Michael Fox is Director of the Institute for the study of Animal Problems and Scientific Director of The Humane Society of the United States.

• Introduction Chapter 1 The Laboratory Animal Environment: Room for Concern Chapter 2 Present Standards and Questionable Conditions Chapter 3 Experimental Variables Chapter 4 Social Influences and Pheromones Chapter 5 Social Deprivation and Isolation Effects Chapter 6 Handling, Socialization, and Caretaker Effects Chapter 7 Genotypic and Phenotypic Variables Chapter 8 Alternatives and New Directions Chapter 9 Behavioral and Ethical Aspects of Plain and Suffering in Research Animals Chapter 10 Animal Health and Welfare — Toward the One Medicine Chapter 11 Animal Rights: Ethical Issues and Human Obligations Appendix I Humane Attitudes in Animal Care Appendix II The Control of the Proximate, Especially Behavioral, Environment Appendix III Section of Animal Welfare Act Relevant to the Veterinarian's Role and Judicial Authority Appendix IV Toward A Philosophy of Veterinary Medicine and Animal Care References Index