About the EditorsMary E. Lynch, MD, FRCPC, Founder (Pain Medicine) is a Clinician, Researcher and Entrepreneur who has dedicated her career to improving the lives of people living with chronic pain conditions. She is a Professor of Anesthesia, Pain Management and Perioperative Medicine, Psychiatry and Pharmacology at Dalhousie University, Nova Scotia and a Founder of Pain Medicine at the Royal College Physicians and Surgeons, Canada. Kenneth D. Craig, OC, PhD, FCAHS is a Clinician/Scientist focused upon psychosocial features of acute and chronic pain published in over 250 peer-reviewed papers, edited chapters in professional and scientific volumes, and books. He is Professor Emeritus of Psychology at the University of British Columbia. Philip H. Peng, MBBS, FRCPC, Founder (Pain Medicine) is a Clinical Professor in Anesthesiology and Pain Medicine at the University of Toronto. He is a leader, researcher and educator in pain medicine as well as a pioneer in the application of ultrasound for pain medicine. His innovative research led to new procedures in pain intervention. He received numerous international and national awards and was granted the Founder of Pain Medicine at the Royal College Physicians and Surgeons, Canada. He has edited 8 books and published 240 peer-reviewed publications and book chapters.

• Foreword/ prefaceForeword to first editionPart 1: Basic Understanding of Pain Medicine1 The challenge of pain: a multidimensional phenomenon2 Epidemiology and economics of recurrent and chronic non-cancer pain3 Basic mechanisms and pathophysiology4 Psychosocial Aspects of Pain5 Identification of risk and protective factors in the transition from acute to chronic post-surgical pain6 Placebo/nocebo: a two-sided coin in the clinician’s hand7 Knowledge transfer to patients experiencing pain and poor sleep and sleep disorderPart 2: Assessment of Pain8 Clinical assessment in adult patients9 Measurement and assessment of pain in pediatric patients10 Laboratory investigations, imaging, and neurological assessment in pain management11 Psychological assessment of persons with chronic painPart 3: Management12 Introduction to management13 Managing chronic pain in primary care14 Medical nutrition therapy for chronic pain management15 Physical therapy and rehabilitationPart 4: Pharmacotherapy16 Antidepressant analgesics in the management of chronic pain17 Anticonvulsants in the management of chronic pain18 Opioids19 Topical analgesics20 Cannabinoids and other agents21 Combined pharmacotherapy for chronic pain managementPart 5: Interventional22 Diagnostic and therapeutic blocks23 Neuromodulation therapy24 Neurosurgical management of painPart 6: Psychological25 Pain self-management: theory and process for clinicians26 Psychological interventions: a focus on cognitive behavioral therapy27 Pain catastrophizing and fear of movement: detection and interventionPart 7: Complementary Therapies28 Complementary and integrative health approaches for pain reliefPart 8: Specific Clinical States29 Low Back Pain30 Fibromyalgia syndrome and myofascial pain syndromes31 Clinical pain management in the rheumatic diseases32 Headache33 Orofacial Pain34 Visceral Pain35 Pelvic and Urogenital Pain36 Neuropathic Pain37 Complex Regional Pain Syndrome38 Cancer Pain39 Pain and AddictionPart 9: Special Populations40 Pain in older adults: a brief clinical41 Pain in Children42 Pain in individuals with intellectual disabilities43 Pain and Psychiatric Illness44 Basic principles in acute and perioperative pain in patients with opiod toleranceSubject index

About the EditorsMary E. Lynch, MD, FRCPC, Founder (Pain Medicine) is a Clinician, Researcher and Entrepreneur who has dedicated her career to improving the lives of people living with chronic pain conditions. She is a Professor of Anesthesia, Pain Management and Perioperative Medicine, Psychiatry and Pharmacology at Dalhousie University, Nova Scotia and a Founder of Pain Medicine at the Royal College Physicians and Surgeons, Canada. Kenneth D. Craig, OC, PhD, FCAHS is a Clinician/Scientist focused upon psychosocial features of acute and chronic pain published in over 250 peer-reviewed papers, edited chapters in professional and scientific volumes, and books. He is Professor Emeritus of Psychology at the University of British Columbia. Philip H. Peng, MBBS, FRCPC, Founder (Pain Medicine) is a Clinical Professor in Anesthesiology and Pain Medicine at the University of Toronto. He is a leader, researcher and educator in pain medicine as well as a pioneer in the application of ultrasound for pain medicine. His innovative research led to new procedures in pain intervention. He received numerous international and national awards and was granted the Founder of Pain Medicine at the Royal College Physicians and Surgeons, Canada. He has edited 8 books and published 240 peer-reviewed publications and book chapters.

