Pathogen Genomics

Impact on Human Health

AvKaren Joy Shaw

Häftad, Engelska, 2012

Del i serien Infectious Disease

1 107 kr

Beställningsvara. Skickas inom 10-15 vardagar. Fri frakt över 249 kr.

Beskrivning

The authors' cross-disciplinary approach, with expertise acquired from studying disease-causing viruses, bacteria, fungi, and protozoa, reveals how sequence information from diverse pathogens has uncovered novel targets for drug discovery, antigenic determinants for vaccine development, as well as diagnostic tools.

Produktinformation

Utgivningsdatum:2012-12-12
Mått:178 x 254 x 19 mm
Vikt:634 g
Format:Häftad
Språk:Engelska
Serie:Infectious Disease
Antal sidor:309
Förlag:Humana Press Inc.
ISBN:9781468496833

Utforska kategorier

Recensioner i media

"As a result of this comprehensive genomic information relying on new technologies and experimental tools, a novel quality in understanding pathogenicity has been reached. This is illustrated in the book in an impressive manner." -Proteomics

Innehållsförteckning

I Viruses.- 1 Antiviral Drug Target Discovery with DNA Microarrays.- 2 Chipping Away at HIV Pathogenesis.- 3 Microarray Analysis of Human Papillomavirus Pathogenesis.- 4 Ribozymes as Gene Therapeutic Agents for HIV/AIDS: A Potential Paradigm Shift.- II Bacteria.- 5 Genomics and New Technologies Applied to Antibacterial Drug Discovery.- 6 Genomics of the Mycobacterium tuberculosis Complex and BCG Vaccines.- 7 Bacterial “Genes-to-Screens” in the Post-Genomic Era.- 8 DNA Microarray Expression Analysis in Antibacterial Drug Discovery.- 9 The Influence of Genomics on the Molecular Epidemiology of Nosocomial Pathogens.- 10 Borrelia Genomics as a Tool for Studying Pathogenesis and Vaccine Development.- III Fungi.- 11 Antifungal Target Discovery and Evaluation: Lessons from Saccharomyces cerevisiae.- 12 Antifungal Drug Discovery: Old Drugs, New Tools.- 13 Cryptococcus neoformans: A Molecular Model for the Study of Fungal Pathogenesis and Drug Discovery in the Genomic Era.- 14 Antifungal Target Selection in Aspergillus nidulans: Using Bioinformatics to Make the Difference.- 15 Functional Genomics of Histoplasma capsulatum: Dimorphism and Virulence.- 16 Gene Finding in Coccidioides immitis: Searching for Immunogenic Proteins.- IV Protozoa.- 17 Toxoplasma gondii: A Model for Evolutionary Genomics and Chemotherapy.- 18 The Molecular Biology and Pathogenicity of Entamoeba histolytica.