The Editor David Bruyette, DVM, DACVIM (SAIM), is Chief Medical Officer at Anivive Lifesciences in Long Beach, California, USA.

“Overall, this is an up-to-date reference that focuses on foundational knowledge and covers the most common diseases seen in clinical small animal practice. It will be a solid addition to the reference library of any practice.” - JAVMA | DEC 15, 2020 | VOL 257 | NO. 12

• DedicationPrefaceList of ContributorsAbout the Companion WebsiteVolume ISection 1 Evaluation and Management of the Patient1 The Concept of One MedicineLonnie J. King2 Statistical Interpretation for PractitionersPhilip H. Kass3 Using Data For Clinical Decision MakingPhilip H. KassSection 2 Endocrine Disease4 Principles of EndocrinologyRobert Kemppainen5 NeuroendocrinologyMaya Lottati6 Feline AcromegalyDavid Bruyette7 Pituitary Dependent Hyperadrenocorticism in Dogs and CatsDavid Bruyette8 Polyuria and PolydipsiaJennifer L. Garcia9 Canine HypothyroidismDavid Bruyette10 Feline HyperthyroidismDavid Bruyette11 Hypoadrenocorticism in DogsPatty Lathan12 Diabetes Mellitus in Dogs and CatsJacquie S. Rand13 Hypoglycemia in Patients Without Diabetes Mellitus: Evaluation and ManagementRhett Nichols14 Canine Autoimmune Polyglandular SyndromesDeborah GrecoSection 3 Cardiovascular Disease15 Approach to the Patient with Suspected Cardiovascular DiseaseIngrid Ljungvall and Jens Häggström16 Imaging in Cardiovascular DiseaseValérie Chetboul17 ElectrocardiographyMarc S. Kraus and Anna R.M. Gelzer18 Pathophysiology of Heart FailureBarret J. Bulmer19 Management of Heart FailureSteven Rosenthal and Mark A. Oyama20 Ventricular ArrhythmiasAmara H. Estrada and Romain Pariaut21 Supraventricular ArrhythmiasRomain Pariaut and Amara H. Estrada22 Systemic HypertensionRebecca L. Stepien23 Pulmonary HypertensionHeidi B. Kellihan24 Congenital Heart DiseaseBrian A. Scansen25 Valvular Heart DiseaseMichele Borgarelli26 Canine Myocardial DiseaseM. Lynne O'Sullivan27 Feline Myocardial DiseaseVirginia Luis Fuentes28 Pericardial DiseaseAshley B. Saunders and Sonya G. GordonSection 4 Respiratory Disease29 A Respiratory Pattern-Based Approach to DyspneaChristopher G. Byers30 Feline Bronchial AsthmaChristine M. Serafin31 Canine Chronic BronchitisKevin Kumrow32 Pulmonary ThromboembolismRobert Goggs33 Surgical Approaches to Thoracic DiseaseRaegan Wells34 Pleural EffusionAshley Allen and Gareth BuckleySection 5 Critical Care Medicine35 Approach to the Patient in the Critical Care SettingSarah Allen36 Fluid TherapyTeresa Rieser37 Cardiopulmonary ResuscitationNathan Peterson38 Respiratory Monitoring in Critical CareMathew Mellema39 Acute Respiratory FailureMathew Mellema40 Mechanical VentilationKate Hopper and Mathew Mellema41 Approach to the Patient with ShockJames W. Barr42 Cardiogenic ShockNathan Peterson and James W. Barr43 Septic ShockJames W. Barr44 Disorders of Heat and ColdSarah Allen45 Acute PoisoningBen O'Kelley46 Medical Management of Trauma and BurnsNathan Peterson47 Venomous Snake BitesNathan PetersonSection 6 Gastrointestinal Disease48 Gastrointestinal ImagingSarah M. Stieger-Vanegas49 Gastrointestinal EndoscopyCraig Ruaux50 Diseases of the Oral Cavity and Salivary GlandsMaria Soltero-Reveira and Alexander Reiter51 Gastritis and Gastric Ulceration in Dogs and CatsKatie Tolbert52 Disorders of the EsophagusSilvia Funes and Craig Ruaux53 Motility Disorders of the Alimentary TractReito Neiger and Silke Salvati54 Exocrine Pancreatic