Androgens and Androgen Receptor

Mechanisms, Functions, and Clini Applications

Inbunden, Engelska, 2002

1 637 kr

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Beskrivning

This is a comprehensive analysis of androgens and androgen receptor, including discussions of the basic mechanisms of androgen-androgen receptor actions, their roles in the androgen-related diseases, and their potential clinical applications. This book covers key topics including: the discovery and cloning of the androgen receptor; androgen receptor co regulators; androgen related genes and their consensus DNA response elements and the basic mechanism of action including functional analyses, cellular localization and phosphorylation studies. It explores the cross-talk to other signal transduction systems and the recent connections of androgens to women's diseases, such as osteoporosis and ovarian cancer. This book could be of interest to students, basic scientists, and clinicians as both a study guide and reference of research in the androgen field. It could also be used as an advanced level text in endocrinology, urology, OBGYN, or oncology.

Produktinformation

Utgivningsdatum:2002-10-31
Mått:155 x 235 x 33 mm
Vikt:939 g
Format:Inbunden
Språk:Engelska
Antal sidor:503
Upplaga:2002
Förlag:Kluwer Academic Publishers
ISBN:9781402071881

Utforska kategorier

Fysiologi inom Medicin
Veterinärmedicin inom Medicin

Mer om författaren

Chawnshang Chang, Ph.D., is the George Hoyt Whipple Distinguished Professor at the University of Rochester.

Innehållsförteckning

1. Androgen Biosynthesis and Degradation.- 2. Structural and Functional Analysis of the Androgen Receptor.- 3. Signal Transduction Pathways Modulate Androgen Receptor Transcriptional Activity.- 4. Androgen Receptor Interacting Proteins Co-Activators and Co-Repressors.- 5. Nongenomic Androgen Action.- 6. The Role of 5?-Reductase in Prostate Disease and Male Pattern Baldness.- 7. Natural Products and Environmental Androgens/Antiandrogens.- 8. Androgens in Prostate Cancer and Benign Prostatic Hypoplasia.- 9. The Expanded Poly-Q Length Within AR and AR Coregulator A1B1 And Their Clinical Implications.- 10. Androgen Receptor with Expanded Poly-Q Length in SBMA (Kennedy Disease).- 11. Androgen Insensivity Syndrome (Testicular Feminization).- 12. Androgens in Immunology and Autoimmune Diseases.- 13. Androgens in Penile Development, Penile Erection and Erectile Dysfunction.- 14. Androgens and the Androgen Receptor in Male Sex Development and Fertility.- 15. Androgens and Brain Function: Behavioral Perspectives.- 16. Androgens, Skeletal Homeostasis, and Osteoporosis.- 17. Androgens and Coronary Artery Disease.- 18. Androgen Therapy in Nonendocrine Illnesses.- 19. Androgens and Androgen Receptor in Dermatology.- 20. Androgen Deficiency and Abnormality in Women.