Adjuvant Therapy of Breast Cancer

Inbunden, Engelska, 1992

Del i serien Cancer Treatment and Research

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Beskrivning

The results of randomized trials evaluating the use of early adjuvant systematic treatment for patients with respectable breast cancer provide a rebuttal to those who would argue that little progress has been made in the treatment of cancer. Few subjects have been so systematically studied in the history of medicine and it seems fair to conclude that the value of adjuvant systemic therapy in prolonging the lives of women with breast cancer is more firmly supported by empirical evidence than even the more conventional of primary treatments using various combinations of surgery and radiotherapy. This book reviews the rationale for, results of, special problems and future directions of adjuvant therapy of breast cancer. It also includes an appendix from the Early Breast Cancer Trialists' Collaborative Group (OXford) which lists all of the adjuvant trials which have been closed, as well as the active studies now ongoing.

Produktinformation

Utgivningsdatum:1992-08-31
Mått:155 x 235 x 32 mm
Vikt:885 g
Format:Inbunden
Språk:Engelska
Serie:Cancer Treatment and Research
Antal sidor:464
Upplaga:1992
Förlag:Kluwer Academic Publishers
ISBN:9780792316565

Utforska kategorier

Onkologi inom Medicin

Recensioner i media

'Overall, this book is a useful review Volume containing thoughtful and up-to-date information on the optimal use of adjuvant therapy for breast cancer. It will be a valuable addition to the library of the practicing clinical oncologist.' Journal of the Nat. Cancer Inst. 85:10 1993

Innehållsförteckning

I. Rationale and Methods for Studying Adjuvant Systemic Therapy.- 1. Evolving concepts in the adjuvant systemic therapy of operable breast cancer.- 2. Statistical methods for early breast cancer trials.- II. Results of Clinical Studies.- 3. The nature of the benefit.- 4. Adjuvant endocrine therapy of breast cancer.- 5. Adjuvant chemotherapy of axillary lymph-node-positive breast cancer.- 6. The node-negative problem: To treat or not to treat.- III. Special Problems.- 7. Defining the high-risk breast cancer patient.- 8. Models for weighing benefits and toxicities.- 9. Financial considerations in the use of adjuvant chemotherapy.- 10. The use of adjuvant therapy in patients treated with conservative surgery and radiotherapy.- 11. Treating the relapsed patient.- IV. Future Directions.- 12. Unanswered questions in the adjuvant therapy of breast cancer.- 13. Neoadjuvant chemotherapy.- 14. Altering cell kinetics with endocrine therapy.- 15. Polypeptide growth factors: Their potential value in the management of breast cancer patients.- 16. Immunotherapy of breast cancer.- 17. Breast cancer chemoprevention.- Appendices.- I. Consensus statements from panels convened by The National Cancer Institute in 1980, 1985, 1990.- II. List of completed and ongoing randomized clinical trials addressing questions related to the use of adjuvant systemic therapy to treat resectable breast cancer.