliwalCHAPTER 17 MISSING THE FOREST FOR THE TREES 137Satish Gopal, James C. Pile, and Daniel J. BrotmanCHAPTER 18 A PAIN IN THE BONE 143John Fani Srour, Julia Braza, and Gerald W. SmetanaCHAPTER 19 A DIAGNOSIS OF EXCLUSION 153Iris O. Yung, Thomas E. Baudendistel, and Gurpreet DhaliwalCHAPTER 20 MAKING A LIST AND CHECKING IT TWICE 161Satyen Nichani, Sandro Cinti, and Jeffrey H. BarsukCHAPTER 21 CAUGHT IN THE WEB: E-DIAGNOSIS 169Yasuharu Tokuda, Makoto Aoki, Saurabh B. Kandpal, and Lawrence M. Tierney Jr.CHAPTER 22 IN THE FACE OF IT ALL 177Amit Garg, Thomas E. Baudendistel, and Gurpreet DhaliwalINDEX 185

James C. Pile, MD, FACP, FHM, Thomas E. Baudendistel, MD, FACP, and Brian Harte, MD, FACP, FHM, are all Deputy Editors of the Journal of Hospital Medicine (JHM), and co-editors of JHM's "Clinical Care Conundrum" series since journal inception. Together they have overseen the review process for, reviewed, and in many cases co-authored the CCC's to be included in each journal issue.

“Clinical Care Conundrums is an indispensable reference for hospitalists, hospital-based physicians and midlevel providers, physicians-in-training, and the many other medical practitioners who come up against difficult cases on a daily basis.”  (Kingbook73's Medical Ebook and Video Collection, 15 September 2014)“This book and this format are exceptional. It pushes readers in a way they have not usually experienced since their training days. It is challenging and refreshing at the same time. Congratulations to the editors for bringing a new perspective to life-long learning.”  (Doody’s, 1 November 2013)

• PREFACE ixCONTRIBUTORS xiCHAPTER 1 INTRODUCTION TO CLINICAL CARE CONUNDRUMS IN HOSPITAL MEDICINE 1Robert M. WachterCHAPTER 2 IMPROVING DIAGNOSTIC SAFETY IN HOSPITAL MEDICINE: CAN CLINICAL CARE CONUNDRUMS HELP? 5Edward E. Etchells, Kaveh G. Shojania, and Donald A. RedelmeierCHAPTER 3 CRACKING THE CASE 19Jennei Wei, Patrick P. Kneeland, and Gurpreet DhaliwalCHAPTER 4 A MIDLIFE CRISIS 27Jennifer R. Lukela, Rajesh S. Mangrulkar, Lawrence M. Tierney Jr., John Del Valle, and Sanjay SaintCHAPTER 5 FISHING FOR A DIAGNOSIS 35Colin R. Cooke, John V. L. Sheffield, and Jan V. HirschmannCHAPTER 6 A RASH DECISION 43Brian J. Harte, Gurpreet Dhaliwal, Wendy Armstrong, and James C. PileCHAPTER 7 ONE HUNDRED YEARS LATER 51Thomas E. Baudendistel, Nima Afshar, and Lawrence M. Tierney Jr.CHAPTER 8 THE THIRD TIME’S THE CHARM 59Sara Mekuria, Esteban Cheng Ching, S. A. Josephson, Jinny Tavee, and Brian J. HarteCHAPTER 9 A FRAYED KNOT 69Thomas E. Baudendistel, Irena L. Ilic, and Harry HollanderCHAPTER 10 BETTER LATE THAN NEVER 77Anuradha Ramaswamy, Maytee Boonyapredee, Ramakrishnan Ranganath, Brian J. Harte, and James C. PileCHAPTER 11 THINKING INSIDE THE BOX 87Damon M. Kwan, Gurpreet Dhaliwal, and Thomas E. BaudendistelCHAPTER 12 ARE WE THERE YET? 95Lisa H. Williams, Gregory J. Raugi, Gurpreet Dhaliwal, Sanjay Saint, and Benjamin A. LipskyCHAPTER 13 A DISTINGUISHING FEATURE 105Sanjiv J. Shah, Aubrey O. Ingraham, Sandra Y. Chung, and Richard J. HaberCHAPTER 14 CONSEQUENCES OF MISSED OPPORTUNITIES 113Julia C. Dombrowski, Helen Kao, Natasha Renda, and R. J. KohlwesCHAPTER 15 IN SIGHT BUT OUT OF MIND 121Letizia Attala, Adam Tremblay, Giampaolo Corti, Sanjay Saint, and Alessandro BartoloniCHAPTER 16 A CHANGE OF HEART 127Jonathan P. Piccini, Adrian F. Hernandez, Louis R. Dibernardo, Joseph G. Rogers, and Gurpreet DhaliwalCHAPTER 17 MISSING THE FOREST FOR THE TREES 137Satish Gopal, James C. Pile, and Daniel J. BrotmanCHAPTER 18 A PAIN IN THE BONE 143John Fani Srour, Julia Braza, and Gerald W. SmetanaCHAPTER 19 A DIAGNOSIS OF EXCLUSION 153Iris O. Yung, Thomas E. Baudendistel, and Gurpreet DhaliwalCHAPTER 20 MAKING A LIST AND CHECKING IT TWICE 161Satyen Nichani, Sandro Cinti, and Jeffrey H. BarsukCHAPTER 21 CAUGHT IN THE WEB: E-DIAGNOSIS 169Yasuharu Tokuda, Makoto Aoki, Saurabh B. Kandpal, and Lawrence M. Tierney Jr.CHAPTER 22 IN THE FACE OF IT ALL 177Amit Garg, Thomas E. Baudendistel, and Gurpreet DhaliwalINDEX 185

