Comprehensive Organic Transformations, 4 Volume Set

Richard C. Larock, PhD, is Professor Emeritus of Chemistry at Iowa State University. He is a pioneer in the use of palladium catalysts in organic synthesis, particularly in the synthesis of carbocycles and heterocycles. Dr. Larock has given over 420 research presentations and published about 350 articles, 32 patents, and 4 books including two editions of the bestselling classic Comprehensive Organic Transformations (Wiley 1996 and 1999).

• Literature Abbreviations xxxixChemical Abbreviations xlixAlkanes and Arenes 1General References 31. Reduction 52. Coupling Reactions 1933. Friedel-Crafts and Related Alkylation Reactions 3434. Ring-Forming Reactions 3555. Aromatization 467Alkenes 519General References 5211. Isomerization of Alkenes 5232. Elimination 5713. Alkylidenation of Carbonyl and Related Compounds 6454. Wittig and Related Reactions 6615. Metal-Promoted Coupling Reactions 6936. Arene, Alkyne, and Diene Addition Reactions 7677. Dienes and Polyenes 8798. Diels–Alder Reactions 10179. Cyclization, Annulation, and Related Reactions 1105Alkynes 1143General References 11451. Isomerization and Metathesis 11472. Elimination Reactions 11513. Wittig and Related Approaches 11694. Alkylation, Alkenylation, and Arylation of Alkynes and Allenes 1175Halides 1231General References 12331. Halogenation of Hydrocarbons 12373. Halogenation of Alkenes and Dienes 12694. Halogenation of Alkynes 13135. Interconversion of Halides 13336. Halogenation of Nitrogen Compounds 13457. Halogenation of Ethers 13558. Halogenation of Alcohols 13619. Halogenation of Phenols 138510. Halogenation of Sulfur and Selenium Compounds 138711. Halogenation of Carbonyl and Related Compounds 139712. Halodecarboxylation and Decarbonylation of Acids and Derivatives 145913. Halogenation of Organometallics 1467Amines 1479General References 14811. From Alkanes 14832. From Arenes 14873. From Alkenes, Dienes, and Alkynes 14914. From Alkyl and Aryl Halides Or Sulfonates 15295. From Other Amines and Derivatives 15456. From Azides 15957. From Nitro Compounds 16058. Heteroatom and Metal Substitution 16179. From Ethers, Alcohols, and Derivatives 162110. From Aldehydes, Ketones, and Derivatives 163111. From Carboxylic Acids and Derivatives 169712. From Nitriles 170913. From Isonitriles and Azo Compounds 1715Ethers 1717General References 17191. From Other Ethers 17212. Alkylation of Alcohols, Phenols, and Derivatives 17433. Alkane, Arene, Alkene, and Alkyne Substitutions and Additions 18594. Acetal, Carbonyl, and Ortho Ester Conversions 19635. Miscellaneous Reactions 2053Alcohols and Phenols 2057General References 20591. Resolution 20612. Alcohol Transposition 20673. Substitution 20714. Oxidation 20835. Alkene, Diene, and Alkyne Additions 21076. Organoboranes 21437. Ether Cleavage 21638. Reduction 22699. Alkylation of Carbonyl Compounds 233910. Miscellaneous Reactions 2437Aldehydes and Ketones 2439General References 24411. Carbonyl Transposition 24432. Oxidation 24493. Reduction of Phenols, Carboxylic Acids and Derivatives, and Nitriles 25874. Rearrangements 26055. Condensation Reactions 26876. Cyclization and Annulation Reactions 27217. Carbonylation and Related Reactions 27838. Electrophilic Acylation 28319. Nucleophilic Acylation 292710. Sulfur, Selenium, and Tellurium Reagents 294911. Heterocycles 296112. Carbonyl Homologation 296913. Alkylation and Acylation of Aldehydes, Ketones,And Their Derivatives 298115. 1,4-Addition To Α,Β-Unsaturated Carbonyl Compounds and Derivatives 3141Nitriles, Carboxylic Acids, and Derivatives 3243General References 32451. Oxidation, Substitution, and Addition 32472. Reduction 33313. Carbonylation, Carboxylation, and Related Reactions 33354. Carbonyl Homologation and Degradation 33995. Alkylation, Acylation, and Substitution of Nitriles, Carboxylic Acids, and Derivatives 34096. Conjugate Addition To Α,Β-Unsaturated Nitriles, Carboxylic Acids, and Derivatives 35497. Rearrangements 36198. Lactone and Lactam Formation 36479. Interconversion of Nitriles, Carboxylic Acids, and Derivatives 374910. Miscellaneous Reactions 3831