Nucleoside Analogs in Cancer Therapy

Bruce D. Cheson (Edited by) , Michael J. Keating (Edited by) , William Plunkett (Edited by)

"…this volume is the first overview summarising the state of the art of purine analogs. The editors were able to get excellent papers together…recommend[ed] to all haemato-oncologists who treat patients with purine analogs."-Annals of Oncology

• Nucleoside Analogs: Cellular Pharmacology, Mechanisms of Action, and Strategies for Combination Therapy, William Plunkett and Varsha GandhiInduction of Apoptosis by Nucleoside Analogs, Peng Huang and Susan WrightPharmacokinetics of Purine Nucleoside Analogs, Jan Liliemark and Gunnar JuliussonClinical Development of 2'-Deoxycoformycin, Bruce D. Cheson and Michael R. GreverClinical Development of Fludarabine, Axel-R. Hanauske and Daniel D. Von HoffDevelopment of 2-Chlorodeoxyadenosine (2-CdA) as a Chemotherapeutic and Immunosuppressive Drug, Ernest Beutler, Dennis Carson, Robert McMillan, and Robert LongmireDefining the Optimal Dose Schedule of Purine Analogs and Assessment of Response, Jorge E. Cortes and Susan M. O'BrienClinical Trials of the Purine Analogs in Chronic Lymphocytic Leukemia, Michael J. KeatingTreatment of Hairy Cell Leukemia with Nucleoside Analogs, Alan Saven and Lawrence D. PiroClinical Trials with Nucleoside Analogs in Lymphomas, Wolfgang Hiddemann and Christiane Pott-HoeckClinical Trials with Nucleoside Analogs in Other Hematologic Malignancies, Jorge E. Cortes, Hagop Kantarjian, Susan M. O'Brien, and Michael J. KeatingNucleoside Analogs as Radiosensitizing Agents, Vincent Grégoire and Walter N. Hittelman2-Chlorodeoxyadenosine in Nonmalignant Disorders, Ernest Beutler, Dennis Carson, J. C. Sipe, J. S. Romine, Robert McMillan, Z. M. Younossi, V. D. Rodgers, James A. Koziol, and J. ZyroffFludarabine in Nonmalignant Disorders, Ioannis O. Tassiulas, John C. Davis, Jr., Barri J. Fessler, Nobuaki Hama, Thomas A. Fleisher, Howard A. Austin III, and Dimitrios T. BoumpasToxicities Associated with Purine Analog Therapy, Bruce D. Cheson