James C. Pile, MD, FACP, FHM, Thomas E. Baudendistel, MD, FACP, and Brian Harte, MD, FACP, FHM, are all Deputy Editors of the Journal of Hospital Medicine (JHM), and co-editors of JHM's "Clinical Care Conundrum" series since journal inception. Together they have overseen the review process for, reviewed, and in many cases co-authored the CCC's to be included in each journal issue.

“Clinical Care Conundrums is an indispensable reference for hospitalists, hospital-based physicians and midlevel providers, physicians-in-training, and the many other medical practitioners who come up against difficult cases on a daily basis.”  (Kingbook73's Medical Ebook and Video Collection, 15 September 2014)“This book and this format are exceptional. It pushes readers in a way they have not usually experienced since their training days. It is challenging and refreshing at the same time. Congratulations to the editors for bringing a new perspective to life-long learning.”  (Doody’s, 1 November 2013)

• PREFACE ixCONTRIBUTORS xiCHAPTER 1 INTRODUCTION TO CLINICAL CARE CONUNDRUMS IN HOSPITAL MEDICINE 1Robert M. WachterCHAPTER 2 IMPROVING DIAGNOSTIC SAFETY IN HOSPITAL MEDICINE: CAN CLINICAL CARE CONUNDRUMS HELP? 5Edward E. Etchells, Kaveh G. Shojania, and Donald A. RedelmeierCHAPTER 3 CRACKING THE CASE 19Jennei Wei, Patrick P. Kneeland, and Gurpreet DhaliwalCHAPTER 4 A MIDLIFE CRISIS 27Jennifer R. Lukela, Rajesh S. Mangrulkar, Lawrence M. Tierney Jr., John Del Valle, and Sanjay SaintCHAPTER 5 FISHING FOR A DIAGNOSIS 35Colin R. Cooke, John V. L. Sheffield, and Jan V. HirschmannCHAPTER 6 A RASH DECISION 43Brian J. Harte, Gurpreet Dhaliwal, Wendy Armstrong, and James C. PileCHAPTER 7 ONE HUNDRED YEARS LATER 51Thomas E. Baudendistel, Nima Afshar, and Lawrence M. Tierney Jr.CHAPTER 8 THE THIRD TIME’S THE CHARM 59Sara Mekuria, Esteban Cheng Ching, S. A. Josephson, Jinny Tavee, and Brian J. HarteCHAPTER 9 A FRAYED KNOT 69Thomas E. Baudendistel, Irena L. Ilic, and Harry HollanderCHAPTER 10 BETTER LATE THAN NEVER 77Anuradha Ramaswamy, Maytee Boonyapredee, Ramakrishnan Ranganath, Brian J. Harte, and James C. PileCHAPTER 11 THINKING INSIDE THE BOX 87Damon M. Kwan, Gurpreet Dhaliwal, and Thomas E. BaudendistelCHAPTER 12 ARE WE THERE YET? 95Lisa H. Williams, Gregory J. Raugi, Gurpreet Dhaliwal, Sanjay Saint, and Benjamin A. LipskyCHAPTER 13 A DISTINGUISHING FEATURE 105Sanjiv J. Shah, Aubrey O. Ingraham, Sandra Y. Chung, and Richard J. HaberCHAPTER 14 CONSEQUENCES OF MISSED OPPORTUNITIES 113Julia C. Dombrowski, Helen Kao, Natasha Renda, and R. J. KohlwesCHAPTER 15 IN SIGHT BUT OUT OF MIND 121Letizia Attala, Adam Tremblay, Giampaolo Corti, Sanjay Saint, and Alessandro BartoloniCHAPTER 16 A CHANGE OF HEART 127Jonathan P. Piccini, Adrian F. Hernandez, Louis R. Dibernardo, Joseph G. Rogers, and Gurpreet DhaliwalCHAPTER 17 MISSING THE FOREST FOR THE TREES 137Satish Gopal, James C. Pile, and Daniel J. BrotmanCHAPTER 18 A PAIN IN THE BONE 143John Fani Srour, Julia Braza, and Gerald W. SmetanaCHAPTER 19 A DIAGNOSIS OF EXCLUSION 153Iris O. Yung, Thomas E. Baudendistel, and Gurpreet DhaliwalCHAPTER 20 MAKING A LIST AND CHECKING IT TWICE 161Satyen Nichani, Sandro Cinti, and Jeffrey H. BarsukCHAPTER 21 CAUGHT IN THE WEB: E-DIAGNOSIS 169Yasuharu Tokuda, Makoto Aoki, Saurabh B. Kandpal, and Lawrence M. Tierney Jr.CHAPTER 22 IN THE FACE OF IT ALL 177Amit Garg, Thomas E. Baudendistel, and Gurpreet DhaliwalINDEX 185