Doctor Doom has conquered the world, and that spells nothing but trouble for the Fantastic Four!

The impossible has happened! Doctor Doom has taken over the world! And the Fantastic Four are not going to let that stand. As Reed locks himself in his lab, trying to solve the Problem of Doom, Ben treats Sue to a trip to NYC with their mutual friend She-Hulk to help get her mind off things. But when Ben, Sue and Jen find themselves on the wrong side of mob justice, they face a choice — and it’s one they will not be able to take back! And when the Thing suffers a terrible (and very public) defeat at Doom’s hands, he’s left lost, adrift and more vulnerable than he has been in years. Just as Ben begins to recover, the FF learn they’re losing their powers — at the one time they need them the most desperately! If they can’t reverse the effect, their powers may be lost forever — and Doom will be unstoppable! All that plus Namor, the Sub-Mariner!

COLLECTING: Fantastic Four (2022) 29-33, Giant-Size Fantastic Four (2024) 1