Tertiary Lymphoid Structures

Methods and Protocols

AvMarie-Caroline Dieu-Nosjean

Inbunden, Engelska, 2024

Del 2864 i serien Methods in Molecular Biology

2 720 kr

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Beskrivning

Chapters guide readers through TLS in cancers, different stages of TLS development, immune function of TLS, molecular, cellular, and imaging methods, and preclinical methods to uncover the function of cells composing TLS in inflammatory situations in humans.

Produktinformation

Utgivningsdatum:2024-11-12
Mått:155 x 235 x 24 mm
Vikt:814 g
Format:Inbunden
Språk:Engelska
Serie:Methods in Molecular Biology
Antal sidor:315
Upplaga:2
Förlag:Springer-Verlag New York Inc.
ISBN:9781071641835

Utforska kategorier

Onkologi inom Medicin

Innehållsförteckning

An introduction to tertiary lymphoid structures in cancer.- Tertiary lymphoid structures in central nervous system disorders.- Maturation of tertiary lymphoid structures.- Mouse Models Enable the Functional Investigation of Tertiary Lymphoid Structures in Cancer.- Home-built imaging-based spatial transcriptomics: Tertiary Lymphoid Structures as a case example.- Methods for selective gene expression profiling in single Tertiary Lymphoid Structure using Laser Capture Microdissection.- Laser Capture Microdissection of Tertiary Lymphoid Structures from Formalin-Fixed Paraffin-Embedded Sections of Canine Cutaneous and Subcutaneous Sarcomas for Nanostring direct RNA counting.- Comparative automated quantification of Tertiary Lymphoid Structures in two distinct mouse models of inflammation.- Imaging mass cytometry to decipher the maturation of tertiary lymphoid structures.- Advancement of techniques for precise visualization and quantification of tertiary lymphoid structure-associated immune cells in tissue samples.- Automated Quantification of Tertiary Lymphoid Structures in Human Tumor Samples Using Immunofluorescence and AI-Powered Analysis Pipeline.- Cancer-Associated Lymphoid Aggregates in Histology Images: Manual and Deep Learning-Based Quantification Approaches.- Method Development for Sorting Immune Cell Populations within Tertiary Lymphoid Structures.- Repertoires and tumor-reactivity analysis of B cell immunoglobulins derived from cancer patients.- Exploring the Role of Tertiary Lymphoid Structures using a mouse model of bacteria-infected lungs.- Tertiary Lymphoid Structures and Immunotherapy: Challenges and Opportunities.