The EditorDr. Goldstein is Professor of Medicine (Neurology) at Duke University and the Durham VA Medical Center, Director of the Duke Center for Cerebrovascular Disease and the Duke Stroke Center, and a Senior Fellow in Duke's Center for Clinical Health Policy Research.He has published over 400 journal articles, reviews, editorials, book chapters, abstracts, and other professional papers including two books. He has served on numerous AHA/ASA committees and guideline writing groups including as Chair of the American Stroke Association Advisory Committee and the AHA Stroke Council Leadership Committee.

• Contributors viiPreface xiClassification of Recommendations and Level of Evidence Table xiiiPart I Overview Topics 11 Stroke Epidemiology 3George Howard and Virginia J. Howard2 Stroke Systems 11Soojin Park and Lee H. Schwamm3 Primordial and Primary Prevention of Stroke 23Nikolaos I.H. Papamitsakis and Robert J. Adams4 Treatment of Patients with Acute Ischemic Stroke 35Harold P. Adams, Jr.5 Intracerebral Hemorrhage 53Opeolu Adeoye and Joseph P. Broderick6 Subarachnoid Hemorrhage 65Jonathan L. Brisman and Marc R. Mayberg7 Prevention of Recurrent Ischemic Stroke 85Jose G. Romano and Ralph L. Sacco8 Post-Stroke Rehabilitation and Recovery 100Pamela Woods Duncan, Danielle Blankenship, and Nicol Korner-BitenskyPart II Special Topics 1139 Stroke in Women 115Cheryl D. Bushnell10 Stroke in Black Patients 129Fernando D. Testai and Philip B. Gorelick11 Stroke in Children 142Gabrielle A. deVeber12 Coagulopathy and Stroke 152Mark Chan, Richard C. Becker, Svati H. Shah, and Steven R. Levine13 Genetics of Stroke 170Natalia Rost and Jonathan Rosand14 Surgical and Interventional Treatment for Carotid Disease 186Kumar Rajamani and Seemant Chaturverdi15 Intracranial Atherosclerosis 195Farhan Siddiq, Burhan Z. Chaudhry, and Adnan I. Qureshi16 Patent Foramen Ovale 206Marco R. Di Tullio and Shunichi Homma17 Vascular Cognitive Impairment 219José G. Merino and Vladimir Hachinski18 Stroke Outcome Assessments 233Linda WilliamsOther Statements Published in 2008 245Index 247COI Table 261A companion website: www.wiley.com/go/strokeguidelines, will keep you informed of new and updated guidelines.

The EditorDr. Goldstein is Professor of Medicine (Neurology) at Duke University and the Durham VA Medical Center, Director of the Duke Center for Cerebrovascular Disease and the Duke Stroke Center, and a Senior Fellow in Duke's Center for Clinical Health Policy Research.He has published over 400 journal articles, reviews, editorials, book chapters, abstracts, and other professional papers including two books. He has served on numerous AHA/ASA committees and guideline writing groups including as Chair of the American Stroke Association Advisory Committee and the AHA Stroke Council Leadership Committee.

• Contributors viiPreface xiClassification of Recommendations and Level of Evidence Table xiiiPart I Overview Topics 11 Stroke Epidemiology 3George Howard and Virginia J. Howard2 Stroke Systems 11Soojin Park and Lee H. Schwamm3 Primordial and Primary Prevention of Stroke 23Nikolaos I.H. Papamitsakis and Robert J. Adams4 Treatment of Patients with Acute Ischemic Stroke 35Harold P. Adams, Jr.5 Intracerebral Hemorrhage 53Opeolu Adeoye and Joseph P. Broderick6 Subarachnoid Hemorrhage 65Jonathan L. Brisman and Marc R. Mayberg7 Prevention of Recurrent Ischemic Stroke 85Jose G. Romano and Ralph L. Sacco8 Post-Stroke Rehabilitation and Recovery 100Pamela Woods Duncan, Danielle Blankenship, and Nicol Korner-BitenskyPart II Special Topics 1139 Stroke in Women 115Cheryl D. Bushnell10 Stroke in Black Patients 129Fernando D. Testai and Philip B. Gorelick11 Stroke in Children 142Gabrielle A. deVeber12 Coagulopathy and Stroke 152Mark Chan, Richard C. Becker, Svati H. Shah, and Steven R. Levine13 Genetics of Stroke 170Natalia Rost and Jonathan Rosand14 Surgical and Interventional Treatment for Carotid Disease 186Kumar Rajamani and Seemant Chaturverdi15 Intracranial Atherosclerosis 195Farhan Siddiq, Burhan Z. Chaudhry, and Adnan I. Qureshi16 Patent Foramen Ovale 206Marco R. Di Tullio and Shunichi Homma17 Vascular Cognitive Impairment 219José G. Merino and Vladimir Hachinski18 Stroke Outcome Assessments 233Linda WilliamsOther Statements Published in 2008 245Index 247COI Table 261A companion website: www.wiley.com/go/strokeguidelines, will keep you informed of new and updated guidelines.

The EditorDr. Goldstein is Professor of Medicine (Neurology) at Duke University and the Durham VA Medical Center, Director of the Duke Center for Cerebrovascular Disease and the Duke Stroke Center, and a Senior Fellow in Duke's Center for Clinical Health Policy Research.He has published over 400 journal articles, reviews, editorials, book chapters, abstracts, and other professional papers including two books. He has served on numerous AHA/ASA committees and guideline writing groups including as Chair of the American Stroke Association Advisory Committee and the AHA Stroke Council Leadership Committee.

• Contributors viiPreface xiClassification of Recommendations and Level of Evidence Table xiiiPart I Overview Topics 11 Stroke Epidemiology 3George Howard and Virginia J. Howard2 Stroke Systems 11Soojin Park and Lee H. Schwamm3 Primordial and Primary Prevention of Stroke 23Nikolaos I.H. Papamitsakis and Robert J. Adams4 Treatment of Patients with Acute Ischemic Stroke 35Harold P. Adams, Jr.5 Intracerebral Hemorrhage 53Opeolu Adeoye and Joseph P. Broderick6 Subarachnoid Hemorrhage 65Jonathan L. Brisman and Marc R. Mayberg7 Prevention of Recurrent Ischemic Stroke 85Jose G. Romano and Ralph L. Sacco8 Post-Stroke Rehabilitation and Recovery 100Pamela Woods Duncan, Danielle Blankenship, and Nicol Korner-BitenskyPart II Special Topics 1139 Stroke in Women 115Cheryl D. Bushnell10 Stroke in Black Patients 129Fernando D. Testai and Philip B. Gorelick11 Stroke in Children 142Gabrielle A. deVeber12 Coagulopathy and Stroke 152Mark Chan, Richard C. Becker, Svati H. Shah, and Steven R. Levine13 Genetics of Stroke 170Natalia Rost and Jonathan Rosand14 Surgical and Interventional Treatment for Carotid Disease 186Kumar Rajamani and Seemant Chaturverdi15 Intracranial Atherosclerosis 195Farhan Siddiq, Burhan Z. Chaudhry, and Adnan I. Qureshi16 Patent Foramen Ovale 206Marco R. Di Tullio and Shunichi Homma17 Vascular Cognitive Impairment 219José G. Merino and Vladimir Hachinski18 Stroke Outcome Assessments 233Linda WilliamsOther Statements Published in 2008 245Index 247COI Table 261A companion website: www.wiley.com/go/strokeguidelines, will keep you informed of new and updated guidelines.