Clinical Electrophysiology

Peter W. Kaplan, MD, FRCP, Professor of Neurology, John Hopkins Hospital, Baltimore, MD Thien Nguyen, MD, PhD, Assistant Professor of Neurology, John Hopkins Hospital, Baltimore, MD

"It would be a useful reference in that setting because it presents classic examples of entities that clinicians are most likely to encounter in an inpatient setting." (Doody's, 30 September 2011) "In conclusion, Kaplan and Nguyen have bravely created a book "in the middle", between a detailed electrophysiology textbook (a "comprehensive tome"), a case book, and an atlas; this book is worth reading, but probably not during rounds." (The Lancet Neurology, 1 April 2011)

• Preface. Introduction.Part 1: Central Nervous System Disorders.Section A: Altered consciousness: confusion, delirium and unresponsiveness; agitation hallucination and abnormal behavior.1. Diffuse and frontal fast activity—beta.2. Diffuse slow activity—theta.3. Diffuse slow activity—delta.4. Frontal intermittent rhythmic delta activity.5. Occipital intermittent rhythmic delta activity.6. Triphasic waves.7. Low-voltage fast record without dominant alpha frequencies.8. Alpha coma.9. Spindle coma.10. Low-voltage suppressed pattern.11. Burst/suppression.12. Diffuse slowing—toxic encephalopathy—baclofen.13. Diffuse slowing—metabolic encephalopathy—lithium.14. Diffuse slowing—metabolic encephalopathy—hypoglycemia.15. Diffuse slowing—limbic encephalopathy.16. Focal arrhythmic (polymorphic) delta activity.Section B: Periodic patterns of epileptiform discharges, or seizures.17. Pseudoperiodic lateralized epileptiform discharges.18. Bilateral independent pseudoperiodic epileptiform discharges.19. Generalized periodic epileptiform discharges.Part 2: Seizures.Section A: The Diagnosis of confusional events due to seizures.20. Frontal lobe simple and complex partial seizures.21. Temporal lobe simple and complex partial seizures.22. Parietal lobe simple partial seizures.23. Occipital lobe simple partial seizures.Section B: Status epilepticus.24. Complex partial status epilepticus—frontal.25. Complex partial status epilepticus—temporal.26. Simple partial status epilepticus—parietal.27. Simple partial status epilepticu—occipital.28. Generalized nonconvulsive status epilepticus.Part 3: Conditions of Prolonged Unresponsiveness.Section A: Locked-in syndrome, minimally conscious state, vegetative state, and coma: disorders of consciousness and responsiveness.29. Clinical definitions of impaired responsiveness.Section B: Prolonged unresponsive states.30. Locked-in syndrome—brainstem hemorrhage.31. Vegetative state—postanoxia.32. Minimally conscious state—after large, multifocal strokes.33. Catatonia—psychogenic unresponsiveness/conversion disorder.34. Somatosensory evoked potential Prognosis in anoxic coma.35. Somatosensory evoked potential Prognosis in head trauma.Section C: Evoked Potentials in Consultative Neurology.36. Somatosensory evoked potentials in midbrain lesion—absent cortical responses.37. Somatosensory evoked potentials in diffuse cortical anoxic injury—absent cortical and subcortical responses.38. Somatosensory evoked potentials in prolonged cardiac arrest—absence of all waves above the brachial plexus.39. Somatosensory evoked potentials after prolonged cardiac arrest—absence of all responses except cervical N9.40. Somatosensory evoked potentials—median and tibial after traumatic spinal cord injury.41. Visual evoked potentials in worsening vision.42. Brainstem auditory evoked potentials—in worsening hearing.Part 4: Peripheral Nervous System Disease.Section A: weakness and/or respiratory failure in ICU and on the ward.43. Causes of paralysis and respiratory failure in the ICU.44. The clinical evaluation of neuromuscular disorders.45. Laboratory evaluation of neuromuscular disorders.Section B: Segmental weakness and/or sensory loss.46. Evaluation of segmental peripheral neurological disorders.Section C: Respiratory failure/diffuse weakness.47. Amyotrophic lateral sclerosis/motor neuropathy.48. Critical Illness neuromyopathy.49. Brachial plexopathy.50. Femoral neuropathy.51. Sensory neuropathy/ganglionopathy.52. Lumbar radiculopathy.53. Guillain-Barre´ Syndrome—demyelinating polyneuropathy.54. Myasthenia gravis—neuromuscular junction.55. Myositis—irritable myopathy.56. Statin-induced myopathy—toxic myopathy/myalgia.Part 5: The Casebook of Clinical/Neurophysiology Consults.57. Occipital blindness and seizures—why?58. Unresponsiveness—coma, vegetative state, or locked-in state?59. Unresponsiveness—organic or psychogenic?60. Patient with a frontal brain tumor—psychiatric depression, paranoia, tumor growth, or status epilepticus?61. Patient with idiopathic generalized epilepsy on valproate—Metabolic encephalopathy or status epilepticus?62. Unresponsiveness—psychogenic, encephalopathy, or limbic encephalitis?63. Respiratory weakness—toxic or metabolic?64. Failure to wean from a ventilator/internal ophthalmoplegia—bulbar dysfunction, neuromuscular junction problem, or polyneuropathy?65. Progressive sensory loss and painful gait—radiculopathy, toxic or infectious neuropathy, or myopathy?66. Slowly progressive leg and arm weakness—radiculopathy, plexopathy, ALS, or CIDP/AMN?67. Progressive thigh pain and leg weakness—radiculopathy, vasculitis, neuropathy, or amyotrophy?Index.