Rossi's Principles of Transfusion Medicine

Toby L. Simon, MD is Senior Medical Director for Plasma and Plasma Safety with CSL Plasma and in Research and Development for the parent company CSL Behring, He is past-president of AABB and America’s Blood Centers. He has been on the faculty of University of New Mexico School of Medicine (currently clinical faculty), Medical Director of TriCore Reference Laboratories and industry representative to the FDA Blood Products Advisory Committee. Eric A. Gehrie, MD is a clinical pathologist who specializes in blood banking/transfusion medicine. He is currently the Executive Physician Director over Direct Patient Care and Emerging Cell and Gene Therapy Solutions at the American Red Cross. He has previously been on the faculty of both Yale and Johns Hopkins University Schools of Medicine. He is a member of the editorial board of Transfusion. Jeffrey McCullough, MD is Professor Emeritus at the University of Minnesota Medical School with experience in both hospital transfusion services and blood centers. He was the editor of Transfusion for 15 years and the founding president of the US National Marrow Donor Program. He is currently an international advisor in transfusion medicine. He is past-president of the American Board of Pathology. John D. Roback, MD, PhD is a Professor in the Department of Pathology and Laboratory Medicine at Emory University. His appointments include Medical Director of Emory Medical Laboratories, Emory/Children’s Laboratory for Innovative Assay Development, and the Center for Transfusion and Cellular Therapies. He is also Executive Vice-Chair of Clinical Operations. He is a former editor of the AABB Technical Manual. Edward L. Snyder, MD, FACP is Professor of Laboratory Medicine and Attending Physician in the Transfusion and Tissue Services at Yale Medical School/Yale New Haven Hospital. He is also the blood bank director at Bridgeport Hospital. He is past chair of the BeTheMatch Board of Directors and is a past-president of AABB. He is an associate editor of Transfusion and past-recipient of Emily Cooley, Morton Grove-Rasmussen and presidential awards from AABB.

• ContributorsPrefaceList of abbreviationsSection I: Transfusion medicine from ancient times to the current pandemic Chapter 1. Transfusion in the new millennium – Ennio C. Rossi and Toby L. SimonChapter 2. Disaster and the blood community (including COVID-19)-Ruth Sylvester and Louis M. KatzChapter 3. Responding to the Regulatory Challenges during Emergencies and Epidemics- Peter Mark                                                     Section II: Blood donationChapter 4 Recruitment and screening of donors and the collection of blood—Susan Rossmann, Mary Townsend and Toby L. SimonChapter 5 Blood donor testing—Jed B. Gorlin and Nancy Van BurenChapter 6 Acute adverse reactions after blood donation– Anne F. EderChapter 7 Chronic effects of blood and plasma donation—Bryan Spencer and T. SimonChapter 8 Global perspective: ensuring blood and blood product safety and availability through regulation and certification-Eva D. QuinleySection III: Blood groups and pretransfusion testingChapter 9 Carbohydrate blood groups- Laura CoolingChapter 10 Rh and LW blood group antigens- Connie M. Westhoff, Don L. Siegel, and Aline FlochChapter 11 Other protein blood groups- Jill Storry and Jennifer Ricci HagmanChapter 12 Molecular and routine compatibility testing–Connie WesthoffSection IV: Blood components Part A. Red cells Chapter 13 Red blood cell production and kinetics—Mark J. Koury and Lionel BlancChapter 14 Red cell metabolism, preservation and oxygen delivery—John Hess and Angelo D’Alessandro Part B: PlateletsChapter 15 Platelet production and kinetics- Christopher A. Tormey, Henry M. Rinder, and Thomas C. BinnsChapter 16 Platelet immunology and alloimmunization- Cheryl L. Maier and Seema R. Patel and H. Clifford Sullivan Chapter 17 Preparation, preservation, and storage of platelet concentrates- Moritz Stolla and Valery J. Li and Johnathan P. Mack  Part C: White cellsChapter 18 Neutrophil production and kinetics: neutropenia and