Insufficiency in Dogs and CatsPanos Xenoulis55 Pancreatitis in the DogCaroline Mansfield56 Diagnosis and Management of Pancreatitis in the CatCraig Ruaux57 Rectoanal Diseases – Medical and Surgical ManagementCraig Ruaux58 Dysbiosis and the use of Pre-, Pro- and SynbioticsJan Suchodolski59 Diagnosis and Management of Chronic EnteropathiesKarin AllenspachSection 7 Diseases of the Liver, Gallbladder, and Bile Ducts60 Approach to the Patient with Liver DiseaseEmma O'Neill61 Imaging in Hepatobiliary DiseaseEsther Barrett62 Metabolic, Toxic and Neoplastic Diseases of the LiverJan Rothuizen63 Feline Inflammatory Liver DiseaseNicki Reed64 Canine Inflammatory Liver DiseaseNick Bexfield65 Cirrhosis and its ConsequencesKatherine Scott66 Portosystemic Shunts and Microvascular DysplasiaGeraldine Hunt67 Diseases of the Gallbladder and Extrahepatic Biliary DuctsBen HarrisSection 8 Neurologic Disease68 The Neurologic ExaminationAlexander DeLahunta69 Central Nervous System TraumaSimon R. Platt70 Seizures and Movement DisordersMichael Podell71 Disorders of the ForebrainSam N. Long72 Vestibular DiseaseTammy Stevenson73 Meningoencephalitis and MeningomyelitisChristopher L. Mariani74 Diseases of the Neuromuscular JunctionDavid Lipsitz75 MyopathiesMarguerite F. Knipe76 MyelopathyJoan R. Coates77 Neuro-OphthalmologyBradford J. HolmbergVolume IISection 9 Infectious DiseasePart 1 Diagnostic Considerations78 Epidemiology of Infectious DiseasePeggy L. Schmidt79 Laboratory Diagnosis of Infectious DiseaseLaia Solano-Gallego and Gad BanethPart 2 Select Infectious Diseases and Disease Agents80 Canine DistemperDavid Bruyette81 Canine Herpes VirusYvonne Dreschler82 Canine Viral EnteritisMargaret C. Barr83 Viral PapillomatosisMargaret C. Barr84 Canine Influenza VirusEllen Collisson85 Feline ParvovirusMargaret C. Barr86 Feline CoronavirusYvonne Dreschler87 Feline Leukemia VirusDavid Bruyette88 Feline Immunodeficency Virus (FIV)Tom Phillips89 Feline Viral Upper Respiratory DiseaseYvonne Dreschler90 Rabies in Dogs and CatsEmily Beeler and Karen Ehnert91 West Nile VirusTracey McNamara92 Ebola VirusLinda Kidd93 Ehrlichia and AnaplasmaPedro P. Vissotto de Paiva Diniz94 Salmon Poisoning DiseasePedro P. Vissotto de Paiva Diniz95 Wolbachia pipientis InfectionPedro P. Vissotto de Paiva Diniz96 BartonellosisPedro P. Vissotto de Paiva Diniz97 Hemotropic MycoplasmaSéverine Tasker98 Non-Hemotropic Mycoplasma, Ureaplasma and L-form BacteriaJoachim Spergser99 Spotted Fever and Typhus Group RickettsiaLinda Kidd100 Lyme BorreliosisMerryl P. Littman101 LeptospirosisKatharine F. Lunn102 YersiniosisMaria Grazia Pennisi103 TularemiaLinda Kidd104 Q FeverLinda Kidd105 BrucellosisErin E. Runcan106 Tetanus and BotulismAndrea Fischer107 AnthraxWayne E. Wingfield and Jerry J. Upp108 Actinomyces, Nocardiosis, and Mycobacterial InfectionsJoanna Whitney and Vanessa R. Barrs109 Fungal InfectionsJane E. Sykes110 Protozoal and Protozoa-Like InfectionsGad Baneth and Laia Solano-Gallego111 CoccidiaChris Adolph112 Surgical, Traumatic and Bite Wound InfectionsLaura L. Nelson113 Canine Infectious Respiratory Disease ComplexJonathan DearPart 3 Therapeutic Considerations114 Antimicrobial Therapy in Dogs and CatsKatrina R. Viviano115 Antifungal TherapyDaniel S. FoyPart 4 Special Topics116 Nosocomial and Multi-Drug Resistant InfectionsJason W. Stull and Scott Weese117 Management of Infectious Disease in Kennels and Multi-Cat Environments: Creating a Culture of ComplianceFrank