• Foreword/ prefaceForeword to first editionPart 1: Basic Understanding of Pain Medicine1 The challenge of pain: a multidimensional phenomenon2 Epidemiology and economics of recurrent and chronic non-cancer pain3 Basic mechanisms and pathophysiology4 Psychosocial Aspects of Pain5 Identification of risk and protective factors in the transition from acute to chronic post-surgical pain6 Placebo/nocebo: a two-sided coin in the clinician’s hand7 Knowledge transfer to patients experiencing pain and poor sleep and sleep disorderPart 2: Assessment of Pain8 Clinical assessment in adult patients9 Measurement and assessment of pain in pediatric patients10 Laboratory investigations, imaging, and neurological assessment in pain management11 Psychological assessment of persons with chronic painPart 3: Management12 Introduction to management13 Managing chronic pain in primary care14 Medical nutrition therapy for chronic pain management15 Physical therapy and rehabilitationPart 4: Pharmacotherapy16 Antidepressant analgesics in the management of chronic pain17 Anticonvulsants in the management of chronic pain18 Opioids19 Topical analgesics20 Cannabinoids and other agents21 Combined pharmacotherapy for chronic pain managementPart 5: Interventional22 Diagnostic and therapeutic blocks23 Neuromodulation therapy24 Neurosurgical management of painPart 6: Psychological25 Pain self-management: theory and process for clinicians26 Psychological interventions: a focus on cognitive behavioral therapy27 Pain catastrophizing and fear of movement: detection and interventionPart 7: Complementary Therapies28 Complementary and integrative health approaches for pain reliefPart 8: Specific Clinical States29 Low Back Pain30 Fibromyalgia syndrome and myofascial pain syndromes31 Clinical pain management in the rheumatic diseases32 Headache33 Orofacial Pain34 Visceral Pain35 Pelvic and Urogenital Pain36 Neuropathic Pain37 Complex Regional Pain Syndrome38 Cancer Pain39 Pain and AddictionPart 9: Special Populations40 Pain in older adults: a brief clinical41 Pain in Children42 Pain in individuals with intellectual disabilities43 Pain and Psychiatric Illness44 Basic principles in acute and perioperative pain in patients with opiod toleranceSubject index

About the EditorsMary E. Lynch, MD, FRCPC, Founder (Pain Medicine) is a Clinician, Researcher and Entrepreneur who has dedicated her career to improving the lives of people living with chronic pain conditions. She is a Professor of Anesthesia, Pain Management and Perioperative Medicine, Psychiatry and Pharmacology at Dalhousie University, Nova Scotia and a Founder of Pain Medicine at the Royal College Physicians and Surgeons, Canada. Kenneth D. Craig, OC, PhD, FCAHS is a Clinician/Scientist focused upon psychosocial features of acute and chronic pain published in over 250 peer-reviewed papers, edited chapters in professional and scientific volumes, and books. He is Professor Emeritus of Psychology at the University of British Columbia. Philip H. Peng, MBBS, FRCPC, Founder (Pain Medicine) is a Clinical Professor in Anesthesiology and Pain Medicine at the University of Toronto. He is a leader, researcher and educator in pain medicine as well as a pioneer in the application of ultrasound for pain medicine. His innovative research led to new procedures in pain intervention. He received numerous international and national awards and was granted the Founder of Pain Medicine at the Royal College Physicians and Surgeons, Canada. He has edited 8 books and published 240 peer-reviewed publications and book chapters.

• Foreword/ prefaceForeword to first editionPart 1: Basic Understanding of Pain Medicine1 The challenge of pain: a multidimensional phenomenon2 Epidemiology and economics of recurrent and chronic non-cancer pain3 Basic mechanisms and pathophysiology4 Psychosocial Aspects of Pain5 Identification of risk and protective factors in the transition from acute to chronic post-surgical pain6 Placebo/nocebo: a two-sided coin in the clinician’s hand7 Knowledge transfer to patients experiencing pain and poor sleep and sleep disorderPart 2: Assessment of Pain8 Clinical assessment in adult patients9 Measurement and assessment of pain in pediatric patients10 Laboratory investigations, imaging, and neurological assessment in pain management11 Psychological assessment of persons with chronic painPart 3: Management12 Introduction to management13 Managing chronic pain in primary care14 Medical nutrition therapy for chronic pain management15 Physical therapy and rehabilitationPart 4: Pharmacotherapy16 Antidepressant analgesics in the management of chronic pain17 Anticonvulsants in the management of chronic pain18 Opioids19 Topical analgesics20 Cannabinoids and other agents21 Combined pharmacotherapy for chronic pain managementPart 5: Interventional22 Diagnostic and therapeutic blocks23 Neuromodulation therapy24 Neurosurgical management of painPart 6: Psychological25 Pain self-management: theory and process for clinicians26 Psychological interventions: a focus on cognitive behavioral therapy27 Pain catastrophizing and fear of movement: detection and interventionPart 7: Complementary Therapies28 Complementary and integrative health approaches for pain reliefPart 8: Specific Clinical States29 Low Back Pain30 Fibromyalgia syndrome and myofascial pain syndromes31 Clinical pain management in the rheumatic diseases32 Headache33 Orofacial Pain34 Visceral Pain35 Pelvic and Urogenital Pain36 Neuropathic Pain37 Complex Regional Pain Syndrome38 Cancer Pain39 Pain and AddictionPart 9: Special Populations40 Pain in older adults: a brief clinical41 Pain in Children42 Pain in individuals with intellectual disabilities43 Pain and Psychiatric Illness44 Basic principles in acute and perioperative pain in patients with opiod toleranceSubject index