' … gives excellent insight into new methods still on the test-bed, and offers tantalising glimpses of better methods just around the corner. It will cause every one of us to question whether the program we just ran was the most appropriate means to solve the structure.' David Blow, Crystallography News

• 1. The basics of X-ray diffraction theory; 2. The Patterson and heavy-ion methods; 3. Direct methods; 4. The basics of isomorphous replacement and anomalous scattering; 5. Further aspects of the isomorphous replacement method; 6. Use of anomalous scattering data; 7. Phase extension and refinement; 8. Multiple-beam scattering methods; Bibliography; Index.

' … gives excellent insight into new methods still on the test-bed, and offers tantalising glimpses of better methods just around the corner. It will cause every one of us to question whether the program we just ran was the most appropriate means to solve the structure.' David Blow, Crystallography News

• 1. The basics of X-ray diffraction theory; 2. The Patterson and heavy-ion methods; 3. Direct methods; 4. The basics of isomorphous replacement and anomalous scattering; 5. Further aspects of the isomorphous replacement method; 6. Use of anomalous scattering data; 7. Phase extension and refinement; 8. Multiple-beam scattering methods; Bibliography; Index.

' … gives excellent insight into new methods still on the test-bed, and offers tantalising glimpses of better methods just around the corner. It will cause every one of us to question whether the program we just ran was the most appropriate means to solve the structure.' David Blow, Crystallography News

• 1. The basics of X-ray diffraction theory; 2. The Patterson and heavy-ion methods; 3. Direct methods; 4. The basics of isomorphous replacement and anomalous scattering; 5. Further aspects of the isomorphous replacement method; 6. Use of anomalous scattering data; 7. Phase extension and refinement; 8. Multiple-beam scattering methods; Bibliography; Index.