Tom Elliott is Consultant Medical Microbiologist at The Queen Elizabeth Hospital, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK Anna Casey is Clinical Research Scientist in the Department of Clinical Microbiology at The Queen Elizabeth Hospital, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UKPeter Lambert is Professor of Microbiology in the School of Life and Health Sciences at Aston University, Birmingham, UKJonathan Sandoe is Consultant Microbiologist and Honorary Senior Lecturer in the Department of Microbiology at Leeds Teaching Hospitals NHS Trust and University of Leeds, Leeds, UK

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• Preface vContributors viiBasic microbiology1 Basic bacteriology 3Peter Lambert2 Classification of bacteria 12Peter Lambert3 Staphylococci 16Tom Elliott and Peter Lambert4 Streptococci and enterococcci 20Anna Casey5 Clostridia 26Tony Worthington6 Other Gram-positive bacteria 30Anna Casey7 Gram-negative cocci 36Jonathan Sandoe8 Enterobacteriaceae 40Peter Lambert9 Haemophilus and other fastidious Gram-negative bacteria 45Jonathan Sandoe10 Pseudomonas, Legionella and other environmental Gram-negative bacilli 51Peter Lambert11 Campylobacter, Helicobacter and Vibrio 54Martin Skirrow, Cliodna McNulty and Tom Elliott12 Treponema, Borrelia and Leptospira 58Susan O’Connell13 Gram-negative anaerobic bacteria 62Peter Lambert14 Chlamydiaceae, Rickettsia, Coxiella, Mycoplasmataceae and Anaplasmataceae 64Jonathan Sandoe15 Basic virology 69Peter Mackie16 Major virus groups 75Peter Mackie17 Basic mycology and classification of fungi 93Elizabeth Johnson18 Parasitology: protozoa 101Peter Chiodini19 Parasitology: helminths 112Peter ChiodiniAntimicrobial agents20 Antibacterial agents 127Peter Lambert21 Antifungalagents 144ElizabethJohnson22 Antiviral agents 147Eleni NastouliInfection23 Diagnostic laboratory methods 157Tony Worthington24 Epidemiology and prevention of infection 167Barry Cookson25 Upper respiratory tract infections 177Jonathan Sandoe26 Lower respiratory tract infections 183Shruti Khurana27 Tuberculosis and mycobacteria 189Sumeet Singhania28 Gastrointestinal infections 193Tariq Iqbal29 Liver and biliary tract infections 202David Mutimer30 Urinary tract infections 207Chris Catchpole31 Genital infections 210Kaveh Manavi32 Infections of the central nervous system 220Erwin Brown33 Bacteraemia and bloodstream infections 229Tom Elliott34 Device-related infections 233Tom Elliott35 Cardiovascular infections 238Richard Watkin36 Bone and joint infections 241Jonathan Sandoe37 Skin and soft-tissue infections 246Supriya Narasimhan and Rabih Darouiche38 Infections in the compromised host 257Tom Elliott39 Infections caused by antimicrobial-resistant bacteria 260David Livermore40 Perinatal and congenital infections 264James Gray41 Human immunodeficiency virus 271Kaveh Manavi42 Miscellaneous viral infections 277John CheesbroughSelf-assessmentSelf-assessment questions 285Answers to self-assessment questions 300General subject index 309Organism index 317