Apoptosis and the Immune System

Inbunden, Engelska, 1995

3 071 kr

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Beskrivning

Apoptosis and the Immune Response Edited by Christopher D. Gregory In this timely and important work, an international group ofleading investigators takes a close and critical look at programmedcell death and its role in the development, function, andmaintenance of the immune system. Along with covering the primaryactions of apoptosis, the contributors probe its role incarcinogenesis and HIV-induced pathogenesis. By offering a broadrange of views, Apoptosis and the Immune Response presents acurrent and complete picture of the various aspects andconsequences of this phenomenon. Apoptosis and the Immune Response begins with the theoriessurrounding apoptosis and then covers its basic mechanismsincluding the morphologic, biochemical, and genetic features. Thebook offers authoritative discussions on the role of apoptosis inthe deletion of self-reactive lymphocytes, prevention ofautoimmunity, termination of the immune response, death of T cellsinfected by the HIV virus, neoplasia, and the homeostaticregulation of the hematopoietic system. In particular, this excellent reference critiques such topics as:* Apoptosis in thymocytes in vivo and in vitro* Bcl-2/T-cell transgenics* The role of c-myc* Fas/APO-1 antigens and their roles* Transgenic models of B-cell tolerance and autoimmunity* How apoptosis affects the pathogenesis of AIDS and theimplications for therapy* Triggers for apoptosis and survival* Recognition of apoptotic cells by phagocytes* Apoptosis in peritoneal autoreactive CD5+ B cells* and more With its diverse expertise and timely, clear-cut insights,Apoptosis and the Immune Response will prove to be an invaluableresource for immunologists, cell and developmental biologists,hematologists, and oncologists--as well as graduate students. Cover Design: Janice Noto-Helmers

Produktinformation

Utgivningsdatum:1995-03-29
Mått:163 x 244 x 24 mm
Vikt:794 g
Format:Inbunden
Språk:Engelska
Antal sidor:432
Förlag:John Wiley & Sons Inc
ISBN:9780471012511

Utforska kategorier

Onkologi inom Medicin
Cellbiologi inom Naturvetenskap och teknik

Mer om författaren

Christopher D. Gregory is the author of Apoptosis and the Immune System, published by Wiley.

Innehållsförteckning

Partial table of contents: Apoptosis in the Immune System: Concepts and Questions (G.Williams). Apoptosis in Intrathymic T-Cell Development (P. Kisielow). HIV Infection and T-Cell Death (J. Ameisen). Fas/APO-1: A Cell Surface Receptor that Signals Apoptosis (P. Cohen& R. Eisenberg). Apoptosis in Immature B Lymphocytes (D. Scott). Control of Apoptosis in Human B Cells: Implications for Neoplasia(C. Gregory). The Innate Immune System: Recognition of Apoptotic Cells (J.Savill). Apoptosis in the Hematopoietic System (L. Sachs & J.Lotem). Index.

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Apoptosis and the Immune System

AvChristopher D. Gregory

Inbunden, Engelska, 1995

3 071 kr

Tillfälligt slut

Beskrivning

Produktinformation

Utgivningsdatum:1995-03-29
Mått:163 x 244 x 24 mm
Vikt:794 g
Format:Inbunden
Språk:Engelska
Antal sidor:432
Förlag:John Wiley & Sons Inc
ISBN:9780471012511

Utforska kategorier

Onkologi inom Medicin
Cellbiologi inom Naturvetenskap och teknik

Mer om författaren

Christopher D. Gregory is the author of Apoptosis and the Immune System, published by Wiley.

Innehållsförteckning

Partial table of contents: Apoptosis in the Immune System: Concepts and Questions (G.Williams). Apoptosis in Intrathymic T-Cell Development (P. Kisielow). HIV Infection and T-Cell Death (J. Ameisen). Fas/APO-1: A Cell Surface Receptor that Signals Apoptosis (P. Cohen& R. Eisenberg). Apoptosis in Immature B Lymphocytes (D. Scott). Control of Apoptosis in Human B Cells: Implications for Neoplasia(C. Gregory). The Innate Immune System: Recognition of Apoptotic Cells (J.Savill). Apoptosis in the Hematopoietic System (L. Sachs & J.Lotem). Index.