BossongSection 10 Renal and Genitourinary Disease118 Disorders of Sodium and Water HomeostasisJulien Guillaumin and Stephen DiBartola119 Disorders of Magnesium and PhosphorusRosanne Jepson120 Acute Kidney InjuryAdam E. Eatroff121 Glomerular DiseaseShelly L. Vaden122 Obstructive UropathyEdward Cooper and Brian A. Scansen123 Urolithiasis in Small AnimalsAlice Defarges, Michelle Evason, Marilyn Dunn, and Allyson Berent124 Prostatic DiseasesSerge Chalhoub125 Management of Chronic Renal DiseaseJessica Quimby126 The Role of DialysisAdam E. Eatroff127 Micturition and Associated DisordersJulie K. Byron128 Urinary Tract InfectionsNicole SmeeSection 11 Oncologic Disease 129 Approach to the Cancer PatientLisa DiBernardi130 Biology of Cancer and Cancer GeneticsMary-Keara Boss131 Endocrine Manifestations of Cancer: Ectopic Hormone ProductionCory Brown132 Paraneoplastic SyndromesCory Brown133 Lymphoid Leukemias, Myeloid Neoplasia and Myelodysplastic SyndromeAngela R. Kozicki134 LymphomasKristine Elaine Burgess135 Plasma Cell DisordersOrna Kristal136 Central Nervous System Tumors in Dogs and CatsDavid Ruslander137 Cancer of the Nose and MouthLauren Askin Quarterman138 Tumors of the Eye and Ocular AdnexaErin M. Scott and Paul E. Miller139 Cancer of the HeartNick A. Schroeder and Lisa DiBernardi140 Cancer of the Airway and LungJoanne L. Intile141 Cancer of the Esophagus and StomachAvenelle I. Turner142 Cancer of the Small and Large IntestineEdwin Brodsky143 Exocrine Pancreatic CancerAvenelle I. Turner144 Pancreatic Endocrine TumorsKaren Eiler145 Liver and Biliary Tract TumorsAmanda K. Elpiner146 Tumors of the Urinary TractPedro A. Boria147 Tumors of the Male Reproductive SystemTrina Hazzah148 Gynecologic CancersTrina Hazzah149 Mammary CancerJulie Bulman-Fleming150 Tumors of Bone and JointStephanie L. Shaver, William T. N. Culp, and Robert B. Rebhun151 Soft Tissue SarcomasLauren Askin Quarterman152 HemangiosarcomaChristine B. Oakley and John D. Chretin153 MelanomaPhilip J. Bergman154 Non-melanoma Skin CancersBarbara E. Kitchell155 Mast Cell NeoplasiaZachary M. Wright156 Apheresis in Companion AnimalsSteve SuterSection 12 Skin and Ear Diseases157 Approach to the Patient with Dermatologic DiseaseLisa V. Reiter158 Principles of Therapy of Skin DiseasesSandra N. Koch159 Atopic DermatitisAlison Diesel160 Allergic Skin DiseasesPatrick Hensel161 Cutaneous Adverse Food ReactionsRalf S. Mueller162 Autoimmune and Immune-mediated Skin DiseasesNicole A. Heinrich163 Approach to AlopeciaLinda A. Frank164 Sterile Papular and Nodular Skin DiseasesSandra Diaz165 Parasitic Skin DiseasesElizabeth E. Toops166 Bacterial PyodermasJennifer R. Schissler167 OtitisSue Paterson168 Cutaneous Manifestations of Systemic DiseaseKinga Gortel169 Superficial Necrolytic DermatitisMitchell D. Song170 Miscellaneous Skin DiseasesLisa V. Reiter and Sheila M. F. TorresSection 13 Diseases of Bone and Joint171 Skeletal Development and HomeostasisMatthew J. Allen and Gert J. Breur172 Metabolic Bone DiseasesKeren E. Dittmer173 Osteoarthritis in Small AnimalsSteven A. Martinez174 Developmental Orthopedic DiseasesGert J. Breur, N. E. Lambrechts, and H. A. Towle MillardSection 14 Social and Ethical Issues in Veterinary Medicine175 Canine and Feline End of Life CareRobin DowningSection 15 Preventative Care176 Role of ImmunizationMelissa Kennedy177 Behavior Triage for Internists and the General PractitionerKaren SuedaSection 16 Laboratory SupportIndex