Paul J. Wang, MDCardiovascular Medicine, Department of MedicineStanford University Medical CenterStanford, CA, USA Henry H. Hsia, MDCardiovascular Medicine, Department of MedicineStanford University Medical CenterStanford, CA, USAAmin Al-Ahmad, MDCardiovascular Medicine, Department of MedicineStanford University Medical CenterStanford, CA, USAPaul C. Zei, MDCardiovascular Medicine, Department of MedicineStanford University Medical CenterStanford, CA, USA

“This leading text serves as a guide to this area of increasing clinical importance. As the most comprehensive book on this topic, it will serve as the text that this readership will turn to first. This comprehensive book provides detailed insight into the mechanisms and treatment of ventricular arrhythmia. This is a well designed primer on the intricate mechanisms of ventricular arrhythmias and on the modalities available for diagnosis and treatment of patients. Written by eminent authors with experience in both the clinic and the laboratory, it provides a valuable synthesis of current perspectives on state-of-the-art in the field.” (Doody's Book Reviews, October 2008)

• List of contributors viiForeword xiHein J. WellensPart 1 Mechanisms of VT1 The role of spatial dispersion of repolarization and intramural reentry in inherited and acquired sudden cardiac death syndromes 1Charles Antzelevitch2 Mechanisms of ventricular tachycardia: underlying pathological and physiological abnormalities 18Jacques MT de Bakker Harold VM van RijenPart 2 Etiologies and syndromes3 Time-dependent gender differences in the clinical course of patients with the congenital long-QT syndrome 28Ilan Goldenberg Arthur J. Moss Wojciech Zareba4 Genetics of ventricular arrhythmias 37Zian H. Tseng Jeffrey Olgin5 Arrhythmogenic right ventricular dysplasia/cardiomyopathy 51Rahul Jain Hugh Calkins6 Risk stratification and the implantable defibrillator for the prevention of sudden death in hypertrophic cardiomyopathy 64Barry J. MaronPart 3 Catheter and surgical ablation7 Mapping and ablation of ventricular tachycardia after myocardial infarction 76William G. Stevenson Usha Tedrow8 Mapping and ablation of ventricular tachycardia in nonischemic cardiomyopathy 89Henry H. Hsia Pirooz S. Mofrad9 Mapping to define scars and isthmuses: a new paradigm for guiding ventricular tachycardia ablation 101Kyoko Soejima10 Ablation of idiopathic ventricular tachycardias 112Nitish Badhwar Melvin M. Scheinman11 Ablation of ventricular fibrillation 128Karen P. Phillips J. David Burkhardt Robert A. Schweikert Walid I. Saliba Andrea Natale12 Ablation of ventricular tachycardia in congenital heart disease 141George F. Van Hare13 Role of imaging techniques in catheter ablation of ventricular tachycardia 150Mathew D. Hutchinson David J. Callans14 Epicardial ablation of ventricular tachycardia 164Mauricio Scanavacca Eduardo Sosa15 Role of catheter control systems in ablation of ventricular tachycardia 178Marco Perez Amin Al-Ahmad16 Current surgical techniques for ischemic ventricular tachycardia 190Robert J. Moraca Marci S. Bailey Ralph J. Damiano JrPart 4 Epidemiology risk stratificationand pharmacological therapy for ventricular tachycardia and sudden death17 Epidemiology and etiologies of sudden cardiac death 198Keane K. Lee Amin Al-Ahmad Paul J.Wang Robert J. Myerburg18 Non-invasive tests for risk stratification in ischemic and non-ischemic cardiomyopathy 213J. Thomas Bigger Mark C. Haigney Robert E. Kleiger19 Risk stratification: where we are and where do we go from here 240Jeffrey J. Goldberger20 Pharmacological management of ventricular arrhythmias 247Kevin J. Makati Munther Homoud Mark S. Link Jonathan Weinstock N.A. Mark Estes IIIPart 5 Ventricular fibrillation and defibrillation21 The mechanisms of ventricular fibrillation 267Lan S. Chen Peng-Sheng Chen Moshe S. Swissa22 Mechanisms of defibrillation 277Derek J. Dosdall Jian Huang Raymond E. Ideker23 Automatic external defibrillation and public access defibrillator response 289Paul J. Wang Amin Al-Ahmad Robert J. Myerburg24 Advances in cardiopulmonary rescuscitation 298Anurag Gupta Amin Al-Ahmad25 Advances in implantable defibrillator therapy and technologies 312Paul J. Wang Amin Al-Ahmad Henry H. Hsia Paul C. Zei26 ICD lead extraction: when why and how? 327Bruce L. Wilkoff Oussama WazniIndex 335