"Incredible detail to immunologic mechanisms is the strong point of the book. The bibliography at the end of each chapter is exhaustive, sometimes citing over 300 references.The pharmacokinetics of cytokines are meticulously discussed and diagrammed. Tables summarizing the results of clinical trials to date are peppered throughout the book. The authors are careful not to draw conclusions that do not have support from prospective randomized clinical trials. It is an excellent source to become familiar with current research and experimental protocols for advanced melanoma. Researchers and directors of melanoma clinics at tertiary care facilities will want to have this book as a resource."-Weighted Numerical Score: 100 - 5 Stars!-Doody's Health S ciences Book Review Journal

• I Perspective on the Clinical Disease.- 1 Management of Primary Malignant Melanoma.- 2 A Pathologist’s Perspective on Prognostic Featuresof Malignant Melanoma.- 3 Clinical Prognostic Factors and Staging.- II Biological and Targeted Therapeutics.- 4 Principles of Antitumor Immunity and Tumor-Mediated Immunosuppression.- 5 Immunotherapy of Advanced Melanoma Directed at Specific Antigens.- 6 Melanoma Antigens: Vaccines and Monoclonal Antibodies.- 7 Interleukin-2.- 8 Interleukin-12: Immunologic and Antitumor Effects in Human Malignant Melanoma.- 9 Interferons: Preclinical and Clinical Studies in Melanoma.- 10 Biochemotherapy of Melanoma.- 11 Signal Transduction Abnormalities as Therapeutic Targets.- 12 Tumor Angiogenesis.- 13 Antiangiogenic Therapy for Melanoma.

"Incredible detail to immunologic mechanisms is the strong point of the book. The bibliography at the end of each chapter is exhaustive, sometimes citing over 300 references.The pharmacokinetics of cytokines are meticulously discussed and diagrammed. Tables summarizing the results of clinical trials to date are peppered throughout the book. The authors are careful not to draw conclusions that do not have support from prospective randomized clinical trials. It is an excellent source to become familiar with current research and experimental protocols for advanced melanoma. Researchers and directors of melanoma clinics at tertiary care facilities will want to have this book as a resource."-Weighted Numerical Score: 100 - 5 Stars!-Doody's Health S ciences Book Review Journal

• I Perspective on the Clinical Disease.- 1 Management of Primary Malignant Melanoma.- 2 A Pathologist’s Perspective on Prognostic Featuresof Malignant Melanoma.- 3 Clinical Prognostic Factors and Staging.- II Biological and Targeted Therapeutics.- 4 Principles of Antitumor Immunity and Tumor-Mediated Immunosuppression.- 5 Immunotherapy of Advanced Melanoma Directed at Specific Antigens.- 6 Melanoma Antigens: Vaccines and Monoclonal Antibodies.- 7 Interleukin-2.- 8 Interleukin-12: Immunologic and Antitumor Effects in Human Malignant Melanoma.- 9 Interferons: Preclinical and Clinical Studies in Melanoma.- 10 Biochemotherapy of Melanoma.- 11 Signal Transduction Abnormalities as Therapeutic Targets.- 12 Tumor Angiogenesis.- 13 Antiangiogenic Therapy for Melanoma.

"Incredible detail to immunologic mechanisms is the strong point of the book. The bibliography at the end of each chapter is exhaustive, sometimes citing over 300 references.The pharmacokinetics of cytokines are meticulously discussed and diagrammed. Tables summarizing the results of clinical trials to date are peppered throughout the book. The authors are careful not to draw conclusions that do not have support from prospective randomized clinical trials. It is an excellent source to become familiar with current research and experimental protocols for advanced melanoma. Researchers and directors of melanoma clinics at tertiary care facilities will want to have this book as a resource."-Weighted Numerical Score: 100 - 5 Stars!-Doody's Health S ciences Book Review Journal

• I Perspective on the Clinical Disease.- 1 Management of Primary Malignant Melanoma.- 2 A Pathologist’s Perspective on Prognostic Featuresof Malignant Melanoma.- 3 Clinical Prognostic Factors and Staging.- II Biological and Targeted Therapeutics.- 4 Principles of Antitumor Immunity and Tumor-Mediated Immunosuppression.- 5 Immunotherapy of Advanced Melanoma Directed at Specific Antigens.- 6 Melanoma Antigens: Vaccines and Monoclonal Antibodies.- 7 Interleukin-2.- 8 Interleukin-12: Immunologic and Antitumor Effects in Human Malignant Melanoma.- 9 Interferons: Preclinical and Clinical Studies in Melanoma.- 10 Biochemotherapy of Melanoma.- 11 Signal Transduction Abnormalities as Therapeutic Targets.- 12 Tumor Angiogenesis.- 13 Antiangiogenic Therapy for Melanoma.