Carbon Monoxide and Cardiovascular Functions

"The book gives a first rate summary of the mechanisms by which CO exerts its action on vascular smooth muscle…The illustrations and pertinent data are well organized and clear. The book is a good source for graduate or upper division undergraduate courses in pharmacology, physiology, or biochemistry of CO. To my knowledge there are no other books in this subject. 3 stars."- John Buchholz, Ph.D., Loma Linda University, Doody's Notes

• CARBON MONOXIDE AND PHYSIOLOGICAL FUNCTIONS OF THE CARDIOVASCULAR SYSTEM: The Physiological Role of Carbon Monoxide Derived from Heme Oxidation Catalysed by Heme Oxygenase. Carbon Monoxide-Induced Vasorelaxation and the Underlying Mechanisms. Carbon Monoxide and Vascular Smooth Muscle Cell Growth. Signal Transduction Pathways Involved in CO-Induced Vasodilation. Carbon Monoxide, Vascular Contractility, and K+ Channels. Nitric Oxide and the Heme Oxygenase/Carbon Monoxide System. Developmental Biology of Heme Oxygenase and Carbon Monoxide in the Cardiopulmonary System. Carbon Monoxide Signaling in the Heart. CARBON MONOXIDE AND PATHOPHYSIOLOGY OF THE CARDIOVASCULAR SYSTEM: The Heme-Heme Oxygenase-Carbon Monoxide System and Hypertension. Carbon Monoxide and Cardiovascular Inflammation. Human HO-1 Deficiency and Cardiovascular Dysfunction. The Roles of Carbon Monoxide in the Pathogenesis of Diabetes and Its Vascular Complications. Selective Increase in Human Heme Oxygenase-1 Gene Expression Attenuates Development of Hypertension and Increases Body Growth in Spontaneously Hypertensive Rats. TECHNIQUES USED IN CARBON MONOXIDE RESEARCH: Studies on the Development of Carbon Monoxide-Releasing Molecules. Sources, Sinks, and Measurement of Carbon Monoxide.