Dr Delva Shamley is a South African graduate and has been in academia for 26 years, 13 of which were spent in the UK. Her training and experience of clinical research comes from Oxford NHS and the Centre for Medical Statistics, Oxford University, UK. Delva has been training and supporting clinicians in Research Methods for many years. She returned to Cape Town in 2011 and started as Deputy Director of the UCT CRC in October of 2013. She has since been appointed as the Director for CRC.

"What I like about this text is the way it tailors the relevant aspects of pathophysiology towards its target audience. The book is well presented with a plethora of relevant diagrams and tables. It is well suited to students and qualified practitioners alike. Reading this book will go a long way in understanding various conditions, how the body deals with them and how our treatment can influence rehabilitation”In Touch, Summer 2007, No. 119.

• Section 1: An Introduction to Disease ProcessesChapter 1: Inflammation, Wounds and Wound HealingChapter 2: The Immune SystemChapter 3Part 1: Malignant Neoplasms Part 2: Radiation Injury to Normal TissuesChapter 4: EndocrinologySection 2: Altered Mobility and ImmobilityChapter 5: Muscle and Connective Tissue - Key Concepts for RehabilitationChapter 6: Muscle DisordersChapter 7: Bone and Joint DisordersChapter 8: Movement and ImmobilityChapter 9: Altered Exercise TolerancePart 1: Cardiovascular RehabilitationPart 2: Pulmonary RehabilitationSection 3: PregnancyChapter 10: Physiology of PregnancySection 4: Disorders of the SystemsChapter 11: The Nervous SystemPart 1: The Pathophysiology of PainPart 2: The Central Nervous SystemPart 3: The Peripheral Nervous SystemPart 4: Nervous System Reorganization Following InjuryChapter 12: The Circulatory System Part 1: Cardiovascular DisordersPart 2: Blood and Haemodynamic DisordersChapter 13: The Respiratory SystemChapter 14: The Urinary SystemPart 1: The Renal System Part 2: The Overactive BladderSection 5: PharmacologyChapter 15: Normal Drug ActionChapter 16: Substance AbusePart 1: Drug Toxicity and OverdosePart 2: Drug Abuse and Dependence