Gregoire Nicolis studied engineering at the Technical University of Athens and received his doctorate in physics from the Université libre de Bruxelles, where he is currently Professor Emeritus at the Center for Nonlinear Phenomena and Complex Systems. His research focuses on the theory of irreversible processes, nonlinear phenomena, and complex systems.Dominique Maes is a Professor at the Institute of Molecular Biology and Biotechnology, Vrije Universiteit Brussel. Her research focuses on microgravity and the crystallization of proteins in space.Series EditorsStuart A. Rice received his master's and doctorate from Harvard University and was a junior fellow at Harvard for two years before joining the faculty of The University of Chicago in 1957, where he is currently the Frank P. Hixon Distinguished Service Professor Emeritus.Aaron R. Dinner received his bachelor's degree and doctorate from Harvard University, after which he conducted postdoctoral research at the University of Oxford and the University of California, Berkeley. He joined the faculty at The University of Chicago in 2003.

• Kinetics and Thermodynamics of Fluctuation-Induced Transitions in Multistable Systems 1By Gregoire Nicolis and Catherine NicolisDynamical Rare Event Simulation Techniques for Equilibrium and Nonequilibrium Systems 27By Titus S. Van ErpConfocal Depolarized Dynamic Light Scattering 61By M. Potenza, T. Sanvito, V. Degiorgio, and M. GiglioThe Two-Step Mechanism and The Solution-Crystal Spinodal for Nucleation of Crystals in Solution 79By Peter G. VekilovExperimental Studies of Two-Step Nucleation During Two-Dimensional Crystallization of Colloidal Particles with Short-Range Attraction 111By John R. Savage, Liquan Pei, and Anthony D. DinsmoreOn the Role of Metastable Intermediate States in the Homogeneous Nucleation of Solids from Solution 137By James F. LutskoEffects of Protein Size on the High-Concentration/Low-Concentration Phase Transition 173By Patrick GrosfilsGeometric Constraints in the Self-Assembly of Mineral Dendrites and Platelets 193By John J. KozakWhat can Mesoscopic Level IN SITU Observations Teach us About Kinetics and Thermodynamics of Protein Crystallization? 223By Mike Sleutel, Dominique Maes, and Alexander Van DriesscheThe Ability of Silica to Induce Biomimetic Crystallization of Calcium Carbonate 277By Matthias Kellermeier, Emilio Melero-García, Werner Kunz, and Juan Manuel García-RuizAuthor Index 309Subject Index 325

Gregoire Nicolis studied engineering at the Technical University of Athens and received his doctorate in physics from the Université libre de Bruxelles, where he is currently Professor Emeritus at the Center for Nonlinear Phenomena and Complex Systems. His research focuses on the theory of irreversible processes, nonlinear phenomena, and complex systems.Dominique Maes is a Professor at the Institute of Molecular Biology and Biotechnology, Vrije Universiteit Brussel. Her research focuses on microgravity and the crystallization of proteins in space.Series EditorsStuart A. Rice received his master's and doctorate from Harvard University and was a junior fellow at Harvard for two years before joining the faculty of The University of Chicago in 1957, where he is currently the Frank P. Hixon Distinguished Service Professor Emeritus.Aaron R. Dinner received his bachelor's degree and doctorate from Harvard University, after which he conducted postdoctoral research at the University of Oxford and the University of California, Berkeley. He joined the faculty at The University of Chicago in 2003.

• Kinetics and Thermodynamics of Fluctuation-Induced Transitions in Multistable Systems 1By Gregoire Nicolis and Catherine NicolisDynamical Rare Event Simulation Techniques for Equilibrium and Nonequilibrium Systems 27By Titus S. Van ErpConfocal Depolarized Dynamic Light Scattering 61By M. Potenza, T. Sanvito, V. Degiorgio, and M. GiglioThe Two-Step Mechanism and The Solution-Crystal Spinodal for Nucleation of Crystals in Solution 79By Peter G. VekilovExperimental Studies of Two-Step Nucleation During Two-Dimensional Crystallization of Colloidal Particles with Short-Range Attraction 111By John R. Savage, Liquan Pei, and Anthony D. DinsmoreOn the Role of Metastable Intermediate States in the Homogeneous Nucleation of Solids from Solution 137By James F. LutskoEffects of Protein Size on the High-Concentration/Low-Concentration Phase Transition 173By Patrick GrosfilsGeometric Constraints in the Self-Assembly of Mineral Dendrites and Platelets 193By John J. KozakWhat can Mesoscopic Level IN SITU Observations Teach us About Kinetics and Thermodynamics of Protein Crystallization? 223By Mike Sleutel, Dominique Maes, and Alexander Van DriesscheThe Ability of Silica to Induce Biomimetic Crystallization of Calcium Carbonate 277By Matthias Kellermeier, Emilio Melero-García, Werner Kunz, and Juan Manuel García-RuizAuthor Index 309Subject Index 325

Gregoire Nicolis studied engineering at the Technical University of Athens and received his doctorate in physics from the Université libre de Bruxelles, where he is currently Professor Emeritus at the Center for Nonlinear Phenomena and Complex Systems. His research focuses on the theory of irreversible processes, nonlinear phenomena, and complex systems.Dominique Maes is a Professor at the Institute of Molecular Biology and Biotechnology, Vrije Universiteit Brussel. Her research focuses on microgravity and the crystallization of proteins in space.Series EditorsStuart A. Rice received his master's and doctorate from Harvard University and was a junior fellow at Harvard for two years before joining the faculty of The University of Chicago in 1957, where he is currently the Frank P. Hixon Distinguished Service Professor Emeritus.Aaron R. Dinner received his bachelor's degree and doctorate from Harvard University, after which he conducted postdoctoral research at the University of Oxford and the University of California, Berkeley. He joined the faculty at The University of Chicago in 2003.

• Kinetics and Thermodynamics of Fluctuation-Induced Transitions in Multistable Systems 1By Gregoire Nicolis and Catherine NicolisDynamical Rare Event Simulation Techniques for Equilibrium and Nonequilibrium Systems 27By Titus S. Van ErpConfocal Depolarized Dynamic Light Scattering 61By M. Potenza, T. Sanvito, V. Degiorgio, and M. GiglioThe Two-Step Mechanism and The Solution-Crystal Spinodal for Nucleation of Crystals in Solution 79By Peter G. VekilovExperimental Studies of Two-Step Nucleation During Two-Dimensional Crystallization of Colloidal Particles with Short-Range Attraction 111By John R. Savage, Liquan Pei, and Anthony D. DinsmoreOn the Role of Metastable Intermediate States in the Homogeneous Nucleation of Solids from Solution 137By James F. LutskoEffects of Protein Size on the High-Concentration/Low-Concentration Phase Transition 173By Patrick GrosfilsGeometric Constraints in the Self-Assembly of Mineral Dendrites and Platelets 193By John J. KozakWhat can Mesoscopic Level IN SITU Observations Teach us About Kinetics and Thermodynamics of Protein Crystallization? 223By Mike Sleutel, Dominique Maes, and Alexander Van DriesscheThe Ability of Silica to Induce Biomimetic Crystallization of Calcium Carbonate 277By Matthias Kellermeier, Emilio Melero-García, Werner Kunz, and Juan Manuel García-RuizAuthor Index 309Subject Index 325