neutrophilia- Lawrence Rice and Eric Salazar  Chapter 19 Granulocyte collection and transfusion- Jeffrey McCullough, Corrinne Goldberg and Jenny Petkova Part D: PlasmaChapter 20 Composition of plasma – Peter HellsternChapter 21 Plasma and cryoprecipitate for transfusion including SD plasma- Simon Stanworth and Toruma Apelseth Chapter 22 The purification of plasma proteins for therapeutic use- Nathan Brinkman, Karl McCann, and Barry Gooch  Chapter 23  Immunoglobulins Products- Melvin BergerSection V: ApheresisChapter 24 Basic principles of apheresis and the collection of blood components by apheresis- Jeffrey L. Winters and Edwin A. BurgstalerChapter 25 Therapeutic apheresis: Plasma processing – Patricia A.R. Brunker and Monica B. Pagano Chapter 26  Therapeutic phlebotomy and specialized hemapheresis- Patricia Brunker and Jeffey BaileySection VI: Blood transfusionChapter 27 Patient blood management- Darrell J. Triulzi and Jansen N. Seheult and Mark H. Yazer and Jonathan H. WatersChapter 28 Clinical and technical aspects of blood administration – Edward S. Lee, Debra L. Mraz, and Edward L. SnyderChapter 29 Anemia and RBC transfusion- Jeff CarsonChapter 30 Sickle cell disease, thalassemia, and hereditary hemolytic anemias-Ross M. Fasano, Emily Riehm Meier and Satheesh ChonatChapter 31 Autoimmune hemolytic anemias and paroxysmal nocturnal hemoglobinuria-Christopher A. Tormey and Alexa J. Siddon Chapter 32 Hemolytic disease of the fetus and newborn- Megan Delaney, Wen Lun, Jennifer Webb Chapter 33 Obstetric transfusion practice- RobackChapter 34 Transfusion in Infants and Children-Jeanne E. Hendrickson and Cassandra D. JosephsonChapter 35 Thrombocytopenia and platelet transfusion-Michael F. Murphy, Lise J Estcourt and Simon J. Stanworth Chapter 36 Immune mediated Thombocytopenia- Theodore Warkentin, Donald Arnold, Ishac Nazi, and James W. Smith Chapter 37 Coagulation Concentrates for Inherited Bleeding Disorders—Robert F. Sidonio and Gary M. WoodsChapter 38 Coagulation factor concentrates and pharmacologic therapies for acquired bleeding disorders- Ravi Sarode and Natalie BavliChapter 39 Perioperative transfusion practice- James R. Stubbs, Allan Klompas, and Leanne ThaljiChapter 40 Transfusion therapy in the care of trauma and burn patients- John R. Hess, Eileen M. Bulger, Benjamin Huebner, and Samuel Mandell Chapter 41 Transfusion support for the oncology patient- Kristin M. Stendahl, Wade L. Schulz, Edward L. SnyderChapter 42 Pathogen reduction of blood components- Snyder and McCullough                  Section VII: Adverse sequelae of transfusionChapter 43 Hemovigilance: weighing transfusion risks and benefits- Scott KopesellChapter 44 Transfusion transmitted virus infections-Erhard SeifriedChapter 45 Transfusion transmission of parasites and prions - Bryan Spencer and Paula SaaChapter 46 Bacterial Contamination of Blood Components- Evan M. Bloch, Richard J. Benjamin and Sandra Ramirez Chapter 47 Hemolytic transfusion reactions- Celina Montemayor Garcia and Sandhya R. PanchChapter 48 Febrile, allergic, and nonimmune transfusion reactions- Emmanuel A. Fadeyi and Gregory J. PomperChapter 49 Transfusion-related lung injury- Ulrich Sachs and Johnathan P. WallisChapter 50 Transfusion-associated graft-versus-host disease- Eric A. Gehrie and Courtney E. LawrenceChapter 51 Transfusion-associated iron overload- Sujit Sheth Section VIII: Cellular and tissue transplant technologiesChapter 52 Hematopoetic growth factors and Cytokines-David KuterChapter 53 Hematopoetic stems cells and transplantation- Garrett S. BoothChapter 54 HLA antigens, alleles, and antibodies—Harold Clifford Sullivan, Robert A. Bray, Howard M. Gebel and Scott M. KrummeyChapter 55 Car-T cells and other cellular immunotherapies- Don Siegel and Andrew FesnakChapter 56 Gene therapy applications to transfusion medicine-Diane S. Krause, Seena Tabibi, Emanuela M. Bruscia and Eric A. GehrieChapter 57 Tissue engineering and regenerative medicine-Julie G. AllicksonChapter 58 Human Tissue Allografts: Following the Path from Donor to Recipient - Matthew J. Kuehnert and Cassandra D. Josephson     Index